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>>43734648
When the OP says >inb4

>>43734648
>300-500 range during her cycle
Measured consistently around ovulation? Or is she saying her levels never drop below that?
Some people need high levels to achieve suppression but it's not everyone. Studies confirm this.

>>43734780
>Or is she saying her levels never drop below that?
this i guess lol

>>43734797
Maybe in pmol/L otherwise I'm not a doctor but I feel like a medical thingy is going on

>>43734648
it went to shit since two years ago. there are obvious posts from children that are left unmoderated. the mods are selective on concerns brought up about homebrewers and often delete the posts. the megathread has not been updated in over a year. you're going to see its downfall soon enough as a consequence of the social media bans coming into effect in the coming months, which will require you to submit your id to access nsfw subreddits

>>43734863
doubt because she used the 100-200 reference in pg/ml. she is probably just lying

>>43734867
Digital id all about data and stopping lgbt information

>>43734867
what is surprising is just how much honscience is there now. HRT subs used to actually be good a few years ago

>>43734903
Just blast estrogen sis.

Unironically this will get you further than modern hrt discourse

>>43734925
true tbhon

>>43734903
>>43734867
So fucking annoying the OG /lgbt/ gens never codified /hrtgen/'s accumulated knowledge into a cohesive DIY HRT bible to pass down info in a streamlined vetted manner to the next generations

>>43735197
>cohesive DIY HRT bible
there are many of those. hons just dont use it

>>43735239
show

>>43735239
show

has anyone ever seen a passoid on monotherapy high estrogen honscience? i have met 2 passoids irl and both were on patches + AAs prescribed by a real doctor.

>>43735348
im talking about TFS/some of the tranny wiki, DIY HRT directory, whsah.co, theriaca.co, trans.diy, etc
and homebrewers guides from lena, spiffy, for transdermals and from some new sellers

>>43735454
>i have met 2 passoids irl and both were on patches + AAs prescribed by a real doctor
youngshits?

>>43735484
both started at 18 not sure where you place the cursor for youngshit

>>43735197
>>43735239
hons wrote the bible and convinced themselves they weren't hons
>>43735454
all passoids I have seen were on pills or patches and highest saw was 6mg pills
>>43735484
I need to start seeing some injection monotherapy passpoids that aren't just youngshits

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>>43735197
There is, but a lot of what we knew over a decade ago is out of date information by now or has not been maintained by the next generation. Hell, that spreadsheet on hrtgen still has my entry from 10 years ago, and hardly anyone has filled it.

>>43734648
Parents n leo

>>43734648
Sorry Im a retard but are you saying that 300-500 being an acceptable range for mtfs is incorrect or just that a cis woman claiming that she naturally stays within that range is wrong?

>>43735828
>a cis woman claiming that she naturally stays within that range is wrong?
this and almost everything else

>>43735828
NTA but 300-500 is very much incorrect for anyone.

>>43735929
500 is a good limit for mono

>>43734648
My levels are around 150 and my T is more than suppressed on mono therapy; <20. 5mg/week ecyp.
I realize that's anecdotal, I'm sharing to point out it's possible without an AA not that this is the rule

>>43735931
works cited:

>>43735929
I thought higher levels weren't really a problem as long as shbg wasnt above 125ish?

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>>43735966
https://en.wikipedia.org/wiki/Pharmacodynamics_of_estradiol#Antigonadotropic_effects

>>43734867
> the mods are selective on concerns brought up about homebrewers and often delete the posts
do you have evidence of this? I’ve occasionally heard this before and have a hunch that certain european homebrewers are friendly with the mods

>>43735470
don't bother recommending trans.diy. it is ran by a just turned 16 year old (xitter: emdo crine moder). when you're submitting so‑called "scientific papers" and an AI‑made website, you shouldn't be taken seriously. let alone if you're 16 years old doing this
>>43736639
i'm not going to nitpick posts that have been deleted. i don't waste my time taking screenshots or keeping logs. i'd be catering to the five people who actually give a fuck
>archived.moe/lgbt/thread/43608388

>>43737121
i do think you used nitpick wrong here?

