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>>44959372

op you dropped this
https://rentry.co/hrtgtemp

>>44960626
glad to say i'm the very proud owner of the rentry even though i lost the edit code
i know i can't prove it but i love seeing people spread it around
did get banned for it for a little while though

I've never done estradiol before but what is the difference between that and just taking phytoestrogens instead?

>>44960645
oh
maybe make another one then incase anything changes

does anyone know what the standard cis male testosterone range is

>>44959372
How much of a pain in the ass is getting a private blood test? I just wanna know how much effort I'm going to have to put in.

can someone send the invite to the pio discord thanks

>>44961040
https://discord.gg/xWSEJGhWx

>>44960729
depends where you live, where im at it was quite simple and fast, honestly too expensive to have been worth it though

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>be me, Symphony Labs

>never inspect vials before selling
>claim that hair in vials was due to "one bad batch",everyone in the community starts replying to anyone complaining about hairy vials with the "one bad batch" explanation and that the issue was already fixed for future batches
>tfw current batches still have hair
>claim that loose vial caps that fall off was due to manual crimping
>still have loose vial caps one month later
>self advertise on wikipedia by putting my vial picture on the estradiol enanthate page
>put photos of my lab on the wiki page for DIY HRT
>join the transdiy discord and brag about opsec sensitive business practices
>somehow the mods are ok with this
>hire a new shipper even though she lives with her chud parents
>packing 50 orders a day in her living room after her family sleeps
>chud parents find out and kick her out
>not my fault
>hire a new shipper to clear backlog
>new shipper shits herself and creates a 4 week backlog
>claim customers are lying to people about a 4 week backlog
>claim customers are lying to people about taking preorders
>its the customer's fault for lying about our practice
>get exposed that all uk domestic orders were preorders, have to offer refunds for anyone who ordered from the uk
>left uk customers waiting over a month before admitting that i let preorders pile up for vials that weren't in the uk warehouse yet
>customer data leak exploit was brought to my attention in May
>lie about fixing it
>tfw customer data was leaked 2 months later because i never fixed the api exploit after someone already notified me
>somehow this is everyone else's fault for being mad that i didn't fix the exploit for 2 months
>somehow the entire community still has my back because im so good at community outreach and PR
>make 20k in earnings every month
>everyone still treats me like a small time brewer doing it out of the goodness of my heart
>now have 8 week backlog
>still taking preorders
>tracking still broken
>still winning?
>tfw

hyper specific question incoming:
i'm 3 months in diy and getting on my first blood test, but i fucked up and forgot that the day i was intending to get it done lines up with a public holiday when all the labs are closed.
would it be better to do my injection as normal tomorrow then push the test another week, or just delay my injection by one day? are my levels likely to be dramatically different 7 days post-injection vs 8 days?

>>44961913
you were intending to test on monday next week because that's your regular injection day, and now you plan to test on tuesday the week after?
your levels will not be dramatically different, no, and that's also why you can delay your shot for a decay without affecting your transition. it might be best to align it with 7 days to be more confident in the results. hrt comes with ups and downs you dont wanna get paranoid about being underdosed due to an uncertain test.

prob not dramatically different, especially if you're not on valerate, but desu if it's not a problem to do next week i'd personally just do that to get a bit more accurate results

>>44961933
>>44961952
i meant that i was intending on doing it on monday since that's injection day, but since i can't i was gonna just get it done the next day (and delay my shot by a day, ofc);
i'm taking 6mg/week estradiol enanthate so i think it's probably fine either way idk, i'm very bad at math but according to the injections simulator i should be at like 300 pg/ml trough by this point

>>44960657
ok so oversimplifying a little, hormones are considered signalling molecules in your body. by attaching to a one of the thousands of receptors on / in a cell, they tell the cell to perform some function. for example, absorbing glucose from the bloodstream or proliferating.

