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>Help, advice, guidance on medications and dosages
>HRT related medical experiences and research
>Availability and pricing of medications
>Rational and scientific discussion

Please take the survey and help us determine the best medications, dosages, and treatment regime to get the results we want.

Because the situation is constantly changing and different in every country, please read the thread and ask questions for advice on obtaining HRT meds and appropriate medical help.

▶ Survey: https://1drv.ms/xs/s!AudRJceTA5C9c2G5lCV2Avq0kQ0
▶ Raw survey data: https://1drv.ms/x/s!AudRJceTA5C9cyIWo6_X14AvHyM
▶ HRTGen Data Analysis: https://1drv.ms/f/s!AudRJceTA5C9gRLLWnbpdzlIxe4r
▶ HRT Anime Girl Info Sheets: https://1drv.ms/f/s!AudRJceTA5C9gQnyM7wxZcBGWRzW
▶ Pill Identification: https://www.drugs.com/imprints.php
▶ DrugBank Database: https://www.drugbank.ca/
▶ Basic HRT info: https://apps.carleton.edu/campus/gsc/assets/hormones_MTF.pdf
▶ Hormone target ranges: http://www.hemingways.org/GIDinfo/hrt_ref.htm
▶ Endocrine Society guidelines: https://academic.oup.com/jcem/article/102/11/3869/4157558
▶ TransDIY: https://www.reddit.com/r/transDIY
▶ Breast development info: https://genderanalysis.net/resources/studies-on-trans-womens-breast-development/
▶ Blood testing (US Only): https://www.privatemdlabs.com/
▶ Blood testing (UK Only): https://www.medichecks.com/
▶ Blood testing (Canada Only): https://bloodtestscanada.com/
▶ Lab test guide (with reference ranges): https://www.healthcare.uiowa.edu/path_handbook/index.html
▶ FtM HRT guide: http://www.ftmguide.org/ttypes.html
▶ /HRTGen/ Archives: https://1drv.ms/w/s!AudRJceTA5C9fiPMDzSLX7xF9MI
▶ More Archives: List at 8ch /tttt/ HRT Info Dump sticky
Previous thread: >>10197097
>>
shesalady.co.uk has had a lot of success reports, but email can work better for ordering from them.
eu-aibolit.com has been getting more success reports lately too.
unitedpharmacies-uk.md seems to work for the UK.
inhousepharmacy.vu and alldaychemist.com are others.
eu-aibolit.com has been getting more success reports lately too.
>>
Asked this question a few threads ago but didn't get an answer: how can mones cause constipation, and what can I do against it? I began HRT on 25mg cypro, 2mg sublingual E three weeks ago and became constipated a few days after starting. I've never had any serious constipation before, and I didn't change my diet around the time I started, with the only exception being that I stopped drinking alcohol a month beforehand. I feel no urge to defecate at all anymore; my poop is extremely dry and hard and I have to force it out with great effort. I've since adjusted my diet to include lots of fiber, am drinking huge amounts of water daily, and am even taking laxative pills every couple days but none of it helps. Anyone got any idea at all?
>>
>>10239423
I used to answer lots of questions but I've been too busy lately and haven't been able to keep up. I feel bad you haven't gotten a response.
I don't have a definitive answer at the moment, but hrt can definitely change your digestive patterns. I think the details of that vary though as to whether it causes constipation or the opposite.
Your body does need some time to adjust, so it might get better over time. If laxatives aren't working I'd suggest you stop taking them, since that's yet another thing your body needs to adjust to.
You might want to try eating greasy foods and see if that softens things up a bit.
If you're really desperate you could try drinking mineral oil. Use a small amount, no more than 45 mL, but you might want to try 15 mL the first time to be safe and see how you tolerate it. You shouldn't consume it within two hours of meds or food. Don't use it more than a few days.
Any kind of laxative isn't good long-term though. So you have to hope that your body adjusts and that a change of diet can help. If it's really bothering you and nothing helps consulting with a doctor is a good idea.
>>
>>10239457
Thanks a bunch, that was really helpful!
>>
>>10239541
You're welcome!
>>
Just got my Cypro + Estrofem combo from Shesalady. The Estrofem checks out, 2mg is what I expected, but the Cypro is a combination of 2mg Cypro and 0.035mg Ethinylestradiol. These look like birth control pills to me. 2mg Cypro seems incredibly low, especially for me coming off Bica so my T production is probably quite high.

I don't think this is a case where they expect me to take multiple pills per day, because I ordered a 6 month supply and taking one Cypro a day gives me about 5.5 months.

What's up with that? Anyone got different results from Shesalady? Or know if 2mg is actually somehow the best dosage and I'm crazy?
>>
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>>10239631
why did you order the bundle? they are selling estrofem and cpa (50mg) separately as well.

there are some people who are on just E, so possibly there is a regimen with just a small amount of AA. the ethinylestradion is said to be unsafe however.
>>
Posted my question last thread but it never got answered :(
I'm in the U.S., gonna start non-DIY soon. What should I try to ask for?
inb4 >just diy
DIY isn't an option for me
>>
>>10239631
Their bundle thing contains crappy ethinylestradiol which is really bad stuff; you probably made the mistake to order that. I bought their cypro and it's normal 50mg pills.
>>
my e level is over 1000 pg/ml. I'm only on 5mg weekly, blood test right before next injection. why tf is my e still so high? taking estradiol valerate, not cypionate.
>>
does anyone know where i can purchase estradiol and spiro in sydney, australia without a prescription?
>>
MTF here, could bad levels and a lot of anxiety/stress be severely slowing down my hair growth?
>>
>>10239658
>>10239740
I saw that they had normal Cypro as well so I assumed it'd just be easier to get the bundle (also it's cheaper).
I guess I'll contact them again to get either 50 or 25mg pills, and take these in the meantime. I've read that ethinylestradiol has blood clot problems so I want something less likely to kill me anyway.
>>
is it viable to DIY without acess to blood tests
>>
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Switching from 3mg progynova pills over to 100mcg patches soon. Is it an improvement?
>>
>>10240054
Yes but you should try going legit to get monitored and everything.
I likely won't be able to get blood tests until I'm about 9+ mo in but I am still trying to get a legit prescription and stuff.

If you have private testing where you live do that though. But not everywhere has ptivate testing
>>
Anyone know what could happen if i take both Cipro and Spiro?
>>
>>10240516
You explode
>>
>>10240617
It's a serious question, i need Spironolactone, because of hyperaldosteronism.
But T levels although low... they could be lower.
Endo says its fine, we are lowering Spiro and adding Cipro to the mix, but i really want to hear you guys opinion.
>>
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Aight so I know I've asked this before but does anyone know how to accurately dose estrogel?

Sublingual sucks and makes me feel shitty and tired by the end of the day so I wanna switch

https://www.inhousepharmacy.vu/p-297-oestrogel.aspx

I'm trying to find more insight about how much of this you use for one dose and/or what the closest equivalent of a 2mg sublingual pill would be so that I can measure out how much I need to buy. Any ideas?
>>
>>10240257
Maybe. There's no way for us to know for certain unless you post the results of a blood test. However, most people achieve higher estradiol levels on patches than they do on tablets. Additionally, patches will give you more stable estradiol levels and reduce impact on your liver.
>>10240516
>>10240637
I don't see any issues with taking both. Just to be safe, you may want to measure your cortisol levels before and after adding cypro. Both cypro and spiro affect cortisol production, so there's some potential for interaction there (cypro decreases it via GR agonism, spiro increases it via MR antagonism).
>we are lowering Spiro
That's good, because I was about to suggest that. :) The spiro dose required to treat hyperaldosteronism is lower than the dose required to block androgens.
>>
>>10240257
100mcg patch = about 2mg, but you get better E1/E2 on patches so watch your levels carefully to see if you need to multiple patches at once or not
>>
>>10239388
Is it viable to take both oral e and use patches at the same time? Will this cause some sort of competition for receptors or anything of that nature?

