This guy doesnt look any younger. The grifter said five years ago he'd look 18 by now. I guess the whole "anti aging" science thing was a scam.>inb4 that one schizo who spams pharma stuff and claims to look younger but never posts pics shits up the threaddude please dont
>>77318216you can attempt to slow it down, live long without being ill, and even mask an aging appearance, but no living mammal can defy aging. you will age. you will die. he's nothing more than a content creator and health/disease prevention promotor. at least he's selling something and found a young gf he feels like he can trust out of it.
>>77318216youthmaxxing can't make you look younger only gayer
Yes it's late stage mice utopia experiment manifestations. People who unironically think they can cheat biology and be stuck in highschool forever. It's ironic that he's stressing himself over this to the point where he doesn't even go outside anymore without his 200 creams and umbrella and glasses and layers of clothes when just taking a trip to some mediteranean island, or hell just live there dude he has the money for it, would do his longevity and health better than the torment he's going through
He looks dreadful.
>>77318216Honestly, I'm kinda rooting for himSure 99% of his lifestyle is gonna accumulate to absolutely nothing, but he is being very transparent with his journey
>>77318308He's not transparent about anything, he lies about almost everything, im talking "photoshops test results and blocks anyone who brings it up" tier lies, hes a total fag
>>77318216you can attempt to slow it down, live long without being ill, and even mask an aging appearance, but no living mammal can defy aging. you will age. you will die.he's nothing more than a content creator and health/disease prevention promotor. at least he's selling something and found a young gf he feels like he can trust out of it.
>>77318308He has been couggt faking his tests. Thay was after he was called out on not publishing all data. He is a fraudster. Nothing much.
I'm 39 this year. I have both sets of grand parents still in their mid/late 90s. I'm gonna outlive this vampire eating burgers and pizza lol
>>77318216Why is he not 'pale' but yellow-grey?
>>77318216I think that every time people embark on a minmaxxing journey like that, they eventually realize that only a few (already known) things REALLY matter and have a high impact or ROI, and it all comes down to the 80/20 Rule
>>77318216>>inb4 that one schizo who spams pharma stuff and claims to look younger but never posts pics shits up the thread>dude please dontBreh, research some real chemical peels stronger than Bryan's Vitamin C and then tell me this anti-aging shit all fake.>t. way out-biosharts the walled grifter
>>77318350"Promethean tan"
>>77318348wow, that's 4 funerals stacked in short term. grand slam vacation.
Was his mistake getting an erection? Because that's the biggest sauna mistake.
>>77318383 Post body
>>77318396Desu being drunk and stumbling onto the stove or passing out and dying can be a pretty big mistakes too.
This man is severely mentally ill and he should not have a platform. The dude injects his son's own blood into himself, He has to take both testosterone and estrogen because his body fat is so low and he's so emaciated because he eats so little and his body won't produce it naturally anymore, And he's literally so weak that he had to leave a country because his body couldn't process the dust in the air.
>>77318308>he is being very transparent with his journeyI, too, believe self-reported results and practices of individuals on the internet with no independent review of the facts whatsoever, my fellow intelligent and totally not gullible poster.
We're not gonna make much progress on that front until we crack nano machines and genetic editing
Listen and learn, heretics.https://www.youtube.com/watch?v=_L-pjxsd2HU
He just looks uncanny. People have forgotten how to just age gracefully.
My mom got mad at me cause I told her she's old at age 55.
>>77318350vegan gaunt
>>77318245Naked mole-rat would like a word.
>>77318216Jesus, he looks like a fucking corpse
>>77318216he looks his age despite the thousands of dollars he used to reverse his aging he wasted his money
>>77318216He said himself that 90% of all of it depends on your genes.
>>77318216Bruh looks like a corpse they smothered in make up
>>77318937i would argue ethnicity and race are contributing factorsif you are asian you are going to look younger than people of other racesi think even black people age better than white peoplepic-related
>>77318216Who's the Old Man in your picture OP?