these receptors have specific shapes, such that only certain molecules can attach to them and produce a response. some molecules fit easily, some fit less easily, some don't fit at all. similarly, of those who do fit, the manner in which they fit determines the magnitude of the response. basically even once you're through the hallway, you still need the right key. some molecules can jam receptors without actually activating them (antagonism), resulting in a weakened signal overall. others produce only a partial activation (partial agonism), while some produce full agonism.

estrogen is a family of molecules and hormones with varying abilities to fit into (affinity) and agonize (efficacy) estrogen receptors, the two main types being ERα and ERβ. phytoestrogens are partial agonists of ERβ with low affinities. meanwhile estradiol is a full agonist of both ERα and ERβ, with 1000-10000x higher affinity, meaning it is much more likely to latch onto the receptor and trigger the cell to behave strongly a certain way.

you would need a far greater dose of phytoestrogens to produce the same receptor occupancy (% of occupied receptors) as a smaller dose of estradiol, and the efficacy would be far lower no matter how much you took. it's not a pure numbers game with activated receptors, and thus there is no dose of phytoestrogens that can produce the same degree of feminization as estradiol.

>>44959372
i take hrt for years and voice trained and now malefail despite boymoding in a gigaconservative town at every occasion, but i still do not pass. i just wish i could transition.. this is hell

>>44962037
Thanks for the explanation.

mm snax

how often should I inject enanthate?

>>44964456
once a week is good. you can stretch it to like once every 10 days, but imo it's just easier to not miss injections if you always do them on the same day of the week

How many different spots should I rotate between with IM? Like is it fine to just rotate between my left and right thigh in the same general area or should I be getting wacky with it? I'm not gonna hit the exact same spot either way.

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I overdosed on estrogen ethanate about four months into my hrt regimine (yes I'm a fucking dumbass IK) and had a estradiol blood content level of about 264 pg/mL.

now I read on the old diyhrt wik that there was no good evidence that hondosing in the early stages was effective at encouraging breast growth (https://diyhrt.wiki/transfem) but i found this article today (https://hrtyaku.com/en/breast-development/) suggesting that I may have cooked myself by causing the breast tissue to differentiate prematurely. my doctor told me that i was in an acceptable range however.

did i fuck myself? idk who to believe. any of you nonas have a similar experience?

I went off of my 200mg spiro three months ago and I just don’t know. I got tested last week and my T is still suppressed <10 pg/dl and my orgasms are dry but I just feel… different. And more muscular. I have felt way more suicidal and honestly just wish I could get on Cypro again but it’s so fucking expensive. Could DHT levels be to blame here? Is 5mg E Valerate dosing once per week really enough?

My results have never been all that amazing over the last 5 years on or off spiro so idk. I think I gave a thyroid issue that majorly fucks with my hormones despite starting with a fairly androgynous face/build

>>44964456
lena's recommended dose for 40mg/ml is .3ml per 14 days

>>44966490
measured breast to underbreast difference. 39 to 37. about b cups. leading me to assume most breast growth is set and i avoided catastrophe.

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>>44967106
idk 14 days seems a little insane to me. maybe if it was undecylate

>>44964456
Once every 7 days, can stretch it to 10 if you need but consistency is key. Start with a dose of 4mg (if you have a 40mg/ml vial and a 1ml syringe, draw up to 0.1ml), get blood tests done in 3 months and see how you go

>>44967317
I thought people were suggesting 5mg these days.

>>44967330
4mg is plenty for suppression on monotherapy. Most people see 5mg as wasteful. The reason for the increase is insecure babytranners wondering why they don't have double-D cups 3 shots in, pay them no heed

If your subq injection leaks then how fucked are you (asking for a friend)

>>44966490
there's no consensus on this. https://diyhrt.info/transfem/dosing/ recommends keeping your trough levels in the range of 200-250 pg/mL for testosterone suppression purposes so I'd say you're more than fine. if you ask me if you want the biggest tits possible get orchi day one and keep trough a little above 100pg/mL forever but no one does that
also that website looks kinda ai generated lol

>>44966490
>overdosed
>264 pg/mL.
oh my god the healthcare system is terrible, that's a completely reasonable level....