I remember reading phytoestrogens (although weak) compete and steal space, for lack of better words, that would be filled up by patch use or oral estrogen if you were to take both, is that true?
>>
>>10241777
I am doing 2 patches and 2mg sublingual and seeing pretty good early (4mos-ish) results

But admittedly it is my second time after getting hondosed for years and taking a literally five year break/"detransition". My tits are bigger than they ever were first go round with my current regimen, but i had tits when i started this time so unsure of root cause of success
>>
>>10241875
Why the 2mg Sublingual? How much growth have you experienced?
Just going from 2mg Sub to 1 patch (Estradot) got me from A to B in 3 months

Nearly identical situation, cept it was a 3 year break.
>>
>>10239631
Sounds like Diane 35 which has been linked with an increased risk of DVT. It's not for general birth control use, only for women who also have some androgen-dependent condition like hirsutism.
>>10239721
Injections are best for estradiol. Patches second best if you can tolerate them. Availability of gels and insurance coverage for them is poor in the US though they would be good. If you get pills get the Teva generics - ask for them if needed - because they dissolve really well.
If you can't get a GnRH agonist like Lupron/leuprolide or goserelin due to cost, then get bicalutamide. You should probably start at 50 mg unless you have naturally low T. If estradiol manages to lower your T you could consider going to 25 mg, which is the dose for women who need androgen blockers.
>>10239743
Maybe your liver isn't clearing it out of your system very well. Are you sure you're injecting the correct amount? Estradiol valerate is sold in several different concentrations and it would be easy to get mixed up.
>>10239878
Maybe. Stress is always bad, and to the extent estradiol stimulates hair growth low levels would hurt.
>>10240054
It's not a good idea to go totally blind. You want to adjust your dose to actual levels, and you want to be sure nothing bad is happening. Getting a baseline test and a couple tests in the first six months is a very good idea. If everything is stable and nominal and you don't have health symptoms, then you could back off on tests. Antiandrogens are the biggest concern really.
>>
>>10240660
There's an approximate equivalence in the OP infographic. You'll still need to test to make sure you're getting decent levels.
>>10241777
You can take oral and patches because the estradiol is the same, bioidentical, in both cases.
Phytoestrogens would be problematic though. Best to avoid them.
I'm assuming you want to save money or the annoyance of wearing two patches at the same time?
>>
>>10241902
This is all anecdotal and shitty science of course but honestly just bc I wanted to see what it would do, I was on 4mg sublingual back in the day (+spiro, now doing cypro, which i also think is helping a lot). Back in teh day i would talk to euro trannies online who were on CRAZY doses by this thread's standards, l remember like 10/12mg daily or maybe the injectable equivalent thereto, and I always resented the endo and later informed consent place for never letting me go past 4 and wasting my time w progy, etc, and partially that was kinda my thought I guess even though I know that's retarded.

However I do think adding the oral on top of the patches is kinda what made me start to feel like i felt at the very beginning last time, my tits started hurting again, etc. Im visibly storing body fat in a different way than I ever did during hondose days, although even hondose (and stopping hondose) did change my face a lot. Possibly I went too quickly as I was eager to get back in and felt like an idiot for not doing blackmarket years ago. YMMV re dosage obviously, I am literally huge - 6'4 200
>>
>>10241945
But do those euro trans have better results? I mean is there that much benefit to going to higher levels than cis women normally have?
>>
>>10241955
It certainly seemed to me at the time they were having better results.

This is dangerous thought I know but to my mind, I don't totally understand the "emulation of cis female levels" thing - nothing else about you is like a cis female, why would cis female levels be adequate to fight the dreadful uphill battle of this lifestyle? Maybe someone better informed than me can speak to that
>>
>>10241963
That's not true that nothing is like a cis female. We're all human. I don't see any fundamental difference in a quick search in estrogen receptor expression between sexes. There could be some brain differences, but then it looks like mtf brains are shifted female. Cancer cells seem to have some sex-based differences. The hormonal environment can affect all this though and I didn't do a detailed search.
The biggest issue is not male/female, it's the age at which you start. Ideally you'd start when female puberty is supposed to start, and not mess around with male puberty at all.
But hormones will still change things. XY individuals have all the possible genes. You can think of it like a book, and some parts are "male" and some "female". Sex hormones dictate which parts of the book are read. XX individuals lack genes related to spermatogenesis mainly. SRY could be responsible for some subtle differences, and there are epigenetic factors too, but for the most part sex hormone balances will dictate which parts of the DNA book are read out and acted upon. Hormones are not just cosmetic.
>>
>>10240794
Yeah, Endo made me take a cortisol test, twice in the same day actually. It came out fine.

Thank you Anon
>>
I started HRT while studying abroad using cypro. I'm moving back to America soon and when I leave I'll have been on HRT about three months. What should I do as far as replacing cypro?
>>
>>10242134
The FDA permits you to import drugs not approved in the US as long as it was prescribed by a doctor outside the US:
https://www.fda.gov/aboutfda/transparency/basics/ucm194904.htm
As far as I can tell, you qualify for all the requirements.

Most trans women in the US are prescribed spironolactone, but it's isn't a very effective antiandrogen. See >>10227468. The closest equivalent to cypro in the US would be GnRH agonist injections. Goserelin, leuprolide, and histrelin are the most common. Another option would be bicalutamide, but it's not frequently prescribed to trans people.
>>
>>10242167
I'm diy and leave in about a month. I doubt I could get a proper prescription by then :(
>>
>>10242034
This feels like a deliberate and kinda reddity misreading based on me being dramatic, lol. This is not the thread for it really but: Fuck off with the brain stuff, you are free to believe what you want but personally and scientifically there is no physical difference between me and a "normal" male besides those created from years of hormones. I'm a specific kind of retard, and I'm interested in cosmetic changes.

I am just saying I think the hormone levels necessary to make a grown man look more like a woman and the hormone levels necessary to make a non-differentiated youth look like a woman or a woman look like a woman *may not necessarily* be the same, however romantic your understanding of the endocrine system is. And I admit I could be wrong. I get basically what you're saying, but I want all the help I can get, for aforementioned uphill battle reasons. If there's even a chance that having that second patch on is helping me more than it's hurting me, I'm going to keep it on, lol

This would make more sense to me if it was in the realm of like bodybuilding protein arguments? My body is just flushing the excess? Anecdotally, I've seen results (w "excess" e, not excess protein). My levels haven't been tested in a few months, I'll circle back when I have data lol. Possibly I just dont absorb E as good as the rest of you or whatever the fuck.

>>10242134
... buy black market cypro online
>>
>>10242189
Is cypro that easy to get black market in the US? Good to know
>>
>>10242206
Its not heroin lol
>>
>>10242211
Is there price gouging? I started HRT in the UK and it would be shame if the price is like double back home
>>
>>10242232
I don't really know (as drug is not available in us) but I don't really think so. Do you not remember interacting with the *legit* US healthcare system? "Price gouging" is a kind way to describe it
>>
>>10242253
Haha yeah. I might try to stock up and travel with it anyway, but it's good to know it's still available on black market. Thanks :)
>>
Can someone just tell me not to kill myself. I need direction.
>>
>>10242284
Don't kill yourself
>>
Does anyone know doctors in southwestern ontario that will do informed consent or prescribe without having to go to therapy?
>>
>>10242317
k
>>
>>10239388
hi can i please get some advice on taking low dosages of hrt? what do i need and how much? thanks
>>
>>10241931
Saving money, patches seem very expensive to keep up, my aa is cypro, though.
>>
does anyone know if theres a way to specifically lose lean muscle mass? would the fat distribution changes get rid of it and redistribute it as female fat, or would i just have to starve myself until its all gone?
>>
>>10242428
rainbowhealthontario. Look for clinics outside to Toronto. Good luck.
>>
My doctor is prescribing me 12.5 mg of cypro and no e. Is this legit or are they fucking with me?
>>
>>10243108
>12.5mg cypro
sometimes legit, usually it's 25mg but either way it always depends on how well it werks on your machine
>no e
are they trying to give you osteoporosis? wtf
>>
So I'm pretty much banned from inhousepharmacy because they screwed up and sent my pills without receiving my payment. If I'm forced to switch from cypro (i live in US so can't get script), what would be the best alternative?
>>
>>10243108
I mean for like a month this is fine. 12.5mg cypro is ABSOLUTELY enough to start nuking t.