>>77318944Nope you're just faceblind, it's an inside joke/unspoken-forbidden rule within asians to confuse people with their looks when they actually look other to each other considering how unhealthy they are usuallyFactor in plastic surgeries culture alsoThere's 0 reason a subgroup of humans would develop a supposed neoteny gene sequence out of everyone else
>>77318954
>>77318216He started too late, the people who started earlier are doing much better. Still, there is no actual anti aging therapies. The best you can aim for is to slow it down to nearly half. The whole idea is to stay as young as possible while new therapies start to become available.The only thing that is stupid is to spend so much money and taking a hundred pills. Most of it is about good sleep, diet and exercise. That accounts for 90% of what this dude does without spending a penny. It's okay to take vitamins or minerals that you are deficient in or that you are not covering with your diet, but chocking on 9000 anti oxidants at the same time doesn't seem to be a smart way to address the issue. At some point it stops helping and might actually be harmful.Most things that are labeled as antiaging is because they block mTor or activate autophagy and you see him taking these after exercise. Sometimes he mixes stuff without caring about interactions or if these compete for absorption with each other. Just watching him take pills that activate Ampk along with protein in order to trigger an anabolic response makes me raise a lot of question.He is a great salesman though.
>>77318960Now do that without makeup, photoshop, bad lighting, history of drug use, surgeries etcThis is just proving my argument, you wont find two people of the same age same physical condition and diet and substance use history with different appearance outcome when it comes to aging
>>77318964emma watson is wearing make up and she still looks awful
>>77318350it's a thing with vegans, especially older ones, where they have a really weird, unnatural looking skin tone
>>77318966Love how you didnt address any other point. I accept your concession
>>77318216/fit/ has the entirely wrong idea about this guy.It's not about looking younger, it's about having the health metrics of a younger person.It checks out that a board full of looks-obsessed bodybuilders would be unable to grasp the idea of doing anything for your health.
>>77318984He's my favorite vampyre.
>>77318960British women age like shit, that is nothing new.
>>77319002British Women age just fine with a little cushion they aren't meant to be skeletons.
>>77318984Does he look healthy to you?
>>77319023kek, like clockwork
>>77318398No, but I did frame-mog several hundred people shopping at a sporting goods store today, so I don't really need ur validation.>>77318427He quit the test and blood injections, but otherwise yeah. He also stupidly took and quit Rapamycin which you forgot. Doesn't make all his interventions fake, but many are.>>77318963>Still, there is no actual anti aging therapies. The best you can aim for is to slow it down to nearly half.Lel that's contradictory, but nematode evidence already says we might be able to do 80% or more.>The only thing that is stupid is to spend so much money and taking a hundred pills.Yeah, he gets massively ripped off, but he's ack-shilly not even on that many pills; I am.
>>77318970As a neutral observer, you won the argument
>>77318949Bro, 37-year-old Brazilians are just doin' 2 much now. Picrel.
>>77318944Asian diet is low in vitamin A poisoning and low in obesity - both those two things can contribute to aging well. The fat and liver in elderly people is a sickly yellow due to vitamin A accumulation, and vitamin A excess is highly implicated in liver damage as well as its known effects of destroying collagen
Dude is just ugly, being healthy won't improve being ugly, he needs surgery
>>77318984>skin of a 35 year old vampire woman who visits the spa>heart of a 75 year old who took the vaccineHealth fails at the weakest point
>>77319260Nah he would be decent looking if he ate beef daily, got a nice tan, and lifted some weights (not retarded calisthenics stuff)The veganism + vampire sun avoidance + female skincare treatments just make him look weird
>>77319259>low in vitamin A poisoningSo is every diet on earth, including inuits
>>77319125>, so I don't really need ur validation.Yup which is why you post about it every single hour you useless indian
>>77319274Its really not when you look at the levels of vitamin A in the liver of western people, and like 75% have unsafe levels.
