previous: >>43677083QOTT: Have you tried pioglitazone, nona? Why or why not?• Help, advice, guidance on meds and dosages• HRT related medical experiences and research• Availability and pricing of medications• Rational and scientific discussion▶ FAQ: https://pghrt.diy/▶ Info Directory: https://diyhrt.info/▶ MTF Vendor index: https://diyhrt.market/▶ Articles/literature: https://transfemscience.org/▶ Estradiol simulator: https://estrannai.se/▶ TransDIY: https://www.reddit.com/r/transDIY▷ Pill ID: https://www.drugs.com/imprints.php▷ DrugBank Database (requires account): https://www.drugbank.com/▷ Basic MTF HRT: https://apps.carleton.edu/campus/gsc/assets/hormones_MTF.pdf▷ MTF HRT ranges: https://www.hemingways.org/GIDinfo/hrt_ref.htm▷ Powers Method (2020): https://powersfamilymedicine.com/s/Healthcare-of-the-Transgender-Patient-V60.pptx - Anything from Powers should be taken with a grain of salt.▷ Endocrine Society Guidelines: https://academic.oup.com/jcem/article/102/11/3869/4157558▷ Transline Guidelines w/bicalutamide (2019): https://transline.zendesk.com/hc/en-us/article_attachments/360047702053/TransLine_HRT_Guidelines_FINAL.pdf▷ WPATH Standards of Care: https://www.wpath.org/publications/soc» Blood tests by mail: https://www.letsgetchecked.com/ - DIY finger-prick samples. Expensive.» Blood tests (US): https://www.privatemdlabs.com/, https://www.labsmd.com/» Blood tests (UK, Ireland): https://www.medichecks.com/» Blood tests (Canada): https://bloodtestscanada.com/» Blood tests (Sweden): https://werlabs.se/» Lab Services Handbook: https://www.healthcare.uiowa.edu/path_handbook/Links that need updating:∗ Survey data: https://1drv.ms/x/s!AudRJceTA5C9cyIWo6_X14AvHyM∗ HRTGen Data Analysis (2017): https://1drv.ms/f/s!AudRJceTA5C9gRLLWnbpdzlIxe4r∗ HRT Info Sheets: https://1drv.ms/f/s!AudRJceTA5C9gQnyM7wxZcBGWRzW
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>>43710694Where to get pio in burgerland??
>>43710712dashpct ships it
>>43710735aipctshop is like 1/7th of the price.indiamart also has some good sellers.
How are you supposed to take domp and how much?
yay new hrtgen>>43712309https://www.canadianbreastfeedingfoundation.org/induced/regular_protocol.shtml
I’m starting hrt this week and was wondering on the best place to purchase needs/alcohol pads from
>>43714774needles*
>>43714774online pharmacy. get fixed needle insulin syringes
Does anyone have experience with folx health? Do you know if they'd prescribe prog immediately without having to wait a year, for the benefits of it while minimizing breast growth
i am never ever buying from the us as an europoor. such terrible fucking experience omg
>>43715523again*
>>43715523pardon?
>>43715510at any informed consent practice you can tell them you've been diying the medication you want at x dose and they'll just give it to you at that dose if it's a medication they prescribe, there's no way for them to know if you're lying.but if you're just starting you actually should skip the prog for now imoif I understand what it does correctly it's not something that'll just give you bigger boobs, it helps trigger the last stage of breast development where your milk ducts grow, but that actually prevents any further growth and if it's way too early you would miss out on most of the growth you could've had without the prog.
i dont know if its pio or prog or whatever but this past month it feels like most of the weight i gain just goes to my breasts im a big fan of it
>>43715510Yes and they fucking suck. Horribly expensive and they stopped providing a lot of their services. Can't even get Bicalutamide with them anymore.
>>43710694Im buying Pio for the first time today. Mostly due to money reasons I lost 7kg last year and my BMI is almost 18, I was waiting to get a flat tummy bf starting, but I'm too close to underweight so just may as well bf I lose all my thighs and my face gets dry.I heard starting dose is 15mg, I thought I could spend a week or two on 15mg before changing to 30.Anyone to tell me their experience with Pio? Is there anything I should know or expect ?
>>43710694
Threadly reminder that this is the information 'medical professionals' are working off when they prescribe dosages. They have no idea, they are just looking at this pamphlet.-Bloods at peak not trough-Targets 100-200 E, <55 T-Spiro up to 400mg/day-Finasteride as an AA-Progesterone from day 1Dosages: 2mg swallowed pills, OR 0.1mg patch 2x/week OR 10mg valerate/week.Don't let this happen to you.
am i retarded or is there not a pio dosage guide in the OP? someone spoonfeed me, i'd really like to accelerate some of these fat deposit changes.
