Prof. Kate Adamala and her team at the University of Minnesota have built SpudCell, a cell-like system constructed entirely from known chemical components that can perform a complete cell cycle.Unlike earlier work on minimal cells that carved down living cells, SpudCell is built entirely bottom-up from individually purified, non-living components. It is the first time such a system has demonstrated a complete cell cycle.https://www.biotic.org/research/spudcell/Replicates a biological cell's life cycle: SpudCell is capable of selection, genome replication, growth, resource acquisition via feeding and genetically encoded division.Cell division without a cytoskeleton: Natural cells divide using internal scaffolding called a cytoskeleton, which has been a bottleneck in synthetic cell research. SpudCell sidesteps the need for a cytoskeleton with proteins that crowd together on the membrane surface until the mechanical stress makes the membrane split.
>>538172532Thanks for sharing anon, that's absolutely fascinating. I wonder how far they could take it, to demonstrate more of the functions of biology.
How will young earth creationist tards cope?
>>538172532i guarantee if I look into this I'll find some living cell derivative components. 100% guarantee.what they call "non-living" components were probably taken from dead fetuses
>>538172806>>18555655>>18555655>>18555655This.
>>538172806by outlawing carbon lol
>>538172901Aww dang it. I told some dude Jesus's miracles were all normal human feats and he just started going off screaming about his "testimony" or whatever.
>>538172768What frightens me is that if it becomes autonomous and can live outside the laboratory what havoc will it wreak upon a hapless defenseless world? Not this iteration perhaps but future ones....more vigorous, agressive ones..Kurt Vonnegut's Ice 9 in biological form?
>Katarzyna (Kate) P AdamalaIs this a slav?
lets train it to eat flesh and release it
>>538173006Maybe like Russian Turkish ish ?
>>538172995Yeah, I was thinking of some sci fi horrors too. Biomemetic gel that turns everything it contacts to gray, replicating goo.
>>538172532>SpudCell sidesteps the need for a cytoskeleton with proteins that crowd together on the membrane surface until the mechanical stress makes the membrane split.Literally grey goo. Shit will just mutate to consume everything.
>>538173006Yup, first name seems polish
>>538172995I wouldn't be so scared of for this one... What's really scary is mirror-image life. Life built from chemicals that are the mirror image of the ones we use. It's thought that it would absolutely devastate the ecosystem and destroy our bodies with no way for our immune system to respond, and there's currently no regulation for studying it.
> SpudCells have the genes to make ribosomes, but for unclear reasons do not make them. Ribosomes added artificially work for a time before ceasing.[1]> SpudCells are also incapable of dividing on their own. Division has been accomplished in the lab by adding streptavidin for single division events and the use of a mechanical separating mesh for subsequent ones.[2]
>>538172768Literally a self replicating piece of innate material. If it escaped a lab setting the planet is fucked beyond belief. The scientists that did this need to be arrested. Imagine this replicating in field, in your lungs etc...stupid fringe science. .. absolutely zero benefit to making this
>>538172894>i guarantee if I look into this I'll find some living cell derivative components. 100% guarantee.>what they call "non-living" components were probably taken from dead fetusesIt's not a fully autonomous, self-sustaining living cell. It requires external feeding (ribosomes and other components aren't self-produced yet), doesn't evolve spontaneously (mutations were introduced), and has limitations like incomplete plasmid inheritance. Researchers explicitly call it a step toward artificial life/chassis, not life itself. It's chemically defined at assembly (known concentrations of purified parts), assembled bottom-up from non-living componentsOn the "living derivatives" or "dead fetuses" claimThis appears to be a misconception, possibly confusing:PURE system ribosomes/tRNAs: These are typically highly purified from E. coli (bacterial cells) or produced recombinantly. Commercial and research PURE kits use individually purified recombinant proteins + purified ribosomes/tRNAs. No evidence of human fetal material. Ribosomes are complex macromolecular machines (rRNA + proteins), but once purified, they're biochemical reagents—like enzymes in any lab assay—not "living."Critics of synthetic biology sometimes broadly label any biomolecule from once-living sources (e.g., bacterial ribosomes, recombinant proteins expressed in cells) as "not truly synthetic." But that's a philosophical/semantic point, not a factual debunking. The field distinguishes top-down (genome-reduced living cells, like JCVI-syn3.0) from bottom-up (this work: assembling from parts). SpudCell is bottom-up.