>>77318216he might have said he would have the biological markers of an 18 year old, not that hed look like one
>>77318826youre a shitty son, my moms 69 and Ive never called her old
>>77318944Sun exposure ages skin more visibly. Asians have a culture of less sun exposure, since whiter skin is associated with better attractiveness (people who work outside are considered lower class). Black people have more melanin (i.e. they're black) and are less susceptible to skin damage because of this.Additionally, Black and Asian skin types have a thicker, more compact dermis, which is naturally more resistant to sagging, and their skin naturally contains denser collagen bundles and thicker fibroblasts, making it naturally firmer and slower to break down with age.
>>77319125>Which you forgot.God forbid I'm not completely up to date and thoroughly researched and versed in every single pill this guy pops into his mouth.
>>77318216I've never seen such a young man.
>>77319720It's not even that challenging because he barely updates his protocol anymore. I'm trying to get better-versed in all the shit he should be on if he knew what the fuck he were doing a bit moar.
>>77319765>It's not hard to pour sand in your coffee, therefore you should do it.Flowless logic.
>>77319765Post body
>>77319765If you want to know what that dude is doing, check out his posts section on youtube.https://www.youtube.com/@BryanJohnson/posts
>>77319773His Xitter and site have more info on his protocol though, albeit you gotta pay $1M/year to get *all* his data.
>replying to yourself
>>77319773He's seriously mentally ill, listened to his voice for the first time when they brought him in the enhanced games to explain why steroids make you stronger and god he has such a nasally "punch me so i can cry to a teacher" voice
>>77319779Post body
>>77318216Actually solving aging requires investment and effort on the scale of the Manhattan Project. He's just doing expensive bullshit for rich people.
>>77318216This guy looks like fucking Nosferatu.
>>77319835>Actually solving aging requires investment and effort on the scale of the Manhattan Project. He's just doing expensive bullshit for rich people.To be fair though, he's on GlyNAC and Astaxanthin which were hits from the NIH ITP; current closest thing to a "Manhattan Project" for anti-aging.>t. started on NAC b4 ITP figured out it worked, never fux'd w/ rapamycin but hit many of the same targets it does using other non-rapalog stuff
>>77319859I think you're being extremely generous. He acts as if he's solving the problem and leading the movement, whereas really he's only incorporating things from the people who are actually doing something consequential. Secondly, NIH ITP is still peanuts. It needs Manhattan Project/Apollo Program levels of funding and coordination.
>>77318216Youthmaxxing can work but he's doing it wrong. For starters, listen to reality instead of studies.
>>77318256>mice utopia experimentIQ 89 take, mouse utopia is not at all comparable to modern life in the west.>no free resources>no inability to leave>no overpopulation>no protection from disease and predators, quite the opposite actuallyWe're living in a dystopia, not an utopia.
We need more immortal scientists.
>>77318216He looks like the android from Aliens.
>>77318216This is a real comment chain.
>>77319984hunterposting is the funniest fucking thing that dogshit website has seen since trump stopped posting there
>>77319918It's funny that you say that because they had a hysterical group complaining no matter what. To any observer from the outside westoids are all whiny bitches
>>77318216I worked directly under Johnson for about 4 years. Can't say in what capacity because literally every employee of his signs air tight NDAs. Here's what I can tell you>total bro, loves a good, racist joke>was a /b/tard for several years until they all migrated to /pol/>he hates politicians but loves their money so he never says his political views out loud>he truly believes in his products and services and his goal is to live to the year 2150>he hates the sun and believes it's one of the main causes of aging>he won't sell his Blueprint to employees yet because nobody has $10m for the "platinum" tier (workshopping tier names still) but he thinks by 2030, he will have a $50k "executive" package ready for market As far as him faking test results, I dont know anything about that. I dont think he would based on what I know about him. Hell, he had his employees measuring his nighttime erections lol.
>>77318256People aren't mice
>>77320477he seems nice enough but sometimes I do get the impression of narcissistic tendencies
>>77319835Anybody who sees aging as a problem that can be "solved" are just as bad as trannies.
>>77320477>but he thinks by 2030, he will have a $50k "executive" package ready for marketI can do that with over 500 molecules by 2028.