>>44967281
I do that and it works fine. levels are more stable with higher bodyfat% btw

>>44967330
it may be necessary depending on the person, but most are good with 4

>>44968494
depends how much leaked out. fill a used syringe with water the same volume you usually inject and squirt it on your skin. if it was a significant fraction of what that looks like consider injecting more, otherwise you're fine

>>44966490
>"the more you take, the faster they grow"
literally no one says this

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>>44959372
Got my results back a couple of days ago, does it look good? (taken 5 hours before usual time of weekly injection)

My regimen consists of: 4mg EEn weekly, 3-monthly 10.8mg Zoladex implant (test was done at just over 3 months since last implant, had the next implant done an hour after these tests), and 200mg prog 2 weeks on/2 weeks off.

Oestradiol: 642 pmol/L (175 pg/mL)
Progesterone: 42 nmol/L (13.2 ng/mL)
LH: < 0.3 U/L
FSH: 0.3 U/L

Testosterone: 1.0 nmol/L (29 ng/dL)
SHBG: 71 nmol/L
Free Testosterone: 11 pmol/L (3.2 pg/mL)

Someone in the DIYHRT server said that my E2 was a tiny bit too high considering I'm on a GNRH agonist, just looking to get some more opinions

I've gotten kinda depressed since around when I started cypro. it's a pretty low dose (12.5mg a week) though so idk if it would be that. should I go back to mono

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>>44959372
[repost of https://archiveofsins.com/lgbt/thread/44952491/#q44953774, originally posted + ignored in mtfg when this thread was down]

NEW SYMPHONY LABS OPSEC SITUATION

>symphony vial held at customs
>call my postal service abt it
>they refer to it as "your parcel from [full male name]"
>first name sounds similar but not identical to lady who's been taking my emails
>hmm... weird, clip that part of phone call, forget abt it

>later personally confirm 2 other women encountering the same opsec issue
>since they've physically recieved their packages, they also have return addresses
>check both unique ones on google maps, confirm they are real housing
>can't prove either way if the names are real or fake
>get in contact with valerie
>she has direct line to symphony
>they are aware of my emails abt this (they'll prob know exactly who i am just from this post), are "going to reply", don't get around to it
>also find out one (1) person is managing their entire support inbox
>also find out they are STILL dealing with backlog despite not acknowledging it (everything's shipped, but not all received yet, so that's still being monitored)

>this has happened in 3 confirmed countries (US, UK, AU)
>there are prob way more packages with potential dox out there
>both my attempts at private comms (emailing symphony support 3x, DMing valerie) have gotten no response from them

unlike the last person to publicise a symphony opsec special on 4tran, i won't spread the info and heavily encourage anyone with a similar encounter NOT to do so either, as that won't accomplish anything positive. this post is unfortunately the only remaining method to hopefully force a response.

keeping this hidden instead of sounding the alarm now might cause far more long-term damage, if the worst case here is true and all the dox is actual employees.

>>44966490
>264 pg/mL
lmao thats nothing. I had mine over 500pg/ml and gave myself morning sickness.

Does anyone know sites where you can use crypto to pay for needles and syringes?

>>44969891
why would you need to do that

>>44969891
where do you live where that is necessary? just go to a pharmacy or something. hell most cities have places you can get them for free so meth addicts don't get aids

is gel monotherapy actually achievable or is it a meme? i am currently doing ev injections but i kinda want to swtich to making my own gel so i don't have to worry about stock anymore

For someone new to this, is there a safe way to order HRT such that I go pick it up from a PO box or something? I don't want them knowing where I live.

>>44971011
Unlikely....Making your own injections is really not that much harder desu

>>44971040
some do poste restante (general delivery)

>>44968908
if you're on GNRHa then you'll be fine at around 100pg/mL E2 since you don't need your levels to be high enough to suppress testosterone, 175pg/mL isn't bad though. you can try doing 3mg weekly instead and see how you feel and see where your levels end up, you'll waste less EEn that way. i don't see anything wrong with your levels though.