Doctors will do this to gauge your seriousness. It's fucked. How old are you
>>
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>>10243108
Mine has had me on 2mg E for 10 weeks and is now on holiday for 2 weeks. I want to kick him in the dick.
>>
>>10243159
Im 21. I have a psych referral and everything so I don't know how much more serious I could get. I spent thousands of dollars and months just seeing a shrink so I could bypass the wait time in IC clinics.
>>
>>10242428
I don't know specifically, but around Windsor you could look at:
http://wetranssupport.ca/
http://www.windsorfht.ca/lgbt/
You can see if you can find anything at https://www.rainbowhealthontario.ca/
I don't see anything good around London.
>>
>>10243156
Bica.
>>10243235
The psych stuff is BS. ICD-11 is moving trans stuff out of the mental health chapter. I also read something that they wanted the criteria to be usable for diagnosis by ordinary doctors.
Family doctors/GPs are perfectly capable of doing hrt too. Endos are a racket for hrt. They should only be needed if there's an unusual problem that comes up.
>>
>>10243806
I live in Canada and it's slightly different. Due to some recent legislation changes a lot trans people are coming out of the woodwork for HRT, but this causes huge wait times for informed consent clinics. Most other GPs need a referral from a psych, and endos don't see you unless you got a referral from a GP. So anywhere you go you got a lot of hoops to jump through to even start HRT.
>>
>>10243780
that sucks because I live in London.

I know Dr James Martin at Southern Ontario Fertility Technology used to prescribe without hassle but google says theyre closed permanently. anyone know if he is still practicing somewhere else?
>>
>>10243981
I understand about the hoops. It's the reality but it's an unnecessary reality imho.
>>10244049
I ran across a mention of him. Someone said his medical license was suspended. I don't know why.
>>
>>10244049
>>10244251
I heard he was prescribing really wierd doses and drugs to trannies and someone reported him. It was some kind of nasal AA and wierd estrogen doses.
>>
>>10242284
I decided that you can always try to make things better for yourself, and that you'll never know how things would've turned out if you kill yourself. Think about it. Wouldn't it be better to use it as an absolute last resort? I can't say I know your situation, but things have a chance to get better, and thought it may seem hard, you should really take it.
>>
>>10244338
>nasal AA
Probably buserelin. There's nothing wrong with buserelin.
>wierd estrogen doses
What were the doses?
>>
>>10243981
I just went to a psychologist and told them I was self-medding. She referred me to a trans-friendly GP who did my blood tests and now I have a referral to the gender clinic.

No clue how you do it without self-medding though lol
Plus I have I think 5ish years worth of cypro and E so I haven't minded the wait. By the time I see an endo and get a prescription I'll be close to a year on hrt though.
>>
>>10244898
>Plus I have I think 5ish years worth of cypro and E
But what about the expiration dates?
>>
>>10244974
I've read articles and the drugs don't expire really, it's just if the fillers and stuff are exposed to moisture.
You can store them in the dark and in the freezer and they'll last way longer. I dunno if I'll need to though.
>>
Anyone else experienced only growing one hip? What doses were you on and did the other one grow eventually??
>>
I think I upped my doses too fast, is there any point in going back?
>>
>>10245336
The only thing I could say is you could try and see if it helps. If staying at a high dose isn't working, then you might as well try something different.
>>
>>10240660
>>10241931
Thanks for the help!

Follow-up question: how much more efficient is estrogel than pills?

IHP recommends a starting dose equivalent to 1.5mg of estradiol, whereas I started on 2mg pills and will be going up to 4. Should I do 6.25g of gel (3.75mg) to get as close to 4 as possible, or should I do 5g (3mg) to just play it safe and double their starting dose?
>>
>>10247201
>how much more efficient is estrogel than pills?
It works better for some people and worse for others. Typically transdermal estradiol will achieve a higher E2/E1 ratio, but whether or not that actually results in improved feminization is debatable (there haven't been any scientific studies).
>Should I do 6.25g of gel (3.75mg) to get as close to 4 as possible
4 mg transdermal estradiol isn't the same as 4 mg oral estradiol. Oral estradiol goes through a different metabolism process than transdermal estradiol, so they have different bioavailability. I think the safest option is to use conservative starting dose then work your way up until your serum estradiol is at the target concentration (100-200 pg/mL).
>>
>>10247365
>It works better for some people and worse for others.
Hmm, gotcha.

>I think the safest option is to use conservative starting dose then work your way up until your serum estradiol is at the target concentration (100-200 pg/mL).
Even if I'm already on a higher sublingual dose?
I guess that makes sense, though.

How long do you recommend I taper up for? I'm only planning to be on it for a little over a month at an absolute maximum, since that's when I get my injection script, so it sounds like if that's really the best way to do it then maybe sticking to pills would be better sadly
>>
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>>10247521
Different anon, but I'd say whatever your levels are I'd want to go straight to roughly equivalent levels, then adjust from there.
One problem with gel is that you might need quite a bit of it. 7.5 g of 0.06% gel or 4.5 g of 0.1% gel is what I'd aim for based on the attached graph. Estrogel is 0.06%. The lower line is estradiol. That would get you around 180 pg/mL if it scales linearly, which is not necessarily the case. Levels can often increase more than linearly, so you might want to cut the dose a bit to start.
>>
>>10248427
>7.5g
Holy shit, that's a lot
I was planning on going with either 5g (3mg) or 6.25g (3.75mg) based on the rough conversion in the OP and on IHP's website. Their info says that 2.5g of the gel contains 1.5mg of estradiol
>>
>>10239388
How do I make my transition from cypro to bica as smooth as possible?
>>
>>10248824
You could try the IHP doses first and see how the levels work out. Like I said it seems common that levels go up faster than linearly.
>>10249092
I think that's easier than going the other way since bica should start blocking effectively within hours. You could drop down to 12.5 mg cypro if you haven't already for 3 or 4 days, and if you feel OK just stop cypro, then take bica the next day. You could start on a half dose of bica the first day then a full dose the second day.
As long as you keep up your estradiol dose and your T levels are currently nuked there shouldn't be much of a change in T during that time.
>>
my climara patch has like white spots on it is that normal?
>>
I’m one month on hrt 25mg crypto and 2mg estrofem ive noticed a lot of changes is this normal for which a short time is my dose right I mean like a lot
>>
>>10249644
>crypto
>>
>>10239393
>shesalady.co.uk has had a lot of success reports, but email can work better for ordering from them
What are their shipping times to the US like?
Their estrofem is sooooooooo much cheaper than it is on IHP but I'm only going to have my PO Box until the end of the month before I move so I'm worried it'll come too late
>>
>>10249680
Sorry cypro
>>
>>10249747
I personally don't know. IHP seems like the main site for those in the US these days. I hope someone else can answer.
>>
>>10249767
Yeah, I only need enough for like another month and then I'll be fine so I'm alright with paying more for IHP just to be safe and know it has a much better chance of getting here on time. In the future I'll probably go to them for cypro and stuff just bc it's so ridiculously cheap tho