>>43735197
The info on/out there is already good, better than its ever been - people are just so retarded nowadays, they can't think for themselves, make use of the resources and info provided without excessive hand holding, do research themselves, and engage with peers sincerely beyond sealioning second hand honscience/anecdotes or catty cliquey drama. The amount of learned helplessness in today's generation of trannies is insane. What exactly do you people want? You act like golems who need explicit instructions on how to conduct yourself.

>>43737256
ironic huh

>>43737256
>>43737269
ty for pointing that out. i'm not sure why i used that. i meant to say "archive", given the context

>>43737268
very true

and you know none of these retards are getting blood tests done after refreshing transdiy every day and buying their vials one at a time

>>43735197
/hrtgen/ has had good info for years now.
MtF HRT isn't rocket science. Make sure your E2 is in the 100~200 pg/mL range, and that your T is blocked (< 40 in blood tests). That's it.
anyone can reliably do DIY HRT if they have access to blood tests.

do oldfags still recommend the powers method or did that meme finally die out

>>43735454
I'm on sane dose monotherapy (4mg/week valerate, 258pg/mL at mid-cycle, no idea at trough but probably within endocrine society guidelines). My T was 7 so why would I take an AA?
Are people just going for the high score or do they really need like 500pg/mL just to keep testosterone down?

>>43737121
i did think her sites all felt vibecoded but i gave her the benefit of the doubt... yikes

>>43737475
nta
people are just going for high E, but some do need higher E, especially at the start
my T was fully suppressed with 100 pg/ml after 2 years on HRT

>>43737465
funnily enough, powers stuff completely disappeared for a while after the whole TFS thing, but trannies are starting to talk about him again, a lot. dark times

>>43737465
>>43737537
when i revamped hrtgen i added a note on powers being cucked, at least
t. newfag

>>43737514
I had it probably unusually easy in that regard. Started on sublingual + 50mg spiro.

2mg: ~360ng/dL
4mg: ~90ng/dL
6mg: 15ng/dL

For that last one my E only came back 89pg/mL. I dropped the AA around a year in and have been monotherapy since (though on 8mg/dL sublingual followed by my current injection dose).

But I thought unique responses to this stuff were why we titrated doses instead of just blindly estrogenmaxxing.

>>43737564
>But I thought unique responses to this stuff were why we titrated doses instead of just blindly estrogenmaxxing.
you can do it both ways

>>43737557
thanks newfren

>>43737667
FWIW there is limited study into this and you are correct—there doesn't seem to be any significant value in micromanaging levels. Though I doubt there have been 40 year follow-up studies on total mortality on 200pg/mL vs. 500pg/mL and a lot of you might actually be on estrogen for that long (or longer) so if it were me I'd still be slightly careful.
The flip side is there's no real evidence that 500pg/mL causes faster/better feminization than 200pg/mL either.

>>43737537
I'm out of the loop. What was the TFS thing?

>>43738017
transfemscience (mostly aly) used to fact check powers claims/theories here and there for years. eventually powers dropped a full presentation and aly wrote a dedicated article fact checking all of the honscience. after a while, powers sent an email threatening to sue TFS explaining how he was going to spend all the money needed to shut them up. TFS made everything public, deleted the article and anonymized all the criticism related to powers in other articles

>>43738268
is that threatening email from Dr. Powers available anywhere?
What a weird reaction.

>>43738752
google it and you will find tons of archives

My levels are always 250-500 no matter how much i inject my docs keep trying to adjust to a hon dose but my body refuses. I was doing monotherapy but went back to Spiro briefly after missing a dose of E and feeling weird

>>43738833
interesting... I always feel weird, have never felt normal a day in my life

>>43738268
I will never forgive powershons for flaming Aly. She was right and all the good info we have now is mostly thanks to her compiling it from scientific journals im too lazy to read

>>43739223
powers was extremely sus from the get-go
>hurrdurr my cat is very long now let me measure your penis with these calipers, smoke some meth and 'meditate' on the results until I can post my theories on my own personal cult literal subr*ddit
uhh-huh carry on but at a distance

>>43739257
But is ur urethra slightly off center? It must be a sign!