>>43710694I tried buying pio from india but it got impounded by customs :<
Meeting with my Endo soon and was wondering when I should start prog? I'm 6 months into hrt but I heard some people say it's better to wait until you're a year in???
>>43718648>am i retarded or is there not a pio dosage guide in the OP?There are dosages for Pioglitazone provided @ https://trans.diy/feminizing/pioglitazoneYou can choose to dose between 15 mg per day to 30 mg per day.
>>43718396>Targets 100-200 E, <55 TThis is somewhat debatable because that is what most people expect from monotherapy unless you need a slightly higher dose to suppress testosterone from your testicles.A cisgender woman has testesterone levels of between 6 ng/dL to 86 ng/dL and monotherapy will reduce your testosterone levels down to less than 75 ng/dL or so.>Progesterone from day 1To be honest, there has not been too much evidence that starting progesterone early messes up with breast development. In some countries, there are private clinics who prescribe progesterone on day 1 and trans women end up getting C or D cups fine. Tubular and tuberous breasts are genetic. Everyone's breasts comes in different shapes and sizes.If you go through some of the pages in https://www.007b.com - there are multiple cis women who had AAA cups before pregnancy and ended up having D/E cups during/after pregnancy so the information we have around high E and starting prog early stunting feminization is poor.Trans women could achieve similar results by making your own vials of E2 and P4 and then injecting them into your body to mimic 1st, 2nd, and 3rd trimester.
>>43718900-Blood tests not at trough-Finasteride as an AA-Spiro up to 200mg 2x/dayAlso Prog from day 1 adds an unnecessary risk of breast bud fusion for no benefit
Can i take hrt as a straight cisgender male for looksmaxxing reasons.I'd like to be cute and also not lose the functionality nor the size of my dih
I just bought this cos a redditor said it will shrink my cock if I use it as lube to jerk offI want to sissymaxx I'm taking a 2mg ev sublingual everry 4 hours and 300mg spiro daily will this prog cream really work?no I can't inject or get patches, this is it.
>>43719631no it will give you tits and make you retarded
I'm starting prog, I see 200mg recommended but I only have the 100mg micronized capsules. Is there any downside to just taking 2 of them?
>>43720457>Is there any downside to just taking 2 of them?No. Also, take it rectally because it has higher bioavailability instead of the progesterone being destroyed by your liver and being converted to useless metabolites.
>>43710694What are all the options for increasing libido on HRT?So far I have:- changing HRT dose- progesterone- supplementing low dose androgens (e.g. T, nandrolone)- PT-141
>>43720516Have you tried viagra? Perhaps applying Testogel on your genitals?
Any nonas ordered from symphony UK to EU mainland?My package is behaving weird, symphony says theyve shipped it, "royal mail" says they're "waiting to receive it". Idk what that means
>>43717083Thank you anon. I don't actually want any further breast growth. I'd like to take prog with estrogen for mood and mental health. My only concern as far as breath goes with prog is that it could possibly mishape what my breasts are like at the moment.>>43717102How bad is it? I only need estrogen and prog, no antiandrogens. I was thinking of going with them for a few months then leaving and doing it on my own and DIY'ing after things stabilize. For several reasons I don't want this showing up on my insurance which is why I'm looking for a kind of doctor-DIY hybrid strategy
>>43720586The penis works fine, it’s a libido issue.
>>43718871>15 mg per day to 30 mg per day.45mg is technically safe but unnecessary. 30mg is probably the best dose; it's the most well-tested amongst resident honscientists. >>43719923It won't. Go play with your sissy nipples alone in your room you fucking faggot.>>43720249Looksmaxers are already retarded.
>>43721470>Looksmaxers are already retarded.what makes you say that?
>>43721563their ringleader smokes meth to lose weight. he might as well just do 2,4-DNP at that point.
should I throw away the Indian GnRH (Lupride Depot) I bought? It has a very thick needle and I don't have issues with cypro.I've read the side effects of GnRH and it looks scary, also the solution looks milky after mixing the powder, I don't really want to die a painful death
>>43721600>I've read the side effects of GnRH and it looks scarymost of those are side effects when you aren't supplementing hormones. GnRHs essentially shut down excretion of GnRH, breaking the LH/FSH secretion that tells the gonads to go make T. when you don't replace it with anything, you essentially get hormone deprivation symptom. those are not an issue when you're supplementing hormones.in actuality, GnRHs are actually the lowest side effect method of suppressing endogenous hormones. monotherapy is way cheaper though. any reason why you don't just do that?