Plus I've heard shesalady is understandably pretty backed up at the moment so it might take them a little while to ship
>>
Is there any reason my levels are varying crazily while on patches? Last time I had 285 E on 25 bica and .2mg patches and without changing anything, this time I tested 682 E. wtf is happening?
>>
Does anyone have experience with Lupron? I heard about the testosterone flare that comes with taking it. Is it safe to go from cypro to Lupron?
>>
>>10249869
I don't have experience but any flare isn't going to last long. It's not going to have any significant effect long-term. There's no reason why you can't switch that I know of, and lupron should have less risk of side effects.
>>
Is a lot of breast growth and face changing and hair loss on body normal for one month on hrt or did I fuck up
>>
>>10249909
no it is not normal but it is considerably lucky
>>
>>10249956
Are you sure I just haven’t fucked my dose up I’m on 25 cypro and 2 estro I was going to up the estro on month 3 but I don’t know now
>>
>>10249995
Did you have gyno ahead of time? Naturally low T? You're getting an unusually good outcome.
>>
>>10250015
I had a bit of gyno not a lot my t was normal really want to if I’ve fucked up my dose
>>
>>10249869
>I heard about the testosterone flare that comes with taking it.
A couple weeks of high testosterone won't hurt you in the long run.
>>
>>10250027
No, your dose is a standard starting dose.
>>
>>10250065
Ok that’s good to hear I was going to up it to 4 mg estro after 3 months should I still do that if I keep developing like I am or should I leave it longer
>>
>>10243981
>recent legislation changes
Explain please
>>
>>10250080
Eventually you'd want to up it. If you feel well and things are going well you can wait longer. I'd aim for the 3-6 month time frame for upping. If you seem to stall out on changes or you're not feeling totally well due to low E you can go ahead and up, but I wouldn't wait more than 6 months.
>>
>>10250140
Ok will do thanks for the help
>>
>>10250101
Basically CAMH, who were the main gatekeepers of the entire process got removed from the guidelines and the focus was placed on primary care physicians. Plus it doesn't help that the transcare training sessions were moved up to Thunder Bay.
>>
>>10249995
Congratulations, you've gotten more development on 1 month hrt than I've gotten on 2 years.
>>
>>10250032
Can I still take cypro during that time to suppress the flare?
>>
>>10250243
That may be true but mine look weird I’d rather have ones that looked good I’m sure yours do
>>
>>10250234
Just go to any GP and ask for a referral to a psych. Then they'll refer you to an endo.
If you're in Ontario you can get private blood testing so self-medding is super easy while you wait.
>>
>>10250247
You can do whatever you want, but that doesn't mean it's a good idea. Cypro has two mechanisms for decreasing the effects of androgens:
1. Binding to androgen receptors, but producing no biological response. This prevents androgens such as testosterone and DHT from binding to the receptor and causing masculinization.
2. Binding to progesterone receptors in the hypothalamus and producing a strong biological response. In response to this, the hypothalamus produces less GnRH, which causes the pituitary gland to produce less LH and FSH, which causes the testes to produce less testosterone.
GnRH agonists act in place of GnRH, bypassing the second mechanism of cypro, so you would still get the testosterone flare. This leaves only the first mechanism, which won't be as effective in the presence of high testosterone.

If you truly wanted to prevent the testosterone flare from having any effect, you would have a couple options:
A. Take a high dose of a strong androgen receptor antagonist like bicalutamide for the first 2-3 weeks of taking a GnRH agonist.
B. Take a GnRH antagonist instead of a GnRH agonist. GnRH antagonists do not cause a testosterone flare.
Really, though, you shouldn't do any of this. Just live with having high testosterone for a couple weeks. It truly will not hurt you.
>>
>>10239388
I’m switching off spiro to cypro. Should I do 25 or 50 mg cypro?
>>
>>10250790
Start with 25mg
>>
>>10250234
>training sessions were moved up to Thunder Bay.
jfc that's remote. Somebody was doing or returning a favor for someone.
> focus was placed on primary care physicians
Only problem is that a lot of them don't seem to want to touch trans stuff.
>>10250247
It's not uncommon for AAs to be used with GnRH agonists. It seems especially common to do that with bica, but I've seen cypro and agonists used together. I suppose you could do it but I don't think it's really necessary.
>>10250790
Go with 25. It's enough as long as you don't have super high T levels.
>>
just hypothetically, what would be the best way to sneak someone testosterone without them knowing? would it work if you mixed testosterone gel with their lotion?
>>
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So I got my 6 months blood results, I don't have a baseline because I diy'd for a long time, so this is all I have to go on. Ignore a lot of the ranges, the people doing it didn't read the notes and gave me male reference ranges. My E is a little high on 2x 100mcg/day patches and I have the prolactin levels of a pregnant woman apparently. My GP referred me to a specialist for that so I'm not too concerned about that part.

Anything else I should be concerned about?
>>
>>10251418
Oh yeah, why is my FSH and LH so low? I'm not on a GnRH agonist, I'm on 25mg/day cypro. My T is also a little high because I fucked up my cypro dose the month before.
>>
It's been nearly a month and I've been basically taking 25mg Cypro and 2mg strofem.

Nothing seem to have changed whatsoever. I'm very confused, do I need to wait 2 months for any possible results?

Do I need to increase my dosage to 50mg/4mg? Very confusing to be honest.
>>
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I recently measured my hips/waist/shoulders, and got 38" / 32" / 38". My height is 5'10", I'm 27 years old, and I am currently about 3 weeks into HRT. How much change can I reasonably expect from fat/muscle redistribution alone? Would it be sufficient to get a feminine figure?
>>
>>10251664

chest* not shoulders, fug. Still need to measure my shoulders desu.
>>
How gradually should one come off 100mg spiro/4mg estrofem /day
>>
>>10249795
it depends on how long since putting on the patch you did you the blood test, your levels would be lower the longer its been
>>
>>10251425
Cypro is antigonadotropic, meaning it lowers FSH and LH levels. See the first part of >>10250744 for an explanation of how cypro works.
>>
any successful shoulder workouts for ftms? Lost weight now I just need to gain muscle.
>>
>>10252176
That's too high a dose. Lower to 25mg cypro and just stay at that.
>>
>>10239388
The estrofem on ihp seems kinda expensive. Is there any place cheaper to get it or generic estradiol?
>>
So I emailed a therapist, and they told me that an HRT referral was $130 - I also emailed another one, but they haven't gotten back to me.

How much is the doctor's visit going to be? How much for the blood test? I assume I need the blood test for the prescription?
>>
>>10255313

>https://www.privatemdlabs.com/lab_tests.php?category=14&view=category_result
>Gender Reassignment
>$99.99

Is this what I'm looking for?
>>
is spiro better than cypro for femboys?
>>
>>10255313
scam

just order hrt online lol and do blood work after your first month.
>>10255902
femboys are femboys usually because of a fetish. cypro gives you tits, makes you depressed, and makes you an ace usually.
>>
>>10255912
>makes you an ace
SIGN
ME
UP
>>
>>10255923
yeah you just one day notice you don't masturbate anymore or really want to fuck
>>
>>10255912

>scam

What is? The HRT referral? My understanding was that I need to find a person with an MD who can do prescriptions and sign the informed consent form?

I'm in Washington state.

>just order hrt online lol

Don't you need a prescription for that? How do I get a prescription?

>and do blood work after your first month

So I don't need one to get a prescription? I understand why blood tests are necessary - I just need to know how flexible I can be because I'm on a budget.

>cypro gives you tits, makes you depressed, and makes you an ace usually

I've heard people say they were disappointed by their breast growth on pure estrogen, and thats why they take anti-androgens.

I'm more concerned with facial fat, but I've heard that doesn't change at all no matter what you take.
>>
>>10256044
paying $100 for a referral is a scam. you can find doctors everywhere who do informed consent and of which can get you hormones within 5 minutes. google around. my gf did informed consent in washington.

ordering hrt from places like https://www.inhousepharmacy.vu/ does not require a prescription lol. it's called self medding for a reason.

usually you do blood work prior to starting hrt and start after you get your first results, but that's if you get >legal hormones
>>
>>10255313
Dude just go to informed consent doctors. Fuck a therapist.
>>
>>10242428
>>10244049

Dr. Bisessar at Carea Community Health in Oshawa, Whitby, and Ajax [which is all within the GTA] do informed consent, Dr. VanHoof at the Durham College / UOIT clinic does informed consent, but only if you're a student, and RainbowHealthOntario [otherwise known as Sherbourne, in Toronto] does informed consent. I got HRT within 5 minutes back in 2015, and I've had a friend go to the same clinic for injection scripts and other stuff.
>>
>>10256071

>paying $100 for a referral is a scam

Yeah, seemed that way for what couldn't have been more than paperwork.

>you can find doctors everywhere who do informed consent and of which can get you hormones within 5 minutes

So if I wanted to get the prescription, I should go right to the doctor - got it.

>ordering hrt from places like https://www.inhousepharmacy.vu/ does not require a prescription lol. it's called self medding for a reason

Oh wow, really? No shipping problems?

I guess I should just save up for the blood test then, rather than a doctor? I hear they'll give you a prescription if you're already self-medding? So there's no reason to fear anyone finding out you're self-medding?

>usually you do blood work prior to starting hrt and start after you get your first results, but that's if you get >legal hormones

Can I just go total biopunk and wait until I have more money for the blood test? How dangerous is it to go without one?

Because it sounds like I can start HRT for $100. I can afford that, but nothing more.

>>10256100

I'll look into that. But the other anon is saying I don't even need the prescription?