>>77320577Post body
>>77320477>>total bro, loves a good, racist joke>>was a /b/tard for several years until they all migrated to /pol/>>he hates politicians but loves their money so he never says his political views out loudSounds like you're either a fanboy doing damage control if not himself or his pr team. Why do you care about this shitholes opinion so much you need to portray him as le heckin based racist. It doesn't change the fact that he's a con artist and weirdo
>>77318944blacks don't suffer UV damage to their skin the way Whites do. They are genetically evolved over millions of years to live in places where the sun is very strong while Whites are genetically evolved over millions of years to live in places where the sun is very weak.Putting a White in a sunny place will lead to skin damage just like putting a black in civilized society will lead to him freaking out and trying to kill everyone in a panic.
>>77318216>hates the sunSo he is a vampire.
>>77318216He looks like a Synth
>>77318216Hes monitoring his internal biomarkers for age not how fuckable and young he looks
>>77320615CAN be, usually aren't though.Meanwhile blacks...
>>77318216he looks like a dead body
>>77318216He looks like he's already embalmed lmao
>>77320614What's the point of aging slower and having youthful biomarkers or whatever if it requires your entire life to revolve around a bunch of gay bullshit and rituals to maintain it? The great thing about being actually youthful is the freedom, you don't have to care about all that tedious shit, you just live your life. He'll never regain youthfulness in that sense, and really, it's the only one that actually matters.What a wasted life.
>>77320477ehh dude he measures his own sons boners and posed in some weird gay erotic photoshoot with his dad and son, I dont believe hes anything but a hard lefty much less racist
>>77320827You're just jealous your dad didn't do such things with you.
>>77320844
>>77318245Chagpt post
>>77320893Go outside bro
>>77318216It's really hard to reverse aging once it has occured. Might be interesting to see BJ try out the Yamanaka factors but we know he won't because this grifter doesn't try anything he can't sell.>>77318245>but no living mammal can defy aging.Naked mole rats already do. The only reason they die is because they all kill each other.
>>77318937And he's wrong. Not dying nowadays means watching your cholesterol values and driving it below certain levels. Genetics are only relevant after that.
>>77319859GLYNAC hasn't been tested by the ITP and chances are it does next to nothing. Astaxanthin only also barely worked in male mice at super high doses but not at moderate doses, making it useless for lifespan extension.Rapamycin only works when taken daily at high doses, making it useless in the real world. SGLT2 inhibitors are definitely healthy but only useful if you have higher blood sugar. Then there are non-feminizing estrogens which most likely work because they significantly inhibit DHT.
Ahahha holy shit lmaoo
>>77321012ZUUN HAL VIIK
>>77321012What a good looking 15 year old.
>>77321012So fucking pale, nigga needs to get some damn sun.
>>77321037THE SUN KILLS YOU
>>77318216Commander Data lookin ass
I can't get over the "no sun no exceptions" thing. Our minds, over countless eons, have been hard-coded to detect signs of health and signs of sickliness. His palid skin looks absolutely sickly. You can't tell me zero sun exposure is good for you
>>77321043UV light does absolutely destroy your skin but as long as you wear your sunscreen and take some carotenoids being in the sun is fine.
Reminder that he's a former mormon. Mormons believe they can ascend to literal godhood. There's no way his goal of achieving biological immortality doesn't ultimately stem from his kooky mormon beliefs.
>>77321049Sure but to what extent? Is it really the case that any form of natural gentle tanning is bad? I don't think that's true. If it were, then why do we inherently see his sickly Data looking ass as being unnatural and unhealthy and unattractive?I'm not saying people shouldn't use sunscreen and should roast in the sun and turn themselves into baked potatoes. But I have a hard time believing zero sun exposure is optimal
>>77321058Tanning indicates some damage has occured.>If it were, then why do we inherently see his sickly Data looking ass as being unnatural and unhealthy and unattractive?We do but we also see people with leathery skin as old. There is a reason why people look into different ways to get a tan like beta carotene.>But I have a hard time believing zero sun exposure is optimalRemove UV from the spectrum and sunlight is beneficial for health.
