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/pol/ - Politically Incorrect


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When did you realize that the US government has a cure-all for any virus that they've been trying to hide from the masses?
On July 27th, 2011, a paper was published in PLOS ONE describing a novel protein biologic antiviral. It was called DRACO, an acronym for Double-stranded RNA Activated Caspase Oligomerizer.

This research was performed at MIT’s Lincoln Labs and then moved into the Draper Laboratory and was funded by NIAID, DARPA, and DTRA. The Pentagon were after a broad-spectrum antivirus that could cure any viral infection, in case soldiers were exposed to an unknown pathogen for which no vaccine existed (i.e. a biowarfare agent). Dr. Todd Rider’s solution was to come up with a chimeric protein consisting of a dsRNA detection domain fused end-to-end with an apoptosis induction domain. These protein biologics were produced by being cultured in a bioreactor in E. Coli bacteria transfected with plasmids to produce DRACO proteins, similar to how recombinant insulin is produced.

It is possible to formulate different types of DRACOs, such as Protein Kinase R and Apoptotic protease activating factor-1, PKR and FADD, RNaseL and Apaf-1, et cetera. DRACOs all have the same mechanism of action. They take advantage of the fact that many viruses, including coronaviruses, produce long strands of dsRNA when they infect cells and replicate. Even viruses with ssRNA genomes like SARS-CoV-2 do this. Healthy cells, on the other hand, don’t have any long strands of dsRNA in them at all.

This is how it works:

1. DRACO proteins are injected into the subject.
2. The proteins use cell-penetrating peptides (like HIV TAT) to cross cell membranes and enter cells.
3. If there is no viral dsRNA present, the protein does nothing.
4. If there is viral dsRNA present, the dsRNA detection domain (such as PKR) binds to the dsRNA.
5. Multiple DRACOs bind side-by-side to the viral dsRNA.
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The exposed apoptosis induction domains of the DRACOs (such as Apaf-1) bind and crosslink procaspases and force the infected cell to self-destruct.

DRACOs are like little protein limpet mines that enter infected cells and command those cells to undergo apoptosis immediately if they find signs of viral infection, but are non-toxic to healthy tissue. This was proven experimentally in mouse models. They injected mice with DRACO, and then injected them with large quantities of influenza virus. Nothing happened to the DRACO treated mice when they were exposed to influenza. They were fine. In fact, they dissected the healthy DRACO-treated mice and confirmed that the DRACO proteins were non-toxic to uninfected cells.

DRACO proteins conferred practically ironclad protection against viruses that lasted up to a week after injection. All viruses. You see, viruses have ways of suppressing apoptosis pathways in cells, turning infected cells into practical zombies that can’t quite eliminate themselves before they replicate tons of viral particles. It makes a real mess. However, a protein that combines a dsRNA detection domain with an apoptosis induction domain completely bypasses the tricks and loopholes that viruses evolved to prevent apoptosis. Viruses don’t see DRACO coming. It completely destroys the cell the moment viral replication starts, shutting down the infection immediately while it’s still in a small population of cells. If DRACO is administered late, there is indeed more apoptosis and more inflammation, due to the larger population of affected cells. If it is administered prophylactically, before infection, viruses can’t even replicate in DRACO-treated cell populations at all, whether in vitro or in vivo. It puts a complete halt to it.
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Now, with results like these, the logical thing to do would be to engage in more animal testing, experimentally confirm (or refute) the effects, and, eventually, proceed to human trials. After all, in theory, DRACO could be combined with surveillance and contact tracing to completely arrest the spread of a pathogen before it even had a chance to become a pandemic. If it worked, and if it had minimal side effects, it would have become an invaluable tool in the epidemic control toolbox.

That wasn’t what happened.

In 2014, Todd Rider sought $2 million in additional grant funding from the Templeton Foundation to continue his work. However, during a reorganization at the Templeton Foundation, the grant fell through, and he was left with nothing. Desperate for money, he started a pair of Indiegogo campaigns to fund his research that also failed.

https://www.youtube.com/watch?v=Iixl941ZL3E

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0022572
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Dr Todd Rider's website
https://riderinstitute.org/
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>>544097801
Sounds sketchy.
Are you telling me there are no capitalists around trying to fuck with big pharma for a huge payout?
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>DRACO
Based
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If you believe in viruses you are retarded
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>>544097801
If I had to guess why its really not being picked up- it worked great against viruses but in "a few" instances it also caused gigaturbocancer.
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Curing sick people is considered a poor business strategy in the medical industry. That’s not how the Rokafellers set things up
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draco proteins harvested from reptilians
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There's a difference between interdimensional entities that inhabit organic portals (evil humans) and "reptilians" (intergalactic species). They are not the same... One is from another dimension (think stranger things) and the other is from another planet (think Star wars).
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The interdimensional entities are spiritual parasites, what you think of as demons. They only inhabit humans who offer their body as a vessel. They drive a human body as a parasitic worm would take over an insect.