>>44971040
i had it delivered to a PO box in the US and it went fine

>>44969263
are you retarded enough to think symphony labs is putting a team member's actual legal name on the return address? why wouldn't you think it's an obvious burner name

>>44969263
valerie and symphony are close friends, you will never catch valerie ever criticizing symphony. she was the one who tried to hide the customer data leak, minimize the severity and sweep it under the rug.

>>44969379
larpers, I had over 3000pg/mL for years and felt nothing

>>44970057
>>44970764
i've never been to a pharmacy that doesn't ask you for a prescription if you want needles, heck i have a family member who's diabetic and they're constantly having issues getting more than the bare minimum.

>>44973097
cant you just order them online without prescription?
like amazon? amazon isn't great but something similar, here i have a national place that sells stuff like that which is pretty okay

>>44971069
i feel like way too much can go wrong with that

>>44969263
>symphony is incompetent
>sky is blue
have anything actually interesting to share with the class nona?

>>44973681
only if you're a retard. all it takes is to sterilize everything and be careful, and even if it goes wrong, at most you'll get an infection that sucks but won't kill you. which is a thing that can happen with commercial estradiol too (such as when coring the vial or not using proper injection hygiene)

Recently started injections of estradiol valerate every 5 days
Is a 0.18ml injection loo low or too high? Should I use something else to lower T levels? I was on lenzetto with spyro not so long ago but I'm pretty sure it did literally nothing so I'm taking blood tests next month anyway to check levels and see adjustments, but I just wanted to ask lol

>>44974650
>Is a 0.18ml injection loo low or too high?
First of all, learn what a dose is. mL measures liquid volume. That's not your dose, which should be written as "mg/period of time"
>Should I use something else to lower T levels?
No. EV is perfectly capable of monotherapy, and spiro in any context outside of gel or pills is borderline medical malpractice

>>44974666
>>44974666
Oh, OK
So with a concentration of 40mg/ml in the vial I would have a dose of 7.2mg of estrogen every 5 days if I inject 0.18ml of liquid volume, correct?

>>44974755
Yes!
That's a reasonable dose to start, maybe on the higher end but not crazy. Whether it's too high or too low you'll be able to determine when you see your levels. Make sure to get the test during your trough (injection day)

>>44969263
they go through a new set of shippers/customer support every few months. they're like disposable cattle to the owner so i dont think symphony really cares when low level troons get doxxed

what form of estrogen and roa is ideal with bica should i start out with monotherapy and introduce bica? When? How come nobody talks about bica as much?

>>44969263
Obvious FUD larp post. No homebrewer is putting their real name on the return label. You're trying to start drama with nothing at all.

>>44972466
Then why did symphony and valerie never respond to the opsec leak? They have a fulltime support person. Wouldn't take a lot of effort to just reply that it's a fake name. But they keep intentionally hiding the truth because THEY PUT THEIR REAL NAMES ON RETURN ADDRESSES

>>44969263
Fuck off peachy. I know that herafags are paying you off to slander symphony. I hope that blood money feels good.

>>44969263
dumbass, homebrewers use fake names and shipping addresses. you're just making a fuss for no reason. calm down

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Can someone please help explain to me what the realistic drawbacks are from having levels like this? I am finally seeing some progress that has been sorely lacking, is it safe to continue?

probably the smallest market out of every market I've ever seen and there's somehow drama

what's the safest way to bring hrt over sweden norway border without being searched?

>>44977916
sweden norway doesnt do border searches like 99 percent of the time right?

>>44978016
they've been doing it the last 3 times i've been there

Holy fucking shit.

Hera HRT underdosed vials by 20 mg/mL for May batch. July batch is okay.

TransHarmReduction latest test: https://www.instagram.com/p/DeJroFJDt7L/

TransDIY discussion: https://www.reddit.com/r/TransDIY/comments/1wz0kxe/hera_hrt_may_2026_batch_serious_concentration/

>>44977762
High shbg and anecdotes, mostly. If it works for you, it works for you. Worth noting that community pioneer Lena ovedoses herself to hell and back, and seems to be fine.

>>44978819
What the fuck, hopefully they offer full refunds.