>>77321058He's trying to look as young as possible, not naturally healthy. Tans do look good naturally, but in nature, your reproducing days would be done at 21, and it doesnt matter if you look like a ballsack, tanned or not, at 30, because you've only got a decade left to live. He'd look "better" with a tan, but its more important he look "younger" by avoiding any possible UV damage. He wants to look like a sickly teenager, he knows looking like a healthy tanned teenager ain't ever in the cards for him
>>77321136Having a slight red haze indicates you're healthy, sun exposure helps in blood circulation >>77321065Nope UV is good. Vitamin D and serotonin
Strange that goatis hasn't aged a day in the last decade, faceIQ hasn't aged at all but got one (ONE) pimple and had a crashout saying he was ruined and ugly because said problem was so rare for him, when you look at the natural human diet enjoyers they haven't aged a day this decade but this guy just always looks strange and sickly.>>77318984Sexual virility is a marker for healthLooks are a market for healthFeeling healthy is a marker for healthPeople like to pretend they can ignore all 3 of these and just have "lab tests" or whatever. If you're ugly you're unhealthy. Looking old means you're aged.
Imagine wasting your life trying to pretend you have more life. Genuine clown behavior.
>>77321012
>>77321043>Sun pretty much universally feels good to animals and plants (as long as it's not harsh sun on a hot day)>Sun also regulates melatonin, the greatest antioxidant to ever exist>But he doesn't get sun Yeah it's over for him. Stress is the number one thing that ages you and no sun is massively stressing his body, plus you synthesize a ton of nutrients from the sunlight hitting bare exposed skin so his "markers" are good based on a bunch of unscientific guesses but he's entirely off in anything that your body synthesizes from sun exposure.In the past when people were in poor health they were sent to the sea or countryside to get lots of sun, relaxation, and fresh air.
>>77321136>in nature, your reproducing days would be done at 21In nature you'd have 8-10 kids, actually that was just life as a farmer 50 years ago, in nature you'd have 10+ (basically as many as your wife could have until she stopped having them or died)>You'd only have 10 year left of lifeHow can anyone actually believe this still?
>>77321163>Sexual virility is a marker for health Wait until you hear about his nighttime erections and the microplastics count in his sperm.
>>77318984I think this isn't true, and the way he broadcasts himself demonstrates the point. If the focus was in biological age, he would focus purely on organ function. Brain scans, cardiac output and other hemodynamic data, glomecular filtration rate, liver function tests, etc.But instead, its all about hair transplants and dutasteride scalp injections, or staying out of the sun to reduce wrinkles, dyeing his gray hairs, and other things that are just cargo cult bullshit to give the superficial outward appearance of looking younger
>>77321184>actually that was just life as a farmer 50 years agokek
>>77321184Pic rel is what farming looked like 50 years ago, in June 1976.
>>77318216Maybe it's the picture but he gives me 'android from Aliens' vibe
>>77321264IYKYK, I grew up hearing the AG stories of the time.Small cattle was basically phased out gradually from that time forward, so now you have decaying barns and infrastructure. Cattle herd sizes went from 50 to 100 to 1,000, 50 years ago small cattle farms were just outright common and were everywhere but too much milk was being produced and the government started buying them out.For orchards it was a little different, you didn't have dwarf trees in our area so they're climbing 20-30 feet up a ladder to pick apples, for example. Many kids who lived on said farms had to pick before and after school just to get by, if you were a kid on a farm you were expected to work.But yeah grain farms have been mechanized for a long time. Dairy and fruit weren't, and fruit largely still isn't but is just done more labor-efficient now. 50 years ago there were still a ton of small farms, at least in the states where everyone actually lived that weren't flyover.
>>77321003>Might be interesting to see BJ try out the Yamanaka factors but we know he won't because this grifter doesn't try anything he can't sell.Wut, he's literally on turmeric and apigenin.
>>77321283>more labor-efficient nowIt's all just beaners, nogs and Quebecers in my area.