The blood test seems more important, if I can just order the estrogen and anti-androgens.
>>
>>10255393
I always just got the female hormone panel because its cheaper and gives you all the same hormone info
>>
>>10256170
You're not paying to get a prescription, you're paying to have it monitored so you don't end up retardedly unbalanced.
>>
>>10256170
>Yeah, seemed that way for what couldn't have been more than paperwork.
ya it's just price gouging

>So if I wanted to get the prescription, I should go right to the doctor - got it.
yes

>Oh wow, really? No shipping problems?
you shouldn't have problems with inhouse or alldaychemist

> I hear they'll give you a prescription if you're already self-medding?
generally ya

>Can I just go total biopunk and wait until I have more money for the blood test? How dangerous is it to go without one?
a lot of the risks of HRT [DVT, etc] are like a 0.0000001% of the population and need to be mentioned only because it's a chance at all. i used to do blood work every 3 months but i haven't done it in 10 months because lazy.

if you're self medding you should get a job and buy in bulk in the event shortages happen. $100 is kind of low money to have.
>>
>>10256201

>a lot of the risks of HRT [DVT, etc] are like a 0.0000001% of the population and need to be mentioned only because it's a chance at all. i used to do blood work every 3 months but i haven't done it in 10 months because lazy

So having one is important to find out if you're part of that 0.0000001%?

>if you're self medding you should get a job and buy in bulk in the event shortages happen. $100 is kind of low money to have

What I meant was that I can spend $100 at a time at most. So I can't spend $500 in one week, but I can spend $100 per week for five weeks. I'd rather buy balk estrogen and anti-androgens with the money.

How long does estrogen stay good for? I've heard of people having five year supplies. I go through financial dry spells, and might need to keep a supply for 1-3 months.

How much does a 3-6 month supply cost? InhousePharmacy seems to be selling 24 25mcg patches for $32 - how long would that last me for?
>>
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>>10256243
>So having one is important to find out if you're part of that 0.0000001%?

i guess
>How long does estrogen stay good for?
idk generally they list the expiration date on the bottles. most medications that are FDA approved are safe for use even after expiration. spiro 'expires' after like 2 years or some shit.
>How much does a 3-6 month supply cost?

picture related. here in canada these are the rates for HRT, but we don't price rape unlike the US, so it could be different. i generally get 3 months of 6mg estrogen [3x2mg pills], so 270 pills, and 2 months of progesterone [1x100mg*60 pills] and 2 months of cyproterone [1x50mg*60 pills]
>InhousePharmacy seems to be selling 24 25mcg patches for $32 - how long would that last me for?

i don't know anything about patches. i just inject or take oral meds.
>>
>>10256275

>https://www.inhousepharmacy.vu/p-1313-procur-50mg-cyproterone.aspx
>Procur (Cyproterone) 50mg 50 Tablets
$1.30 per Tablet | $65.00 (USD)

>https://www.inhousepharmacy.vu/p-166-estrofem-2mg.aspx
>Estrofem (Oestradiol) 2mg (1 Pack) 28 Tablets
$1.21 per Tablet | $34.00 (USD)

The cyproterone would last me 100 days at 25mg doses, and the estrofem would last me 28 days.

The dose of estrogen you mention is higher though - 6mg - but the OP pic says to increase the dose? Does that mean 2mg is fine to start with, or would I want to take 4mg from the start and increase to 6mg?

I vaguely remember something about 2mg/day being almost useless.
>>
>>10256402
>The dose of estrogen you mention is higher though - 6mg
i take 6mg even though my doctor says i shouldn't have been given it by the other doctor in the clinic. it works so the dose hasn't changed.

>Does that mean 2mg is fine to start with, or would I want to take 4mg from the start and increase to 6mg? I vaguely remember something about 2mg/day being almost useless.

2mg is fine to be on. my gf has c cup tits and has been on 2mg for a year. your dose depends on your levels, which you'll find out from blood work.
>>
>>10256411

Awesome. I think I'll buy the drugs, then get the blood test.

Thanks muchly!
>>
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I've been on hrt for 3 months and my breasts are just starting to grow
is feeling more dysphoric a indication that I shouldn't be doing this?
my face and arms are incredibly masculine and I've got the feeling I'd just end up looking like a guy with moobs
the thing is, I've felt better these past months than I have in a long time
I think hormones make me want to kill myself a lot less and I've started to feel a little more comfortable and a lot less dissociated but I'm scared of the physical changes because I don't think I would have socially transitioned by the time I've grown breasts

should I switch to spiro from cypro instead to relieve the depression and tit-induced anxiety?
the change I'd consider the most important to me aside from mood related ones would be facial feminisaion (I don't have money for surgery though)
would taking spiro instead affect this?

half of my body has already been disfigured by testosterone (I'm 20) and I often feel like I should just go the whole way and stop transitioning but at the same time hrt has lifted the weight off my shoulders in knowing that I can't possibly get any more masc than I am already
I'm so conflicted, what do?
>>
So how do things start to feel once you up estrogen from 2 to 4mg a day? Just upped my dose today.
>>
Is it safe or effective to take low doses of both Cypro and Bica? Specifically 2mg and 25mg respectively. Not because I want to, but because that's all I've got.

If it's not good, what about taking multiple 2mg Cypro pills per day? Will that greatly increase the risk of blood clots from secondary ingredients?

Also more in general, i've been taking bica and progynova for about 9 months or so, and my chest is almost non-existant. At this point, can switching to cypro and estrofem make a difference? Or have I already fucked myself?
>>
>>10257010
I apologize this won't aid the situation, but after 3 months, how likely are people to notice your transitioning so far?
>>
Hello, does anyone have any experience ordering off of this site? It looks pretty shady but it ships here and the prices are not too bad

>http://www.shesalady.co.uk
>>
>>10258211
They're legit.
A lot of people here have ordered from them.
>>
>>10258200
not at all
>>
>>10258251
from what I've read, they ship orders and everything but they often send counterfeit meds
a few people have tested them and found them to often be the wrong chemicals altogether

personally, I'd avoid the risk and go with united pharmacies uk instead
at least they have a customer service number
>>
>>10258333
Thanks.
>>
>>10258343
>they often send counterfeit meds
Any more information available?
>>
>>10258211
>>10258251
a lot of people are saying either legit but there are also a lot of people screaming "fake"

evidence is never provided by the people saying "fake" however. It's literally nothing, which is bothersome since information is key to tell whatever what they send is fake or not

>they're selective scamming
No evidence
>the cipro is fake
No evidence
>the estrofem is fake
No evidence
>>
>>10258343
I've ordered from them once and I got what I paid for without a problem.
>>
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Hey there, I'd like to ask for some advice
Since QHI is down or w/e and I'm running low on hormones, I started looking for other places, and reading this thread I found shesalady.
Thing is, they dont sell Spiron, which I'm on. (I've been on Spiron and Estrofem for a year now) So I'm asking what will happen if I go from spiron to something else? Should I even do that, or is there a place form where I could order Spiron and Estrofem to Denmark?
Also, is there a point from which I should even change my mones to something else, or some other ways of ingesting?
>>
>>10258343
I'm afraid that united pharmacies UK don't ship here.
I would have ordered it from inhousepharmacy or alldaychemist but they do not ship here either. The only reason I am considering that website is because they apparently ship worldwide, while the other pharmas only ship to the US, Uk and several countries in Eastern Asia/The Pacifis ocean. In case you know some other good pharmas I'd like to check them out

>t. eastern european
>>
>>10258343
What specifically has been tested, and where are the results? It's the only possible option for a lot of people, so it would be nice to know if they're dangerous or not.
>>
>>10258683
What about eu-aibolit?
>>
>>10258752
Yeah, they ship here so that's good.
But why is spiro is ridiculously expensive there? A 100 piece package of 100mg spiro is 600 bucks? That's insane
>>
Went two weeks without patches but got a nice supply now. Was on 1 patch before but I wanted to up my dosage to 2 before I ran out. How long should I wait to ramp up?
>>
>>10258533
could anyone please answer? ;-; I really need help
>>
A friend of mine is starting hrt soon so I'm giving her some leftover Cypro. Would 12.5mg block t eventually? I can't really afford to send her more than like 25 50mg tablets so they'd go a lot further that way
>>
>>10261098
Probably depend on the individual.
Using 25 mg daily, my T levels do not go down.
>>
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Taking HRT alleviates my dysphoria really well, so like I'm wondering if I could use Bica on it's own? Would that be fine for medical problens? (like osteoporosis)
>>
>>10261133
25 didn't nuke it at all? I thought that was the normal dose now wtf
>>
>>10261324
Perhaps they were not on E.
Even in cancer patients they often struggle to reach castrate T levels with AAs alone which is why sometimes E is also used.
>>
so ive been on hrt about 6 months now roughly with a week or so where i was out oh hormones?
i have some questions.
i dont think ive noticed any face fat redist or any other redist except a bigger butt and gut. does that mean ill need surgery and shit to get what others get from fat redist?
i dont think my boobs are growing anymore either...

do i just keep waiting or does 6 months and no noticable change mean nah?

i switched off of spiro onto cypro after about 2 months, my hair was shedding the entire time but my hairline growing back notably. it felt like twice the shedding stopped/plateaued and lessened, after i got hrt back for the first time when i ran out and when i swtiched from spiro to cypro.