>>43739380
yeah I'm not gonna inspect my urethra I can barely stand looking at my penis anyways don't care if I'm a urethrahon that's the least of my worries

>>43734648
Medfag here. None of this is medical advice. Talk to a fucking doctor.
The correct answer to "how much/what hormones should I be taking?" is that there is no correct answer. Every person's body is different and something like this cannot easily be boiled down to "keep your levels above x value". Epigenetics, an emerging field of medical research, shows us that genetics and gene expression are fundamental to pretty much every aspect of your body and personality, even down to things like conscientiousness and what foods you like. It's not just genetics, but your environment can also alter what genes get expressed or suppressed. There's millions or even billions of variables at play.
We know things like "if you take aspirin your back will hurt less" and "eating a bunch of sugar is bad for you" but a lot of medical science has to be holistic by necessity so there will never be one correct answer to how your transition should pan out. Some people are more or less receptive to certain hormones. Some people have fucked their liver up with alcohol because they're a depressed troon and this will affect how your body processes the various things you are injecting, swallowing, etc. Some people have naturally high testosterone that is resilient to being suppressed. Some people smoke. Some people have a poor diet. Some people life weights. Some people have lower body fat (metabolically active adipose tissue is necessary for proper processing/storage of estrogen, anorexic trannies are mostly pissing out the hormones they take) There is no magical formula that works for 100% of people.
This is why you should be working with a doctor and not just taking medical advice from fucking Reddit.

or you can just remove your testicles and inject large amounts of long lasting estrogen ether. just whatever people say is the maximum dose + some extra. there's zero downside to taking more, cis women when they're pregnant are exposed to like uber omega levels. you don't need to pay doctors or do blood tests or anything really. of course you should be generally healthy overall for your body to respond well

Just because it isn't clear anywhere, when people talk about an optimal range, eg. 100-200 pg/ml, are they talking about trough level being somewhere within that range, average levels being within that range, or are those meant to be the peak and trough throughout a whole cycle?

Also, for anyone claiming that 100-200 is an acceptable range, may I ask what your reasoning for that is? I'm not disagreeing that feminization can happen at low levels but I'm wondering if your only reasoning for avoiding going higher is just the increased risk of raising SHBG or some other health effect I'm unaware of

>>43739567
>The correct answer to "how much/what hormones should I be taking?" is that there is no correct answer.
OK you're not wrong and definitely get a real doctor and not one that studied at the Reddit Institute of Honscience.
But also is there an actual established protocol to account for these variables? Like if I go to a random endocrinologist and I get on stable levels where my T is suppressed and they aren't concerned I'm at undue risk of death by blood clot, but I don't seem to be responding well for some reason, do they actually have a plan of attack? Something actually supported by evidence?
My current doctor pretty much only cares that your T is suppressed. The quality of care we get is on average pretty terrible.

My not-a-doctor general life advice is to quit smoking and ideally quit drinking and generally try to be otherwise healthy, in large part because the medical system doesn't really no what to do with you but it will probably blame your hormones regardless. And even if they don't governments will, because their sole goal is to ban trannies.

>>43740550
Most doctors seem to want to measure mid-cycle, which they assume represents an average level.
They're probably wrong, and the actual curve depends at least somewhat on where you inject (esp. IM vs. subq) and definitely depends on the ester and probably also the individual human.
Like I want to see the math demonstrating that for an averaged EV pharmacokinetic curve that injection+3.5 days corresponds to average daily level across the week.
But if you're measuring at trough you're underestimating exposure by a lot, especially on EV.