>>77321456You don't understand how inefficient they were in the past, there's a reason 10 hour workdays were the standard for farmers in the past>No standardized large crates, instead you had these funny wooded jenga boxes you had to stack in a certain way>Have to climb literally 20 feet up a ladder to pick apples (something unheard of now)>It wasn't as common to train things like brambles - now they're well-trained with varieties made to produce in the first year even on primocanes, thornless varieties now>Common farm equipment that's used like their little farm golf carts wasn't a thing back then, you had to wait for the tractor>The apples weren't moved with a modern forklift system, instead they had "risers" that were basically big shopping cart conveyor belts that carried them all the way up to the top of the cooler, manually loaded on and offI could go on and on but there have been a massive amount of labor savings just in terms of standardized equipment, equipment that isn't a just a tractor, better storage, ect.Of course picking the stuff is always gonna take a niggerton of labor. I'm sure the practices for many strawberry farms have improved to reduce this the same way apples have, more productive varieites with larger berries being a big one - with a larger berry you have to pick less to fill the same amount of containers, so berries twice as big will pick twice as fast.
>>77321456I thought the white candian frenchies somehow managed to become the ruling class there? Are they still common in the low end jobs?
>>77321471The ones who travel to BC to pick fruit are mostly degenerates
>>77321323>tumericAre there actually meaningful benefits? Don't you need to take like 5g of tumeric to get a decent dosage. It tastes like ass.
>>77318216Eww.
>>77318216This guy looks insanely healthy for 48. Sure, some of it's a little off but that's because he has a mix of aged and non-aged features.
>>77318216If he cares so much about living forever why doesn't he move to okinawa or switzerland? Surely breathing in the LA air cant be good for you
>>77321511mogges by 60 year old ChuandoTan
>>77318960https://youtu.be/9ZbrvKY94i4pyoapple is currently 36 and id still hit it
>>77318216Dear Original Poster, I have kindly rectified the errors in your graphic.
>>77321496Le tumor-ick is a bonafice Schizo Yarmulke drug. Picrel.Might get liver skill issues running doses up around 5g for too long though according to the tox lit; I personally run much lower doses with piperine for improved bioavailability and milk thistle plus NAC for hepatoprotection, also cycling off monthly unlike Bryan Johnson.
All the haters here who are jealous of the young unc.
>>77318216My gym has an Evo360 machine and it said my biological age was 1 year below my real age so he's not faking shit
>>77318216I don’t think you can reverse or stop aging but you can slow it down significantly
>>77321043>>77321058as long as you're in europe you can stay out in the sun all you wanti live in australia and i burn in 15 minutes of sun exposure, except in winter where it may take a few hours in the clear sky
>>77319324he has the biological markers of someone who was sedentary and ate a poor diet, drank alcohol and dig drugs for the first 39 years of his life and the suddenly became a vegan health nut at 40; which is exactly what he did/is.
>>77321920Post body
Why are you mad at him? You people have no awareness. You should see him as a hero, he thoroughly went through every method and incidentally became the perfect experiment. Now we all know not to waste our money and just stick to basic care like Tretanoin, sunscreen, healthy eating. Not stressing. That's it. I started experiencing the same realisation as he did and you can throw a LOT of money at this dilemma. I'm glad I discovered him
>>77322584n=1 (unreliable)
>>77322586Doesn’t mean it’s completely useless. Retard.If I had a penny every time I forgot to click “next” on the captcha… this is worse than CBT
>>77322615It is completely uselessIf i run every lifting program ever my output on them doesn't matter as proof to anything other than my personal experience
>>77321511he looks like a 60 year old ghoul with another man's face stapled over his own face
>>77322586No idea what you just said and don't even want to
>>77318216He looks like a fucking freak
>>77322584Because hes a liar you retard, he literally photoshops test results and blocks anyone who mentions it, his own head doctor of his "blueprint team" quit over his dishonesty. What part of "he's constantly lying" do you not understand? You can watch him for 5 seconds and see that he's insane, and thats on top of all the actual insane things hes done. Remember the shit about his olive oil being the best in the world? He just blended two low quality grocery store olive oils and lied all about it, people sent his shit to a lab and when they posted about it, he just blocked them. He's also constantly suing people
>>77322648>He just blended two low quality grocery store olive oils and lied all about itThat's just too outrageous to be true. I don't follow him but I get the impression he's an enthusiast about this stuff, I'm sure he's not the most honest person ever but I think he'd have the pride about making a decent product
>>77318350It's chemical peeling and makeup. He looks like a woman in an ad, because he's using the same retarded products and procedures as they do.