Also, i dont think cypro has gotten rid of my spiro bloat.

help?

am on barr e pills.
>>
>>10263068
also: im not sure if my tits are growing anymore or not. right one is bigger than the left and i worry about them shrinking.
>>
>>10263068
Hrts facial effects can take years but it's not like it transforms you into what you think is the perfect face.
Your nose, brow, and jaw shape will be largely unchanged. You'll get minor shifts in facial structure as you age but it's more like your body growing around existing features rather than it miraculously destroying your browline.
>>
Which gives better estradiol/estrone ratios, patches or injections? I have an appointment monday where I'm considering asking for injections instead due to them sounding more convenient, but at 3 months I'm pretty happy with the progress I've made on patches.
>>
Considering to go on HRT. Can I just take an AA but no E? if so what should I take?
>>
>>10263361
Injections
>>10264258
No. Taking an AA on its own will lead to depression in the short term and more serious health problems in the long term. Take both or don't bother.
>>
is it bad that i havent had a bloodtest and im 6 monhts in
i tried getting one but my shitty doctor didnt actually tell me my levels on it and idk how the panel test thing in the sticky works but i should read that

but i heard somewhere i shouldve had one 3 months in
idk should i be concerned?
potassium is low apparently
im on cypro though
>>
>>10259845
try out eu-aibolit anon, sorry i took a day to reply
>>
>>10239388
are people seriously taking medical advice for 4chan?
>>
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Has anyone who's on shesalady's meds gotten a blood test yet? I'm a bit worried because I feel like my sex drive got higher than it used to be when I started taking their generic cypro (compared to brand-name androcur I took previously). I may just be imagining things, but am a little nervous tbhon.
>>
>>10267812
I do my own research but everything in these threads is usually pretty accurate. People typically cite everything. So it's not really like medical advice from 4chan, you can read the citations.
>>
>>10267870
lol, why do all these doctors waste years and years learning to prescribe drugs when they can just get read 4chan
>>
>>10267906
Did you read what the person you are replying to wrote?
>>
>>10267966
you do realise that you can't take everything at face value? you have to look at drug interactions, medical history, how well the studies are received, who funded them etc. only an idiot would think they knew better than someone who had gone to medical school
>>
>>10267987
Most doctors don't study trans stuff so they're really not that knowledgeable on it.
Also drug interactions aren't difficult to figure out. Your medical history can be an issue but most people that diy have no medical issues that require doctor supervision.

Either way, no one is forcing any one to do it. If you're comfortable waiting through years of gatekeeping and aging as man just to get the same thing you'd get diying then go for it.
>>
>>10268060
lol, doctors making you wait a few years to make sure you fully understand what it means to be trans before you go ahead and mutilate your body. what are they thinking.
>>
>>10268066
There's no proof gatekeeping does anything except increase suicide rates
>>
>>10268066
People that diy WANT to transition. It's already kind of pseudo-illegal and yeah there's some risk in it. But those that do it are rarely in the questioning phase which is why they do it.

If you're not sure if you want to transition then sit in the waitlists and go through the gatekeeping. The official process is designed to weed out those that aren't sure and those that are too retarded to read a wiki page about drugs. It's an unnecessarily long and dumb process if you know you want HRT though.
Most threads I've seen on this board don't recommend questioning people to diy, they'll tell them to go to a therapist. Then if they ever stop questioning but still get gatekeeping they can diy if they like.
>>
>>10268092
Shit's gonna hit the fan when all the fake trannies and trenders who started on informed consent or DIY realize what they've done with their life. See: the wave of FtM detransitioners becoming TERFs, posts like >>10264403
>>
>>10268169
There's no informed consent where I live so I don't care if they get rid of it. Can't get rid of DIYing so not worried about that either. Not to mention most people are too retarded to diy so it's really not as common as it seems (which is why IC is so popular)
>>
so im bout to take the plunge with inhouse. does hrtgen normally get the tracking with signature or no tracking no signature?
>>
>>10261189
bump
>>
>>10267500
At 6mo is okay. It's probably long past when most up their E dosage (usually at 3mo is when you cut cypro in half and double your E).
Most people don't NEED blood tests but they're very useful and can help detect potential issues. But as you get further along in transition you only really need a blood test once a year
>>
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Oh god aibolit is down pls just be a technical error....
>>
>>10271110
>Link to database cannot be established: SQLSTATE[28000] [1045] Access denied for user 'euaiboli'@'localhost' (using password: YES)
OH GOD OH GOD OH GOD
>>
>>10271110
>>10271186
THE DAILY MAIL STRIKES AGAIN
>>
>>10271110
>>10271186
>>10271254
I wonder where the "progressive", "pro-trans" liberals, feminists and other left-wingers will be to save us this time.

Or will their support of trannies be just as nonexistent as when the Daily Terf shit down QHI?
>>
So any good sites for MtF HRT for the US? Also if anyone has experience would they be able to tell me typical shipping time? Trying to transition soon starting with self-medding (doctor is not an option for the next half a year or so). Any info at all is appreciated, not too knowledgable in any of this.
>>
>>10271275
>expecting feminists to care about trans people
I know you're joking but the silence is deafening.
>>
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ugh i fucking love patches my levels are on point
>>
>>10271495
Why would you expect them to care? Most feminists don't even want to be women.
>>
>>10271544
>1471 pmol/L
Are you pregnant?
>>
>>10271553
and thats my levels on 2 100mcg patches twice per week without any testosterone blocker! its nuts
>>
>>10271561
just so you know 100 much E is also a bad thing
>>
>>10271572
Please present your evidence.
>>
>>10271572
i think my levels peaked the day i was tested because ive been on this hrt regimen for a year and my levels have never been this high. the only difference is im no longer on triptorelin as my t- blocker
>>
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Aibolit is back; it was just a technical issue!
>>
>>10271110
>>10271772
They just sent the tracking code for my shipment, 9 days after payment confirmation.
>>
>>10271431
Try inhousepharmacy.vu
shipping time is about 1-2 weeks, sometimes 3
>>
>>10268596
Either option is fine. A package requiring a signature is just an extra security step if you don’t want someone stealing your package
>>
When should I go to get my blood tests done? In the morning before I take my estrogen?
>>
>>10271910
Tyvm anon
>>
>>10271990
Yes, in the morning before your next dose.
In the lab where I making my tests, they told me that for getting accurate T levels, I should go between 7 am to 10 am
>>
i switched to cypro 2 weeks ago and now my hair is shedding
i woke up and ran my fingers through my hair a few times and got like 50 strands