>>43739767
Do not do this.
>>43740655
Something you have to understand is that our modern day interpretation of "transgender" is something entirely new. Historically speaking there were transsexuals and SRS was standard. There was no nebulous concepts like "gender euphoria". There were also a very narrow selection of doctors that could actually enact a sex transition protocol.
Nowadays we expect every single part of the medical industry to know about "trans health" and that's just not feasible. Your family doctor is not equipped to handle the full scope of gender transition, especially when guidelines and expectations are constantly changing. Also keep in mind the medical industry AS A WHOLE has not recovered from COVID. It was already strained and understaffed before then, now it's even more so. Your doctor probably has an unreasonable case load. No one is trying to kill you.
My recommendation is to ask for a referral to a specialist if you are unresponsive to hormones. Do not cut your own balls off.

>>43740698
>No one is trying to kill you.
I know that. My point is to my knowledge there is not much evidence based medicine for this. That is most definitely not *my* doctor's fault.
Especially on optimizing cosmetic outcomes there's close to zero study, Wasn't it this year we finally got an attempt to study whether progesterone improved breast development? Everyone's just taking it on vibes.

Thankfully my own response to hormones has been if anything usually good. I haven't needed heroic doses, and my testosterone collapsed quickly and easily: >>43737564
I basically have a model endocrine system in that it was mediocre at best at masculinizing me but immediately got the fuck out of the way and let estrogen work.
You could say a specialist titrated my current injection dose, but she started me on 4mg/week and was satisfied with my follow-up labs on that. So her conclusion was to keep cruising on default settings for now.

>>43734925
What even is modern hrt discourse? I've always just pieced together info from /hrt/gen, transfemscience, and will powers

>>43740672
If I'm underestimating at trough I'm probably well on my way of getting breast cancer then. My tough levels hover around 450-500 for whatever reason even though I'm on a fairly reasonable dose (5mg/5days). I'd like to lower it but last time I did my T started shooting back up.

Again I ask, is there any evidence for risks other than clots/cancer associated with high levels? As far as I'm aware high levels shouldn't really affect transition results as long as SHBG doesn't wander much above 125

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>>43734648
Anyone else get the feeling that DIY just isn't as common anymore? I think young people all know about trans stuff and aren't tech literate or rebellious enough for crypto, so they just go the official route when possible. They're probably on blockers or sitting on a waitlist. Passoids being more common might just be from the earlier transition age instead of anything to do with better methods being developed. This is just a guess though since I don't really go to babytrans spaces. But most DIY resources seem to be from 5+ years ago.

>>43734780
>Some people need high levels to achieve suppression but it's not everyone.
yup
i can suppress my t with my trough levels in the high 100s/low 200s

>>43740944
My own endocrinologist told me typical is 3-5mg (EV) per week, but obviously based on the individual's labs.
There's one paper floating out somewhere that concluded there's no real evidence in support of micromanaging levels. HOWEVER if you're transitioning in your youth and you intend to stay transitioned until old age you're gonna be on estrogen for a long, long time, and follow-up studies on high-dose estrogen therapy like that going out decades don't exist as far as I know. We're kind of on our own. I'd be careful if it were me.
One thing I think another anon was alluding to is it's a fairly modern phenomenon to transition and keep your testes long-term. Back in MY day (I am in fact old) you got SRS, which ought to make your T easier to suppress.
Though also back in my day they gave you Premarin. Or worse, ethynlestradiol (the stuff in oral contraceptives).
Also also back in my day a lot of girls died of blood clots.

Are you working with a doctor? Do you have the option to work with a doctor? I'll trash the medical field all day but taking medical advice from 4chan might actually be worse than taking it from Reddit.

>SHBG
I don't think most endos even test SHBG, and the idea that it starts causing absolute free estrogen to drop is absurd. Free E2% drops of course
I have heard some people have a harder time than others keeping T down :(

>>43740982
Access to hormones on an informed consent basis at least where I live expanded dramatically. People DIY for lack of better options for the most part I think, and not as a giant middle finger to the medical system.
Like why buy hairy bathtub estrogen when you can get something made to USP standards?