>>77318934Goddamn, gook women are ghoulish.
>>77322629You Humans are all freaks
>>77318960The reason asians have child like face well into adulthood is because Asians have tiny dicks and are pedophiles so through millennia of natural selection the women have all kept their child faces. compare an adult east Asian to a literal 8 year old and the faces are the same
I'm so tired of influencer slop.They lie about everything. How does anyone still fall for this shit? How on Earth do you get caught defending them as fundamental to your personality?He's been caught intentionally misleading people by taking criticism out of context and pretending it is endorsement. He's been caught lying about test results. He's been caught using leveraged NDAs to bully people. His entire smol bean experiment gimmick is worthless. He would rather lie about the effectiveness of what he's doing to fool you into buying into it than advancing anti-aging science. All these fucking podcast addicted faggots are the sameThe Internet has given cluster b personality disorder scum an unprecedented amount of wealth and attention.
>>77318937>He said himself that 90% of all of it depends on your genes.>>77321007>And he's wrong.Indeed, current research says aging is around *exactly equal parts* genetics and environment.>Rethinking longevity: Genes account for 50% of human lifespan variation, study suggests>https://medicalxpress.com/news/2026-01-rethinking-longevity-genes-account-human.htmlprotip: lots of other diseases and traits are similar, if somewhat less balanced in etiology.
>>77321511>>77318216Bro looks embalmed fucking weirdo. Waste of time and money
>>77322655If this would be true, there would be news articles about it.
>>77323041See>>77322966He's constantly suing and legally threatening people
>>77322972Post body
>>77321323My cum can mechanistically induce anti-aging effects. Wanna try tasting it?
As someone who worked in the field the big blackpill is 90% of visible aging is literally just gravity and the vast majority of the rest is sun damage and genetic skin elasticity. Unless you hang upside down your not reversing or stopping anything. Everyone looks roughly their own age no matter the perception. Anytime you see a look how young this 70 year old looks its just a good facelift
>>77323041Yep, it would be huge
>>77323184>My cum can mechanistically induce anti-aging effects. Wanna try tasting it?No thanks; I get enough spermidine from wheat germ supplements. And yes, that's the exact same anti-aging chemical, kek.
>>77323253Post body
>>77323138>He's constantly suing and legally threatening peopleI hate to ask dumb questions, but sauce plz.
>>77323253You mean the same spermidine that the ITP tried to get to work but it couldn't even get absorbed into the bloodstream so they had to abandon it?>inb4 muh fat solubilityThat's a common excuse for when something fails in the ITP but fact is, they got all fat-soluble chemicals like resveratrol absorbíng correctly in the trials so far (even if it had no lifespan effect). When something doesn't even get absorbed into the blood, it means it's fucking useless and people who still take it are retarded. As expected of a frogposter.
>>77323309You're talking to someone who doesnt lift, doesn't take anything and just spends their days spamming chatgpt quotes here.
>>77323322I am aware of who this schizo is. Don't forget he has admitted to balding too and doesn't even take any of the big 3.
>>77323309Breh, molecule skill issues:>https://www.sciencedirect.com/science/article/pii/S2772753X25000371>Novel protocol significantly improving spermidine content in extracts from wheat germ: Aqueous conversion of polyamines into neutral-base form, solubility in ethanol and acid precipitation as phosphate saltsThis is just like with fisetin where it didn't do jack shit, yet I know to use carrier solvent with a COMTI.