>>538173351>mirror-image lifehttps://en.wikipedia.org/wiki/Mirror-image_life#Potential_risks>In December 2024, 38 scientists, including several synthetic biology researchers and two Nobel laureates, warned that the creation of mirror-image life could cause "unprecedented and irreversible harm" to human health and ecosystems worldwide.[3][26] The reversed structure of mirror-image bacteria could allow them to evade many mechanisms critical for immunity and predation that have evolved to recognize natural-chirality structures.[27] As a result, mirror-image bacteria could potentially escape immune defenses and invade natural ecosystems, leading to "pervasive lethal infections in a substantial fraction of plant and animal species, including humans." Given these risks, the scientists concluded that mirror-image organisms should not be created without compelling evidence of safety.[3] Currently, no researchers are known to be pursuing the creation of mirror life; several who had been pursuing it have since renounced it and signed on as coauthors on the 2024 paper.[28]
>>538173437POTD
>>538173437Dude, this is the only science worth doing. Unknown benefits, crazy risks, with agnostic autistic scientists bemusedly going forth with it and reporting back.
>>538172532Oh wonderful, synthetic organisms.
>>538173631>Dude, this is the only science worth doing. Unknown benefits, crazy risks, with agnostic autistic scientists bemusedly going forth with it and reporting back.YES YES YES
>>538173631What benefit would it have? It has as much benefit as going into a cave and wuhan and ramming q tips up a bats ass to make a vaccine for something that has a million in one chance of becoming a pandemic. Because that's how we got covid, because it was a literal Vaccine that escaped
>>538173839we need another skylab
>>538173903That nigga crashed to earth tho didn't it
>>538173903>W01SYO7Wfucking 1 ruining my shot at the widest id ever
>>538173990after awhile, and they let it.
>>538172894Macromolecular self-assembly is perfectly feasible, but probably
>>538172532science being attacked by leftists
>living chemicaland I'm gonna be the first guy to dip my penis in it.
>>538172532why AI didnt do this?
>>538174328Imagine a pocket pussy made out of this that replicates vaginal discharge and periods and pubic hair :3
>>538172532>synthetic cancerokay
>>538174547i want it to give me back my 4skin!!
>>538174632what makes you so sure you had one?
>>538172532>spudcell
>>538172532Now follow the money that's backing/funding it
>>538175051>"Biotic Funding" most commonly refers to Biotic Labs (Biotic), a Tel Aviv-based agritech startup that raised €2 million in a seed round to produce biodegradable polymers from macroalgae. why so antisemtic?
>>538172532
>>538172532It's cool, but I wonder if it's of any use because of AI. When I was a kid, DNA was touted as being an amazing data storage medium, but these days we have hard drives of who knows how many terabytes. Maybe biological cells will soon be obsolete entirely.
>>538172532Cool let's release it into the wild and see what happens
>>538175662everything gets covered in starch
>>538175662It would degrade and die in moments. Nature is extremely inhospitable.
>>538175662>there’s jam coming out of the walls!
>>538172532When it escapes the lab what will they call the disease? Spudvid26? This sounds like some Andromeda Strain shit.
Cool now show me this naturally occurring without interfering with the natural process
>>538172532creationists btforeligion btfoyou all lost
>SpudCells are also incapable of dividing on their own. Division has been accomplished in the lab by adding streptavidin for single division events and the use of a mechanical separating mesh for subsequent ones.The "cell" "replicated" when they physically forced the goop pile into two piles.I see.
>>538172532And some jew will own the rights to do production and probably abuse it. Why should I care?
>>538176783>naturally occurringbitch you are here because cells divided in your useless mother's womb
>>538173466it would have been less effort to just say I'm right.
>>538172532SCIENCE RULES!!!
>>538176850>Replicates a biological cell's life cycle: SpudCell is capable of selection, genome replication, growth, resource acquisition via feeding and genetically encoded division.>Cell division without a cytoskeleton: Natural cells divide using internal scaffolding called a cytoskeleton, which has been a bottleneck in synthetic cell research.God need not apply.
>>538176886Show me a cell making itself from inorganic material I'll wait faggot.
>>538177027they literally just did that with this research kek
>>538177077But i emphasizes naturally without artificially induced bullshit. You still cant do it
>>538172532How can we bypass the FDA to put this in the food supply?
>>538172532>made an intrinsically leaky cell that can only "feed" by poking holes in itself (a-hemolysin)>can only "divide" by chemical or physical damage (but not too much, or it dies)>loose plasmids for all DNA, not even bacteria level> no chaperones, can't make multi-subunit proteins like ribosomeswow, it's fucking nothing, made by people with zero systematic understanding of their own damn field.