>>43734780
her cycle is the peak/ trough cycle after injection newfag

>>43741080
(1/2)
I'd like to get SRS or at least an orchi eventually and I hope I will have an easier time with meds and labs then. I'm relatively young (mid 20s) so I'm not driving myself crazy worrying about a blot clot yet but that may just be the confidence of youth. These surgeries are probably still at least a few years away however so in the meantime I guess I'm more concerned about the potential acute negative effects high estrogen could have towards the rest of my transition by stalling growth and such. I know I keep harping on that but I'm just really unsure if it's something that actually happens or it's just fearmongering. If you or anyone has anything to point my towards in this regard I would really appreciate it.

I do have a doctor but for better or worse he kinda just sits back and lets me dictate what I want to do. I don't really trust his judgement on things because he didn't seem to understand why I was concerned about my DHT and the initial dose he started me on was WAY too high (10mg/7days). I've had to learn to give him some push back on stuff but it just sucks because at the end of the day I'm not a medical professional. I'm basically just trying to do my best to find whatever scholarly resources I can to inform myself on things since it doesn't seem like anyone else can. FWIW I don't blindly trust anything I see on here or reddit or wherever. I ask around in a lot of places and try to pick through what I can and see if I can actually confirm any claims with actual research/medical papers. This is extremely annoying to do because nearly everyone gives completely different advice and there has been hardly any hard science done to back anything up. Often times I'm just frustrated to the point of tears because I feel as though my whole transition is riding on the anecdotal medical advice of others.

>>43740982
I think hrt just isnt as popular anymore

>>43741080
>>43741674
(2/2)
I've pushed to get a lot of things added to my lab orders because I like having as many data points as possible to aid in my decision making. My SHBG was 127 nmol/L at last measurement which is towards the high end of the scale or just off it but I guess something that I don't think I have too much reason to worry about yet. (Again, please someone let me know if I'm wrong though!) I agree with you about the free E thing. Mine was around 1% which a lot of people told me was low but my absolute was above 4 pg/ml so I'm not sure why it would matter? 2% of 200 pg/ml is obviously the same as 1% of 400. Yeah never made sense to me to be measuring something like that as a percent.

I do seem to be having a hard time with T suppression for whatever reason. Even at my high trough levels my T still sits in the mid 30s ng/dl and DHT is at 11 which seems way too high as well. Can't seem to get LH to suppress either :( I may just be some genetic freak I guess. Makes me worry that SRS/orchi may not even be the solution as I may be producing all this adrenally. If I can't figure it out eventually I will have to reconsider monotherapy.

Despite all my worries my transition (17 months HRT) seems to be going okay but I might just be a bit overconfident. I've had breast growth and positive effects on hair and skin. I also think I've experienced a moderate amount of fat redistribution but that may just be regular weight gain. I was hoping for body hair to slow down a little and maybe some hip growth (I know that's pretty unlikely at my age) but oh well. That is to say, all this ranting and might just be worries about problems that don't really exist.

Thank you for your concern towards my health and everything, I truly appreciate it.

Sorry for the blogpost everyone

>>43739567
>Medfag here. None of this is medical advice. Talk to a fucking doctor.
>This is why you should be working with a doctor and not just taking medical advice from fucking Reddit.
why would i care about doctors opinions on things?

>>43741392
read again
>>43741675
lol

>>43739567
Ew go away

>>43741674
>10mg/7days
Damn and I feel like my peaks are a little intense on 4mg/7 days.

Yeah this is what I wish more doctors would see. We're doing our own research(TM) because we don't really have a choice. It shouldn't be that way but it is.

>>43741687
If LH won't go down either it may be gonadal testosterone so at least there's that. Though I think usually high dose estrogen both poisons testosterone production in the testes *and* suppresses LH.
Maybe powers isn't completely insane and some people's estrogen receptors are just cooked from birth. (Technically complete EIS is a thing but it's *rare*, from memory on the order of 1 in 400,000 people.) SHBG is another (imperfect) proxy for estrogen exposure as you said. Imperfect because it's affected by all sorts of things like insulin and alcohol exposure.
(Did you know drinking can increase SHBG?)