>>77323326Dr Miller - has a PhDYou - balding schizo spamming on /fit/Spermidine - dead end, doesn't get absorbed into the bloodstreamYour mechanisms are retarded. You are retarded. Kill yourself.
>>77323329Nope.>Supplementation of spermidine at 40 mg/day has minimal effects on circulating polyamines: An exploratory double-blind randomized controlled trial in older men>https://www.sciencedirect.com/science/article/abs/pii/S027153172400126XBunch of PhDs are still researching it. NIH's PhDs working with fisetin couldn't even figure out something as simple as ethanol, and have been BTFO even by other mouse trials not using it.
>>77323341Fisetin did get absorbed into the bloodstream in the ITP, it just didn't have any lifespan extending effect. The ITP supersedes all other animal and even small human research. If something doesn't work there it means the other labs either outright faked their results, had a bad methology or used special mice breds.Keep posting my responses into GPT all you want but you won't live even a single day longer no matter how many thousends of dollars you waste on useless supplements.
>>77323326>>77323341Post body
>>77323345>Fisetin did get absorbed into the bloodstream in the ITPThey said it "failed to significantly lower markers of senescent cells (p16Ink4a mRNA) in the liver, kidney, or brain."Yet, pilot trials on humans are saying shit works:>https://rupress.org/jhi/article/2/CIS2026/eCIS2026abstract.223/282062>Novel Senolytic Clinical Trial in CVID with GLILD>https://www.mdpi.com/2072-6643/18/3/433>The Effects of Interval Resistance—Aerobic Training and Fisetin Supplementation on Asprosin and Selected Adipokines in Obese Men: A Double-Blind Randomized Control TrialSo yeah, we're back to NIH having molecule skill issues. Shrimple AAS.
>>77323372Again, the ITP supersedes anything except for clinical trials. Moreover, this clinical trial didn't even look at a lifespan extending effect but some other parameters (in special populations such as obese men) where they hoped to achieve statistically relevant (but not clinically relevant) improvements. You are grasping at straws here. Any study will do in your confirmation bias and any stronger study will be disregarded.
>>77323388this trial*
>>77323372Post body
>>77323388Try explaining all these findings without admitting to NIH's molecule skill issues:>Fisetin reduces the senescent tubular epithelial cell burden and also inhibits proliferative fibroblasts in murine lupus nephritis>https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2022.960601/full>Fisetin-Mediated Topical Modulation of Senescent Cells in Skin Improves Wound Healing Dynamics in Diabetic Mice>https://journals.sagepub.com/doi/abs/10.1177/21621918261426580>Intermittent supplementation with fisetin improves arterial function in old mice by decreasing cellular senescence>https://onlinelibrary.wiley.com/doi/full/10.1111/acel.14060>The Senolytic Drug Fisetin Attenuates Bone Degeneration in the Zmpste24−/− Progeria Mouse Model>https://onlinelibrary.wiley.com/doi/full/10.1155/2023/5572754
>>77323418Post body
>>77323418Again, low quality studies don't supersede high quality studies no matter how many of them you spam. And none look at lifespan effect.
What are his cortisol readings? He is pushing his body extremely hard
>>77323442>exercising for an hour a day and eating a healthy diet would spike an americans cortisol
>>77323432Nice try NIH, but I already regrew hair off of this shit through both topical and oral RoAs with carriers and metabolic-modulating adjuvants, so I'm still gonna call molecule skill issues and spam a few extra studies...>Fisetin is a senotherapeutic that extends health and lifespan>https://pubmed.ncbi.nlm.nih.gov/30279143/>Fisetin Attenuates Cellular Senescence Accumulation During Culture Expansion of Human Adipose-Derived Stem Cells >https://academic.oup.com/stmcls/article/41/7/698/7190776>Fisetin and Lifespan: Key Findings from Animal Studies>https://masi.eu/en-sek/blogs/longevity-news/fisetin-and-lifespan-key-findings-from-animal-studies>Exploring the anti-aging effects of fisetin in telomerase-deficient progeria mouse model>https://peerj.com/articles/16463/
>>77323981Post body