>>43721627how do I do monotherapy?
>>43721695generally injecting 4mg EEn or EC every 7 days.
>>43721714I'll stop using cypro then and see if anything changes. I'm using 5mg currently
>>43721600what gauge needle is it? I never used one.I am on Medroxyprogesterone Acetate and it has a 22 gauge needle which is thicker than the needle I use for estrogen injections (31G).btw zoladex gnrh needle is 16G and hurts like hell. that is the injection given to cis women and trans men who have endometrosis and uterine fibroids and breast cancer.
>>43721600that's how it is for aqueous solutionsmedroxyprogestone is milky too
>>4372249020G lol and it was long, I'm not poking that in meI use 32G for Een draw + inject, the 20G gauge one looked thick in comparisonI currently have the solution mixed so I guess I'll have to let it waste away, there goes my money wasted
I NEED FUCKING HELP PLEASE FUCKSO I HAVE A 40MG /10ML ENANTHANATE VIAL AND I HAVE SYRINGES THAT GO UP TO 1ML, SO THEIR LIKE 0.1 ALL THE WAY TO 1.0ML, AND I DONT FUCKING KNOW WHERE ON THE SYRINGE IS A GOOD FUCKING DOSAGE THAT WILL ACTUALLY MAKE A FUCKING DIFFERENCE, I NEED FUCKING HELP :(
>>43723344draw like 0.15ml
>>43723367I LOVE U YOU DONT EVEN FUCKING KNOW I MEAN IT please may God bless you!Id injected 0.5 on the syringe and ive felt so hopeless and terrible and was worried i was gonna die , the syringe and needle is pictured. ive been on EV for the last 7 months and got on EE
How good is transdermal progesterone? Worth doing instead of boofing?
>>43723344don't listen to the other retard, draw 0.1ml (4mg).
>>43723622ive been following a guide that suggests 0.15ml but i can try 0.1 i guess seems small though. so also though, i drew this much to the 0.5ml line, how long should i honestly wait for the half life to just process through until i take my next shot. 0.5ml had to have been WAY too high before EE my EV dose always hut the 0.25ml line on syringes. so i really think i fucked my calculations up and thats why i took 0.5ml
>>43723676nigga that's 20 fucking mg, you're toast. seriously though how could you be this careless? i'm not a doctor but i think you should at least skip your next injection to wait for your levels to drop down but you will probably feel like shit for a bit.
>>43723750yeah i was thinking to do that desu but ouckily i gave a rather clean diet so ill not vape or anything and ill chill out until the next shot which would put it out at June 6th.i just havent had anyone at all show me how to do this ...Nobody. and I also overdosed accidentally once with my EV and my levels were 1,321 but that was months ago.......i wont die right?
>>43723837no of course not but the spike and crash in your levels will be unpleasant.
>>43723861oh -well thnak u for being homest because if you hugboxed me i wouldve felt worse so thank u i mean it and that wxplains why ive been screaming, crying, depressed and laughing st the stupidest shit the last 4 days
>>43710694Any mad science for post 5yr breast growth?Don't care for danger or theoretical level, willing to risk most beside masculinization
>>43724043drink the prog
>>43724043corticosteroids or topical e2+p4 or acetyl hexapeptide 38 or just eating more on pio
why would someone take Dutasteride instead of Finasteride or Bicalutamide
>>43725227bica blocks all androgenic activity (dose dependent though), duta and fina is very similar except duta hits more t -> dht enzymes iirc, but for most things that matter they are equivalent. if you u want to be twinkish but still be on a androgenic profile, fina and duta are good. if you want to have a eunuch profile go for bica (just take liver function tests every 6 months), and an estrogenic profile w bica + e2
>>43721470What do you mean it won'tit's progesterone
I've been on hrt for 7 years with very little breast development as a result of regular starvation. I've gained some weight and my boobs got a little bigger, but I'm worried if I'm cooked
>>43725855prog or clobetasolmaxx imo
has anyone else developed a needle phobia because of injections? before i could do it no problem but now i just can't. the moment the needle touches my skin it hurts and i get scared even though i used to not even feel them. i'm not injecting today it's too hard.
>>43720472Awesome, thank you!I know people usually take the entire dose before bed because of the drowsiness, but I wonder if taking 100mg in the morning and 100mg at night will have better levels. Prog has a half life of 12 hours apparently
>>43726316If using MCT Oil, use very thin needles (31G or 32G) on your abdomen using SubQ administration.If you are using those then just use numbing cream on your injection site, wait several minutes, and then clean the injection site with alcohol wipes, and then inject.
>>43725605bump come on it's got 20% prog per pumpit must be of some fucking use to me