Anyway sorry you're struggling with it and I hope you get it figured out. I'm not honestly sure at what point estrogen levels become actually concerning.

also if you don't have sperm and are growing boobs, do you really need any more indicators that HRT is working?

>>43741733
>>43741944
The medical system is far from perfect but your doctor probably wants you to live.
>t. the anon whose doctors ran male reference range labs, warned her she might be anemic, then suggested it could be brought on by periods

>>43741974
i dont have a doctor, that sounds really funny. but discussing research is outside of their expertise anyway
in my experience, doctors dont really care if you live or not

I can't believe this thread is still up, I'm so happy I can say this:
>>43739567
Shut the fuck up faggot, fucking retard >muh doctor sheltered amerimedfag. Privileged sheltered eton bred nepo baby. Go have a controlled accident in the controlled substance cupboard. You have 0 skin in the game and 0 idea what life is like for the average tranny internationally. Clearly.
>>43740698
Snake.

>>43741974
medical malpractice related death is the top 3 cause of death period.
on top of that shrinks will irrevocably label you as socially unadaptable for life, give you lobotomy medication and state-mandated brainwashing sessions every week just because you show the slightest inkling of actual free thought and humanity. all this while both mental and physical health doctors scoff at your suggestions and jot down everything you say to share it with everyone else involved in their circlejerk 'i learned the name of every bone twenty years ago and my computer still runs windows xp while I click on Google ad search results but trust me I'm the expert and ultimate truth here and you could never open a book and comprehend these things cause we give em speshiul naymmms!' profession and ESPECIALLY to suck big fat pharma dick every night before they drive home to their family. These people are all opportunistic hardcore conservatives that are in it for nothing else but the money and I'm tired of pretending otherwise.

>>43739223
aly DESERVES lots of money, hugs and kisses

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>>43737537
>2026
>i am forgotten

>>43741960
Sorry to keep bothering you with questions but from what I've described, do you think I have some mild EIS? I'm not really sure what that would look like transition/lab work wise. I know I could look up symptoms of this but I'm curious if there was something specific that made you say that. Like I said, my transition has seemed to be at least somewhat okay so far so I'd be surprised if I had that but idk. Also, to be clear, you just mean than SHBG and E tend to rise and fall in conjunction with one another correct?

I've been putting some serious thought into going to med school lately. I already have degrees but I dream of pivoting my life and getting access to medical supplies and the ability to perform some large scale studies to answer my own questions. We all deserve much better medical treatment than we have access to and I wish I could do something about it

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>>43742369
lol
I guess powers realized that trans have no money and doesn't want the legal scrutiny of treating them

>>43742847
there is a lot of money in helpimng men achieve big, fat, juicy, throbbing erections again, huge veiny ones, dripping with anticipation, you know
that and he resents trannies

>>43734648
Its hillarious that the redditlett linked wikipedia as a source instead of the source the wikipedia page used and usually links to

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>>43743068
oh yes anon thats so fucking hilarious

>>43737508
she’s in this thread; her profile went private afterward

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>>43743166
is she rly gonna kill herself over snark on an indian metalworking forum
anuuu chill we all get rejected sometimes, criticism, as much as it hurts, aint worth dying over, especially from rando anons, pls try not 2 hurt urself

>>43742770
Do you know what your LH values come back at?
Your SHBG being high-ish sort of argues against estrogen resistance.
Yes. Estrogen drives the liver to produce more SHBG. Testosterone drives SHBG down. It's just sex hormones aren't the only things that affect it.

>>43742076
You seem like you'd benefit from talking with a doctor.
>>43741733
Presumably so you don't die.
>>43741944
No.

cis women's natural range peaks when injected with BBC

>>43741102
Because getting it involves outing yourself to someone.