cypro 50mg
e 4mg
>>
>>10272133
it's not happening in mpb areas (hairline and such), but it is a lot of hair falling out.
>>
>>10272133
>>10272146
it might just be new hair pushing out the old. typically happens with hair loss treatment such as finasteride or minoxidil. I wouldn’t worry about it unless it continues for more than a week or you start noticing thinning
>>
>>10239388
Someone redpill me on alcohol and hrt.
I've been drinking quite a bit lately while on hrt and don't wanna kill my liver.
>>
>>10272221
Depends on your health and diet as well, how much and of what you drink, i'm a regular drinker, been on cypro for over 2 years, i remember downing it with vodka once as a celebration, no symptoms of any problems so far
>>
>>10272526
I'm on a relatively low dose of hrt right now (i. e. 2mg E and cypro) and I've been drinking maybe 3 beers every 2-3 days for a while.
I'm also on SSNRIs, finasteride, beta blockers and the occasional benzo pill.
I'm worried all that might be a bit stressful for my liver.
>>
i'm on 8mg Progynova (orally) a a day yet i have 208 pmol/L on my latest blood test with the lab's provided range for the Follicular stage as: 98-571pmol/L
Should i up the dosage? Change the intake method?
>>
>>10272582
>I'm on a relatively low dose of hrt right now (i. e. 2mg E and cypro) and I've been drinking maybe 3 beers every 2-3 days for a while.
Probably fine, if you were doing liver damage you would probably know, i think one symptom i experienced was hangovers just got much worse for me, but that disappeared when i started to drink lighter drinks like white wine and cider instead of whiskey and rum, if you're paranoid, or have reason to be suspicious, you should get tested
>I'm also on SSNRIs, finasteride, beta blockers and the occasional benzo pill.
no idea what any of these are except finasteride but most pills taken orally will have some kind of impact regardless of what's in them, so be careful
>>
>>10272999
That's a pretty high dosage and not much E2... Your estrone levels are probably insane.
You should take it sublingually
>>
>>10273097
Thanks, i've been on this dosage for 2 years and just had my first blood test a few days ago, so i'll do that, but taking 4 pills sublingually is gonna be quite a task, is there any guide on how to do this? A technique? I wanna make sure i do it correctly as well.
What's estrone?
>>
>>10273119
You should be splitting your dosages. Plus I doubt you'd need 8mg if on sublingual. Probably a 2/2/2 split would be fine.
Estrone is the metabolite of estradiol. It can potentially interfere with estradiols effects but its purpose isn't fully known. It's sometimes thought of as a longterm storage for E2 but there's been some studies suggesting you get better feminization if your E2:E1 ratio are closer to cis ratios
>>
>>10273136
I am, 2 in the morning and 2 in the evening but idk
but how does taking Progy in a certain way affect how much E2 and E1 there is?
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>>10273148
Sublingual, patches, injections, and transdermal skip first pass metabolism.
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>>10273154
so it doesn't get turned into E1 and instead gets turned into E2? Gotcha
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>>10273154
wait, isn't progynova only meant to be taken orally?
>>
How to take pills sublingually?
Do you put it under the tongue and keep it there and just swallow the saliva until it dissolves?
>>
>>10273922
Don't let saliva under your tongue. If everything goes okay there will be little to none liquid after the pills has been dissolved
>>
>>10267839
I dunno, I'm taking 25mg a day, at night, of androcur from united pharmacy and i've morning boners and wet dreams for the first time in years and I'm not getting depressed, been a week and a half so far.
>>
>>10273982
I don't think that's even possible, in 2 minutes it's a swimming pool in there and i don't understand what you'd do with it other than swallow, am i just supposed to wait until the pill dissolves before swallowing it? do i spit it out?
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>>10273097
Can this be caused by nicotine?
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>>10273982
Isn't the whole idea: pill dissolves in saliva -> E goes from saliva into skin pores, from there into bloodstream?

>>10274104
I keep the pill + saliva in my mouth for like 30-40 minutes typically, and after that spit it out.
>>
I've been on hrt for 5 days now with just 100mg of spiro. Should I up my dose? When do I add in e? (Switching to cypro in august btw if I stick with transitioning)
>>
>>10274303
holy shit why so long? and why not swallow it?
>>
>>10274303
>I keep the pill + saliva in my mouth for like 30-40 minutes typically, and after that spit it out.
how? and how do you not swallow for so long?
>>
I dont understand what im supposed to be expecting

I’m a guy body at 25 that atarted a week ago and already i’m noticing smooth skin and a filling ass and rounding chest (had a bit of manboob when starting)

Should i be expecting these changesbso soon?

Also i started 25mg cypro and 2mg estradiol but that was really shittybso i upped to 4mg estradiol pretty soon after
>>
>>10274489
I've read that the longer you keep it in your mouth, the higher the efficacy.

>>10274500
Uh, just don't swallow? I never found it that difficult.
>>
>>10274574
>just don't swallow
and just have a mouth that's full of saliva for half an hour?
>>
>>10274610
Yep! If you can't do it because you're at work or whatever, try doing buccal instead.
>>
>>10274637
and you do this with estrofem, correct? or Progynova?
>>
>>10274648
Estrofem, yeah.
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>>10274668
i see, i guess i'll switch to sublingual when my progynova supply runs out, and try to quit smoking in the meantime. thanks
>>
>>10274399
Spiro dose is good and most people start e and the aa at the same time
>>
>>10273753
Progy can be done sublingually. Lots of people have posted blood tests as proof.
>>
>>10274104
Sublingual needs to be dissolved by saliva in order to absorb. Let the pill dissolve then swirl your saliva around for 5mins or so.
Don't eat/drink for 15-20mins afterward either, it decreases the absorption since much of it is just trapped in the folds of your mucous membrane and eating/drinking will wash it away.
>>
Are patches better than taking oral estradiol? I'm getting my first official script in a few weeks and I'm not sure which to ask for, she said most people don't like patches because they're annoying but isn't the absorption better?
>>
>>10275800
Patches are better than pills, with injections being the best.
>>
Canacucks fucked with my hormone meds, now I'm so dead inside all I think about is destroying the human race.
>>
Where is the best place for placing estradot patches?
I have read that the femoral triangle is the most effective way, is this true?
>>
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Hey so could do with some advice. I was on HRT (2mg E 25mg bica) for 6 weeks before I stopped for a month (had to stop to produce useable sperm samples to freeze). I was going to go up to 4mg had I not had to stop, but I don't know how the fact I took a month out will affect things.

When I restart my HRT, should I act as though I'm starting from the beginning? Also, does anyone know if this month-long gap will have any negative effects on my development?
>>
>>10277336
>(had to stop to produce useable sperm samples to freeze)
I will never understand this.
>When I restart my HRT, should I act as though I'm starting from the beginning?
I don't think there's any scientific evidence that starting with low doses and slowly increasing is actually beneficial. Doctors only do it to mimic cis female puberty.
>Also, does anyone know if this month-long gap will have any negative effects on my development?
To answer your question literally: no. To answer the implied question: it's unlikely to have any negative effect.
>>
>>10277369
From my understanding doctors taper upward for health reasons predominantly. They don't care that much about feminization they're mostly worried about your health.

But yeah once you're healthy and levels are good there's no proof high E2 hinders anything. Even the E2:E1 study has never been replicated and it's not even fully understood what E1 does in humans either.
>>
I've been thinking of taking hrt for at least two years now so at the very least its something I really want to do

But I just saw this thread >>10267889

Idk anons

should I start hrt? I am 21 now

How long will it take for the effects to be evident? (breast development, change in fat distribution, etc)

At what point would someone be rendered sterile?

Is 21 too old?
>>
>>10277369
>I will never understand this.
Well basically I wanted to store some samples but I had an analysis and my sperm quality was quite poor so I have to take some fertility supplements and stop the HRT for a bit to improve the quality of the sample I provide
>>
>>10277405
>should I start hrt? I am 21 now
Only you can decide but you've been thinking about it for 2 years so you're probably trans

>How long will it take for the effects to be evident? (breast development, change in fat distribution, etc)
Breast budding starts after like a month

>At what point would someone be rendered sterile?
About 6 months

>Is 21 too old?
Too old to pass? No. Too old to transition? Also no.
>>
>>10277431
>21
>not too old to pass
ha
>>
>>10277464
t. Youngshit
>>
Started HRT with 50mg cypro, stayed on it for a year and a half, my T level was consistently 14 ng/dl give or take
Recently switched to 25mg, my T level was 22 ng/dl when I last tested
Should I go down to 12.5 now? would that be smart?