>>44978819
>Order my first vial in early September
>Got the stealth non-label
>Might be getting hondosed
>Have no way to know because I'm poor as shit
Fuck my life

bump

>herafags paying people off to manufacture conspiracies about shippers being doxxed

>symphonyfags sending off fake diluted hera vials to transharmduction to ruin their image

tfw this is the state of the homebrew market now

>>44977762
usually having extremely high levels means you're wasting estrogen, plus shbgmaxxing like the other nona said. if you truly are only seeing progress with levels that high though i'm not gonna tell you to stop, just be careful

>>44978819
It’s really interesting to me that every time a Hera vial is tested by a lab that purchased it themselves, the concentration comes back basically perfect. Yet whenever a supposedly anonymous customer submits a Hera vial for testing, the concentration is suddenly way off.

There are obvious adversarial incentives at play in this space, and people shouldn’t blindly take these results at face value. There’s very little financial incentive for a seller to intentionally underdose their own vials, but there’s a massive reputational incentive for someone to submit an intentionally adulterated competitor’s product and make them look bad.

At least consider the possibility that some of these results are being manipulated before treating them as definitive evidence. Open your fucking eyes, people.

is my nipples being very puffy (not just perky) a good thing? almost 4 months in

For all the complaining about shitty protocols & not using submicron filters Lena remains undefeated. Low time preference trannies order at least 4 months in advance and don’t care about shipping time rather than playing Russian roulette with US brewers who will either accidentally dox you, hondose you, send you cat hair, or just forget to add the API completely.

>>44981396
slava ukraini

>>44977903
troons

>>44978819
I ordered my vial on july 15th. Should be part of the july batch right?

>>44981190
yes it's very likely to be a competitor trying to ruin heras reputation.

i bought my vial from aurelia and it's coming in a month
are they also shit/is it going to be seized
(britbonger)

>>44981190
Starting around July, Transharmduction began sourcing vials for testing, with the testing taking place in August. If you look at Hera’s two test results, both were completed in August.

Transharmduction tested five homebrewers: Mayaa, Sera, Calyx, Aurelia, and Hera.

What stands out is that Hera is suspiciously the only homebrewer who had two separate samples tested.

I know for a fact that the vial samples from the various homebrewers were sourced by Transharmduction through their own methods. However, the May Hera sample was independently submitted by a supposed “customer.” That sample was adulterated and contaminated intentionally.

Hera’s vials have consistently tested correctly, with the only other exception being a sample tested by exogenous.fun, which was also independently submitted by a customer.

To me, this looks like another attempt to damage Hera’s reputation. Someone submitted a deliberately compromised sample, got a negative test result, and used that result to discredit Hera. And unfortunately, it worked.

>>44982592
I got one vial from Hera and they were wonderful...

so wait what does shbg actually do I tried to research this earlier and it didn't help

>>44982592
madness

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>>44982592
100% this. I’m surprised people aren’t willing to consider that a competitor could simply uncrimp a vial, adulterate the contents, and then recrimp it.

Competition psyops have been a thing in this scene for months, if not longer than a year. Remember when Tea was constantly complaining on this very board, on hrtgen, and all over Bluesky about how evil the homebrew scene was, and how her competitors were supposedly running character assassination campaigns and making up lies about OGL?

This would just be the next step in the US homebrew market: actually adulterating samples of a competitor’s product. It also wouldn’t be particularly surprising given that several new US sources have cropped up recently.

I think everyone has also forgotten about the recent campaign on Twitter and Reddit where someone fabricated a Janoshik test claiming that Hera vials contained anabolic steroids. Tea even called it out on her Bluesky, and Hera had to address it in a statement on their blog.

There are clearly still people out there who have an incentive to damage Hera’s reputation for their own benefit. Given that people have fabricated claims and run psyops against Hera in the past, it’s entirely expected that they would keep doing it until they eventually succeeded, which it seems they now have.

>>44983833
>symphony still generally regarded as competent

>>44983833
vial decapper is $20 on amazon btw you don't have to even be a brewer to pull this off lol

why do blackies make fun of me when i use my pooping bucket?