>>43744034
My LH is 2.3 mIU/mL
My FSH is undetectable and I thought they usually go hand in hand but that could be wrong

I'm going to be making a concerted effort to be healthier soon as I'm almost out of my recovery period from my pectus surgery and I can finally start working out again. I should probably stop drinking as much too. I'm hoping some lifestyle changes might even out my labs a bit but who knows

>>43734648
>antiandrogen, which unfortunately also supresses some aspects of estrogen therapy
?

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>>43745131
problem tranny?

>>43735454
Yeah but my e levels were like 3100 pmol/L

Idk if im a passoid but oh well

>>43737465
Powers is now obsessed with PFS

>>43743108
Thank you anon it made me very joyful knowing they typed all that and still didnt bother to click 2 links deep!
So silly!

>>43739567
Truest part is getting fat so estrogen works.

Suppressing testosterone is a variable.

Organ efficency depends on lifestyle and genetic factors.

But trusting the doctor? 95% of British doctors surveyed said they were very unknowlegable about trans healthcare, and of the 5% that said they felt confident, 4% could not anser basic to intermediate questions correctly.

This thread knows more than 99% of British GPs

>>43745256
Updoot!

>>43739767
Best advice here. Get orchi or srs, take estrogen.

If you add progesterone, increase estrogen to offset any androgenic effects of prog.

It really is this simple for the vast majority, the details matter to people with idiosyncratic issues

>>43741965
>do you really need any more indicators that HRT is working?

Passing

Wild reading this thread. 16 years hrt here

>but I've been on hrt 4 months and i read on reddit that you can cycle between estrogen and test to increase feminisation

Stop it. Stop doing this shit. Get an orchi or srs. Take estrogen, take it consistently, dont skip doses, dont be lazy. Do this for 5 years.

F I V E (5) years. Then *think* about adding in new stuff like pio and prog. Dont try wacky stuff like putting testogel on your dick. You're a woman. You should be glad its shrinking (it should be gone).

>but i want my dick to keep worling!

Then you're not trans, and thats cool. Its ok to have bodily autonomy and not be trans, but don't complain you dont look like a passoid when you're doing crazy stuff. Transition is a verb, not a noun.

>>43745183
wat i dont get it. i thought they meant like antiandrogens supress feminization in trannies did i misread am i fried

>>43745714
i think she meant that high testosterone is bad, but wrote it in the dumbest way possible, if... she just doesnt genuinely think AAs are bad lol

>>43745384
>prog
The conventional wisdom is to start at tanner IV, why wait for 5 years?

>>43745295
>If you add progesterone, increase estrogen to offset any androgenic effects of prog
biggest retard ITT. sincerely you should shut the fuck up forever.

>>43742106
i'm 14 and this is deep

>>43745998
Enjoy having a man face

>>43745853
Because thats about how long cis puberty lasts.

You want to maximise all potential breast growth with just e. Plus weight cycling affects breast size. One you start prog, any potential growth from e stops

>>43746238
read a book nigga

>>43735454
every passoid I've seen was on diy mono

>>43745384
>>43746238
girls with delayed puberty are always given prog 1-2 years after estradiol is introduced, because this is how it works in normal puberty. i'm sorry you got hondosed, but don't try to ruin other trannies' chances out of spite

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>>43734648
i know it's hard for autists like you to grasp, but it literally doesn't matter whether your estrogen is at 200 or 1000 pg/ml. Biology is not a video game you can minmax and hormonal interactions are far too complex for doctors (and especially you) to determine precisely enough for goofy shit like this. An average pregnant woman has levels above 15 000pg/ml, do you see pregnant women growing beards? no, the only effects of such a massive dose are slightly bigger tits and a dark line on their belly.