The reptile-looking beings are mortal. They are a different species.
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>>544097801
You occultist fags are retarded to throw your signs at our faces. I won't read your shit, die mf.
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>>544098727
big pharma is the huge payout. if you eliminate the flu, now you can't sell tamiflu, you can't sell nyquill and dayquill, mucinex, tissues, so forth and so on. eliminating sicknesses eliminates money for very large companies. now imagine if they did cure cancer. every oncologist and radiologist just lost their jobs. huge medical buildings that cost billions of dollars are now liabilities instead of assets. you now no longer need tens of thousands of nurses. healthcare is the biggest employer in almost every single state. you cure sicknesses, you take away a lot of money from powerful people.
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>satanic jewish greeting
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>>544099246
>>544099638
He does that gesture because hes a fan of star trek
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This is just an advertising/begging thread. Nice try, Todd.
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>>544100120
>t. larps as an old ass /pol/ identity to shekelgrub and shill his own shitty sites and ebeg

This is NOT Lambright.

This is an attention whoring, grifting faggot with donation links all over his jewtube, whomst is currently preparing to launch this "$120 a month subscription to edit" wiki site, who can not post a thread ID timestamped selfie proving he's Lambright, at first heavily bullshitting and evading it:
https://archive.4plebs.org/pol/thread/542865432/
then moving from that to outright ignoring any mention of it and hiding:
https://archive.4plebs.org/pol/thread/542929980/

almost every reply to him is 1pbtid and in the first thread you can see him samefag to offer himself money, so (((Lambright))) could say "n-no I don't need it thanks" while dropping the youtube link with the donation links

-do not give him money
-do not give him views

this has been a public service announcement
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>>544099461
That's a pretty good trick. How'd we set ourselves up like that? Now more fool me once. If we didn't catch it then, there isn't another chance.
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>>544100730
nobody should report this post for advertising, btw, since that would really make this jewish faggot seethe
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everyone on /pol/ loves jews trying to take advantage of us, right? right
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>>544100791
Should've asked help for the poor widows son or at least the sign for distress.
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>>544100716
>How'd we set ourselves up like that?
everybody knows the military industrial complex, but what is even bigger is the medical industrial complex. so before 1970 (wild how much changed in the wake of the JFK assassination) the number one financial burden associated with sickness was loss of wages. Medicare changed that. just like the military, the medical industrial complex had a blank paycheck. at first this drove innovation, we got MRI machines, PET scans, new drugs, better surgeries, pacemakers, all kinds of high tech high cost stuff. then, what happened is what happened to everything else in the 1970s, investors started buying the hospitals from the churches and turning them into profit machines rather than trying to heal the sick. today we are at the end of that system. what happened to this country is we allowed people to earn income by speculating in markets. the speculators found a way to own pretty much everything and now all of our institutions are corrupt, gone because they were sold off (manufacturing), or set up to make money rather than be effective at their purpose (keep people sick so they keep paying you money).

basically, kill all investment bankers, make the stock market illegal, treat retirement like an insurance policy that is run by the state. all of the stuff Hitler did. read the 25 points of the NSDAP if you want to learn what they actually did.
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>>544098909

Not cancer what I see as risk but accidental matches could trigger uncontrolled cell death. A question of proper design.
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>>544098918
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>>544097801
I'll give the papers a read, anon, but I'm preemptively calling bullshit.

cGAS-STING already does what you describe, and it avoids killing the host cell where possible. Unless a virus specifically targets that pathway, I don't see why this would be preferred to just promoting the IFN/STING pathways in people who are known to have been exposed/infected.

- dsRNA _IS_ used by healthy cells for gene translation (promoter and suppressor siRNA binding, hairpins, stress granule formation, etc.). The first two are transient, granted, but stress granules/P-bodies aren't.
- TAT can get past the PM, sure, but it depends on caveolae formation. It won't be able to enter a viral inclusion body. Instead, once it's inside the cytoplasm, it uses a nuclear localization signal, and it will ALWAYS find dsDNA to bind in the nucleus (and it won't be viral DNA, either).

- this just increases the probability of a cell inducing apoptosis (killing itself), which (especially in the pro-inflammatory stage of infection, or during cellular stress/physical trauma (which is fairly frequent unless you're bedridden)) is already high enough to cause collateral/unnecessary damage
- cells already induce antiviral (and apoptotic) pathways upon dsDNA detection in the cytoplasm, and they're much more specific than this shit (this induces apoptosis anywhere, natural mechanisms detect based on distance from the PM, suppress themselves around a nucleus breach, etc.
- DNA viruses almost exclusively reproduce in inclusion bodies, often in the ER (to avoid those natural detection+defense mechanisms)

TL;DR: probably does more harm than good in actual people, our cells already have a mechanism that does this, and tacking TAT regions on anything that fucks with dsDNA is pantsu-on-head retarded
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>>544097801
DEATH JABBERS FOR GLOBOHOMO
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>>544103737
thank you biologist anon!
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>>544097801
I have also discovered that boiling sulfuric acid will kill viruses, I'll need 200 million dollars for my research but the us government big pharma is stopping me from getting funding
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>>544104536
we keep testing it but i think we need to test it more



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