I ask this because my sex drive has been completely dead recently, I haven't gotten horny in days. It might just be stress, but it's weird.
>>
>>10278578
Yes go down to 12.5 mg. You may not even need an AA at this point, honestly. Your T would probably be sufficiently suppressed by E. What dose do you take?
>>
>>10240054
>>10240313
does anyone know where yu can get bloodtests done in the netherlands or belgium? i'm about to start with cypro and estrofem but would prefer to have a base-line test.
>>
Bit of a weird one, but did any of you start getting a runny nose when you started HRT? It's been happening to me, especially when eating, and this NHS page suggests it might be related to hormones https://www.nhs.uk/conditions/non-allergic-rhinitis/causes/#hormonal-imbalance

?
>>
>>10239388
can hrt cause hair growth?
i had actually zero bodyhair before i started (removed years ago) and now i see vellus hairs starting to grow everywhere like on my fingers and pubes
im 6 months in
>>
Any worries if i'm going to remove 3 wisdom teeth while on hrt?

Can't exactly trust to tell my doctor because he is my uncle and family doesn't knows i'm on hrt. Currently on 3mg sublingual/day + 12.5mg cyproterone/day.
>>
People say 12.5mg cypro sounds too low to nuke my T and i'm getting scared. I didn't had a blood test at my current dosage yet.
I was on 25mg cypro with 2mg estrogen for some months, and my T level was 3ng/dl. Decreased cypro to 12.5mg and increased estrogen to 4mg a month ago. Am i theoretically safe?
>>
>>10280593
On paper it sounds good, but get the blood test to be sure
>>
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>>10261189
bump two, I read some studies about bica monotherapy in prostate cancer but from what I gathered it just dealt with the cancer, not about future health risks from potentially low hormones.
>>
>>10280483
If you aren't a 40 year old smoking hon you'll be fine.
>>
>>10279531
I take 5mg E every two weeks, or 10mg per month.
The same bloodtest gave me an E level of 70 pg/ml
>>
so qhi never recovered? for those in uk how many days does unitedpharmacy take to deliver?
>>
>>10280483
>Can't exactly trust to tell my doctor because he is my uncle
I'm surprised how common this kind of thing is. It seems to come up every few threads.
>>
>>10280483
Stop taking AAs for about 4-5days beforehand. The E doesn't matter. Just in case they use anesthetic and there's drug interactions
>>
>>10239388
My T is nuked

Why do I have to cum like twice a day
>>
How do I stop my belly getting fat I wanted my ass to get fat not my belly come on HRT doesn't work
>>
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Should I worry about DHT if I take 100mgs of Bicalutamide and 5mgs estradiol daily?
>>
>>10283324
No. Why are you taking so much bicalutamide?
>>
I want to try HRT. How long does it take to cause irreversible infertility?
>>
>>10283427
Because I was some having pimples and some chin hairs when I took 50, now on 100 I do not. And no I'm not some hulking manbeast , I'm a skinny twinkhon , so idk. But I'll be damned if I allow testosterone to rape me one iota further.
>>
>>10283448
>Because I was some having pimples and some chin hairs when I took 50, now on 100 I do not.
Eh, whatever works. Consider getting a blood test to see where your testosterone levels are at.
>>
>>10283439
Nobody knows~
>>
>>10283561
I was under the impression blood tests don't work for Bicalutamide the way they work for the standard Cypro or Spiro
>>
>>10283669
Estradiol lowers testosterone levels.
>>
>>10283439
6 months
>>
>shesalady
Anybody know what AA's does shesalady currently have available? I'm pretty sure the listing on the website isn't up to date.
Anybody know if she's got spiro or bica?
>>
>>10283919
>spiro
but why
>>
anybody know if this is legit

http://eu-aibolit.com/onkologiya/23642-bikalutamid-kanon-bicalutamide-canon-bicalutamide-tabletki-50-mg-30-sht.html?search_query=bicalutamide&results=11
>>
Can anyone advise me on where to go? Currently going on .2mg patches with two 50mg spiro but I still got lots of nasty body hair but my levels are great. I can diy a few months of cypro so should I do it?
>>
>>10282939
Because your sexuality is reorganized to run on E instead of T? In my case, during the first weeks on cypro my sex drive was completely dead, but after a while it came back. I have more intense orgasms now than I had before starting HRT, although I only ejaculate small watery puddles at this point.
>>
Is it bad to be taking 4mg estrofem at 4 months HRT? Would there be any benefit in halving my dose?
>>
>>10284289
It's a normal dose. By halving your dose you mean taking 2 mg twice every day?
>>
>>10284340
No i mean taking 2mg a day.
I've just noticed everyone seems to only take 2mg, perhaps they'll be on 4mg after a year hrt but never this early and got worried.
>>
>>10284350
2 mg is a too low dose, it's unlikely you will get female E levels on it. It's normal to take 4-6 mg after 4 months. Anyways, you should check your levels if you have the possibility
>>
>>10239740
So Why is ethinylestradiol so bad? It's the active ingredient in estrofem, which I havn't heard anything bad about?
>>
>>10284379
The active ingredient of estrofem is estradiol, ethinylestradiol is usually found in birth control pills.
It's not recommended because of elevated risk of blood clots and liver damage. Estrofem (bioidentical estradiol) is safe and commonly used for HRT.
>>
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>>10284413
Not according to united pharmacies
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>>10284437
United Pharmacies want to kill us all and then ban HRT. Based
>>
>>10284437
Look at the packaging, "Oestradiol (as hemihydrate)"
>>
Does anyone here take cordyceps with anti-androgens? It's a chinese mushroom that's really good for the kidneys and other things, but it has also been shown to raise t levels. I've had great results from it when buying from a good source. It might ease the strain that spiro has on the kidneys. I haven't taken it since starting hrt though.
I wouldn't want it to impede my progress, but on the other hand, it might be useful at retaining penile function and sperm production. I always noticed that it positively affected those things. I'm not sure if this effect is caused by increased t, or vice versa. In the latter case, you might be able to take a higher dose of spiro to counter the increased t while still having improved functioning down there
>>
>>10284699
I've used cordyceps and reishi extracts and I've never noticed any effect on hormones.
>>
>>10284977
Reishi doesn't seem to affect my hormones much, but cordyceps usually gives me an instant boner
>>
I really like the idea of large, fully-functioning breasts
Anyone here use a breast pump? I was thinking of getting one to help chest development
>>
>>10284437
wooooow
and people trust their health to this company
>>
Anyone order anything from chemistshop365?

They seem to have injectables in bulk
>>
>>10285004
Shouldn't do that much. Are you taking an extract?
>>
>>10285603
Yeah it's a 10:1 extract
>>
>>10285846
Of what? Water or nonpolar fraction?
>>
could i still be fertile 5 months in?
>>
>>10285853
"It is a dual water/ethanol extract, which allows for the concentration of both water and ethanol soluble compounds. Hot water is still used to break down the chitin. However, then ethanol is also used. In this extract, 10 units of starting mushroom are used to make 1 unit of finished extract. In contrast to our 1:1, the 10:1 concentrates the water/ethanol soluble compounds, and discards the rest"
>>
>>10285911
Yeah some of the nonpolar compounds in cordyceps modulate nitric oxide response. It may allow erections due to that, not necessarily due to T.
I'm on cypro/E and my T is completely nuked but I have zero erectile dysfunction. I don't get nocturnal erections and I have no semen but my penis is 100% functional otherwise.
>>
What up with the eu-abolit website? I tried to order some stuff from it, but the account registration form doesn't work, nor does the "order without registration" option at checkout.
I also tried to send them a ticket/message thing, but that gave me an error too

Is the website totally broken?
>>
>>10286070
What's up*
>>
>>10286070
I ordered from them about a month ago and everything went fine; their meds are legit too. Dunno if they're having technical issues or something.
>>
Are low levels of E better at feminizing than high levels of E on MTFs I've read already so many anecdotes of people having low levels of E and having great results.
>>
>>10286700
Cool. Yeah, hopefully it's just a temporary thing

I sent them an email too, but I don't know if they speak english or not
I'll keep you guys posted if they reply
>>
I sent an email to shesalady a week ago and didn't get a response...
>>
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>>10287182
what
>>
>>10287237
I sent them an email asking what they needed by way of bank details, what types of payment they accepted, and how to deal with customs issues if there were any, as well as what exactly was is the t-girl starter pack and what the expiry dates they had on them, and didn't get a response
>>
>>10287252
they're probably just a bit overloaded or something

that sounds like a lot to respond to though. I find that keeping it brief with the emails usually helps with getting a response quickly
>>
new thread, kids
>>10287441
>>10287441
>>10287441
>>10287441




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