Also
>>43734780
>>43734797
>>43734863
>>43734879
Picrel shows how varied the average levels of a cis woman are. 300-500pg/ml consistently is very likely, and the fact that yall are so surprised at this shows your autism yet again. Averages are not concrete and Human biology can't be quantified this easily

>>43747269
girls with delayed puberty try to fix their underlying problems before exogenous hormones. cis girls NEED progesterone to prevent endometrial hyperplasia. prog shows up after 2-3 years of puberty at low and really inconsistent levels. nta, the other anon is retarded

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>>43747327
>An average pregnant woman has levels above 15 000pg/ml, do you see pregnant women growing beards?
oh. my. god.
>Picrel shows how varied the average levels of a cis woman are. 300-500pg/ml consistently is very likely, and the fact that yall are so surprised at this shows your autism yet again. Averages are not concrete and Human biology can't be quantified this easily
picrel

>>43747373
Thank you for repeating what i said and agreeing with me. and even adding a pic that proves my point

>>43747361
>cis girls NEED progesterone to prevent endometrial hyperplasia
ofc, but it also has other effects. are you saying it doesn't affect breast growth or the brain at all?

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>>43747390
>300-500pg/ml consistently is very likely

>>43747399
no im saying that cis girls NEED progesterone to prevent endometrial hyperplasia

>>43746367
>>43747269
>>43747361

I pass and you don't. My words are therefore more important. Take estrogen for FIVE years then add prog.

Stop giving out bad information to create more hons

>>43747630
>I pass and you don't
post face, bobs and vagene

>>43746238
>what is breast involution
>>43747327
>black box biology
people need to educate themselves enough to 'debug' their physiology aka. test and adjust regime based on feedback (subjective interpretation/satisfaction with results) until they find something that works for them
the problem is 95% of trannies aren't psychologically or situationally capable of doing this

>>43740550
for me that's at trough. But yes, being at 200 pg/ml or higher at trough implies higher levels over the week.
I measured mid-week once and my levels were at 586 pg/ml 3 days after injecting.
That was 3 years ago. No issues so far.

>>43748935
that's with 6mg/week injectable EE, just to be clear.

>>43745384
>Dont try wacky stuff like putting testogel on your dick. You're a woman. You should be glad its shrinking (it should be gone).
was it really necessary to be snarky there? :/

>>43745036
I'm not gonna lie—the worst transphobia I've personally experienced has been through the medical system. And at times it's been horrendous. But the doctors willingly prescribing hormones to trans people are less likely to be like that.

But ALSO if estrogen works on you at all…I was male-failing consistently within 10 months of hormones, and I did a slow sublingual ramp. I confirmed complete testosterone suppression at 8 months. That trajectory is unusually fast but my point is the effects of hormone therapy are visible to others. You should be prepare

Under different circumstances I absolutely would inject bathtub estrogen but I think it's worth it to go to a doctor to not have to do that.

That said, shoutout to the urgent care doctor who, when I came in for injuries sustained when I was SA'd, opened with: "So you're telling me you have a penis..."

Anon it did not get better from there. She described the man as a "new sexual partner" and kind of chastised me for not getting tested for STIs *before* being assaulted. She misdiagnosed me with herpes and made it very explicitly clear she did not believe a word I told her.

>>43739567 I hope you're still around to try to understand why people are like this.

>>43745114
Yeah I'm cutting back on drinking too. I was going through it for a bit.
That is a little bit wild—500pg/mL estrogen and still LH > 2.
If you have any chance of getting it prescribed and being able to afford to fill it, I hear some adults end up on puberty blockers (GnRH agonists). That could be an option.

I think FSH is usually easier to suppress than LH. I remember that jumping out to me because I had the opposite relationship: cratered LH but inconsistently suppressed FSH. (But with T values between 6-14ng/dL so nobody was really worried about it.)
>>43747373
>very likely
Consult your own graph. Even the 95th percentile line regularly drops below 300. Random samples are NOT expected to stay above 300 in most women.

>>43749015
I accidentally some words.
You should be prepared for your body to out you at some point.

>>43749015
>I was male-failing consistently within 10 months of hormones, and I did a slow sublingual ramp. I confirmed complete testosterone suppression at 8 months. That trajectory is unusually fast but my point is the effects of hormone therapy are visible to others.
that's amazing progress.
It took around 2.5 years for my body to start vaguely resembling a woman's, and I only started male failing more often after FFS. T has been fully blocked since day 1 (thx cypro)