>>44973097
I live in australia and they hand this shit out like candy for all the meth addicts

Even if somebody was messing with hera by submitting fake vials can somebody please explain to me how it's fine for them to be selling vials from batches where only the raws were tested? Am I reading their reply wrong or? And now they're reshipping but only for people who bought in may and early June but people have been posting saying they had vials marked from the may batch that they received after ordering in August or September. Ofc my stupid ass got a stealth vial early September after ordering late August so I have no fucking clue if my vial would have been affected because they dont mark stealth vials with literally anything. It feels so ridiculous that im having to fall back on my backup vial from fucking pawsnax of all places

>>44984612
no one does per batch testing anymore, not even symphony, hera recently tested their September batches so at least they're picking up the slack.

Honest, forthright Hera blog post where she admits her mistakes and takes full responsibility, even though this is ultimately another lab manufacturing controversy.

Vs. virgin Symphony, who always seems to blame everyone else and accuse customers of lying in her blog posts instead of taking responsibility for her own mistakes.

Seriously, look at the difference in how Hera responds to controversy in a calm, level-headed way versus how Symphony literally blames everyone except herself. Kek.

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>>44961913
>>44961981
so i got my levels back, im really horrible at math but this is really bad, right?
E2 ~76.3 pg/mL
Testosterone (Total T) ~80.8 ng/dl
i should probably raise my dose from 6mg/week if my levels are menopause-tier at trough?

>>44984693
If it's so uncommon that nobody on the market is doing it wth are they backpedalling into doing it only now after there was a controversy like its nothing before even confirming the batch is cooked? This happened just as I started prog too (100mg suppository/day) and my libido has shot through the roof despite having increased my dose to 6mg/7. My t was tested at like 15 a few months ago but all of a sudden I'm feeling the need like 1-3 times a day when I was at like 2 per week if I felt like it before and there's no way prog can account for that surely so now I'm actually worried I've been dosed at 3mg/7

>>44984830
raise your dose yeah

>>44984807
Well I mean if you actually read the blogpost this whole ordeal apparently got the actual Hera to leave. The rest of the team is continuing but it's not like there wasn't real damage.

>>44984996
so I'm getting that there are three possible scenarios:
>hera actually fucked up, felt guilty and left
>faked, hera bought it, felt guilty and left
>faked, hera freaked out at being targeted like that and left
second seems most likely to me

>>44983833
this is something that people have speculated might happen for a while. i would not be surprised if hera got played
>>44985045
we've had brewers on this board talk about competitors and other brewers inciting controversy was the worst part of being a homebrewer. it's very possible the stress finally got to her, in combination with all the other shipping problems hera has had (especially with hundreds of vials just being lost in the chicago usps center)

Please don't ever leave me in a situation where I have to get my stuff from Pawsnax.

>>44985317
because i dont know if i should double my hera vial or not im probably going to have to dip into my vial of ponyshit rose oil ;(

Insanely funny to me hera is now going to do per batch testing while symphony has silently stopped doing per batch testing even though they make like 10L batches lollll and all their vials that do get tested are like 37mg/mL for some reasons

>>44985750
You don't have to lie, symphony tests each batch they make, they literally advertise it on their main page.

>>44985781
>symphony tests each batch they make
No, they dont.

>no cypionate testing since June of 2026 despite a recent restock
>no undecylate concentration or GCMS testing since May of 2026 despite SEVERAL restocks since then.
>no valerate testing since June 2026 despite recent restocks
>gap in enanthate batch testing from June to September of 2026
>recent enanthate tests all lack concentration test results (due to test results showing under 37mg/mL)
>batches 16 to 22 were never published
Symphony has had inconsistent testing for a LONG time, and they still refuse to do per-batch testing for every batch they produce, despite falsely advertising on their main page that they do.

It honestly amazes me that people haven’t noticed this yet. I guess people are just too lazy to actually look at Symphony’s own testing page and see the blatant contradiction for themselves.