Best lifts and supplements to increase prefrontal cortex volume and connectivity and decrease default mode network activity? On some days i feel absolutely in tune with the world, performing flawless task execution like a mercenary. On other days i feel like retarded dummy, too much in my head filled with nonsense and unable to focus on anything. It affects lifting sessions too.
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>>76987114
>>76987120
>>76987064Tren 300mg
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>>76987124Mike Israetel says steroids decrease his IQ and cause brain fog.
>>76987127
>>76987131>Mike Israetel says steroids decrease his IQ and cause brain fog."Dr." Mike Israetel takes the wrong kinds of steroids for brainmaxxing, shrimple as.>https://scholar.google.com/scholar?q=ecdysterone+alzheimer%27s
>>76987145ecdysterone can't cure alzheimer, wtf if this
>>76987064>Functional near-infrared spectroscopy methods found that moderate intensity, acute aerobic exercise enhances activation of the DLPFC and was associated with improved Stroop test resultshttps://openprairie.sdstate.edu/cgi/viewcontent.cgi?article=1021&context=biomicro_plan-b
>>76987064I just today found out that green tea essentially suppresses the PFC. Flow state is the enemy, remember that.
>>76987064Your stated goal and description are polar opposites. DMN is partly prefrontal, the state you're describing isn't.
>>76987217>ecdysterone can't cure alzheimer, wtf if thisNo it probably can't, but a clanker overview of the preclinical research on it does make it look like at least a somewhat effective treatment.
>>76987064look into neurogenesis
>>76987420>green tea essentially suppresses the PFC.How?
>>76987064>Sertraline modulates hippocampal plasticity via sigma 1 receptors, cellular stress and neurosteroidsSertraline enhanced brain function like no other anti-depressant. https://www.nature.com/articles/s41398-024-03185-3
>>76988941>Among the three SSRIs we have studied to date, only sertraline acutely inhibits LTP induction and it does so by unique mechanisms involving S1Rs, NMDARs, cellular stress and neurosteroids. While acute adverse effects on CA1 LTP could cause cognitive dysfunction [77, 78], partial NMDAR inhibition and neurosteroid generation may also contribute to therapeutic effects of the drug.Kek.
>>76987447Poor reading comprehension, I said "decrease default mode network activity", not how to decrease activity of it's separate parts.
>>76987064Cobenfy
>>76989812
>>76987064You're in luck, this is literally my job and specialization so listen closely.>increase prefrontal cortex volumeDon't bother trying to do this specifically.>increase prefrontal connectivityIs nice, but not really something that should be a particular aim>decrease default mode network activityNot something you should aim for. Forget about trying to "improve" your brain or "hack" your brain, it's all garbage. The brain already knows perfectly well what it's doing, it doesn't need improving upon. When you look at certain brain areas, the "cosmic speed limits" of maximum processing have already been achieved. They have been achieved so long ago, we share the architecture of those brain areas with mammals we last shared a common ancestor with like 95 million years ago.The problem is that this brain of ours is adapted to circumstances in the wild our ancestors had to live in, 50,000 years ago, 100,000 years ago, 1,000,000 years ago, and so on. It "expects" certain challenges to happen, and it depends on the associated stimuli to regulate itself. The neurotransmitters and hormones you need to focus, they themselves depend on you focusing on things to be made and released. So if you break that self-maintaining cycle, and you need to focus, you don't have the neurotransmitters to do it, and you won't get them because they need you to focus to keep the "factory" running that makes them.Again, these self-regulatory systems are far, far, far more advanced than what you believe, what most people believe. It's basically bio-technology. It's not about hacking it or changing it in specific ways, it's about just getting to work as intended.
>>76990084>this is literally my job and specializationWhat job is this?
>>76987064>>76990084You're also in luck because two of the most important "cycles" that are involved in exercise and cognition in men, are of the "self-sustaining" type (acetylcholine and testosterone), while dopamine is kind of like it, but also different.You need testosterone to pursue sex. You need to pursue sex to make testosterone. You need testosterone to endure adversity. You need to endure adversity to make testosterone. You need testosterone to grow muscle mass. You need sufficient muscle mass to make testosterone. In nature this is never a problem because either you're doing all the things it takes to survive, or you're not and you're dead. So these kinds of mechanisms completely fail if they are disrupted (like in modern society). Again, you don't need to hack anything, target anything, "improve" anything, just get it to work as intended. With testosterone and acetylcholine it's very simple, YOU need to start the cycle. You can take supplements or eat foods that provide building blocks for them or stimulate their production, but in the long-term it accomplishes nothing if you don't engage in the BEHAVIOURS they are associated with. Behaviour is the real supplement for both testosterone and acetylcholine. Look up what testosterone does. Actually, I'll help you out: https://pubmed.ncbi.nlm.nih.gov/2263798/ This article reviews a bunch of studies that involve testosterone injections in males. Young males that are healthy, young males that are deficient, adults that are healthy, adults that are deficient, elderly men that are healthy, elderly men that are deficient. You take all the averages from all those studies in terms of how the behaviour of these men changes, healthy or unhealthy, and you start to get a pretty good idea of what testosterone does. Just do a bit of research, stick to reliable material that's used in university courses and shit, don't believe a thing you read on different influencer blogs and webpages and shit.
THIS IS NOT A PASTA
>>76990091Using research on the genetics and neuroscience of ADHD and autism to shape governmental, educational and work-related policy regarding their integration in society. My specializations are evolutionary neuroscience, specifically the architecture of cells in the human visual area and the way they go about processing data from the retinae (which works kind of like one of those old TV screens), and behavioural endcrinology, specifically human mate selection throughout our evolutionary past, and how it has shaped the layout of the male and female nervous systems.>>76987064>>76990084>>76990107Anyway, moving on to focus/acetylcholine: completely change how you think about them. What you commonly think of as focus, is not what you are doing with your consciousness at all. With your consciousness, all you're doing is TRYING to focus. The focusing is done by your brain. You can assume the ability is always there (unless you're born after like 2008, gen alpha is pretty fucked). What your responsibility is, is just TRYING to focus. Whether you are able to or not. It's about directing your mind and steering it in the direction you need it to. If focus is a flashlight, you are not the one MAKING the light, you are just pointing the flashlight. Focus is heavily related to testosterone, since both are tied into effort, and dopamine as well. Dopamine is a very long story I won't get into, but just understand that dopamine isn't happiness or joy. Dopamine is desire. You want something. You accomplish that goal, then dopamine causes the release of endorphins, and they are what feels good. Heroin is so horribly addictive, because it basically lets you inject an external form of endorphins. It's like winning an Oscar every time you do. If you want to have energy, drive, motivation, getting shit done, the key is getting used to effort, even learning how to enjoy it.
>>76987064>>76990084>>76990107>>76990119And this brings me to the conclusion, which is what your focus should be on the anterior cingulate cortex (ACC). THIS is the REAL "hub" that controls how much of your cognition, focus and energy you can use, not your prefrontal cortex.Imagine you have a desire, an impulse, an idea, a plan, just any signal sent from your pre-frontal cortex (PFC) to other areas of the brain, or through your nervous system in your body. The ACC is like a "gate" that decides whether those signals actually reach their destination or not. You can want something like the dickens, but if your ACC says no, it's no. Obviously how it works is a lot more complex than I'm about to explain, but you can basically assume that what "fuels" the ACC is effort. You can grow is basically just like a muscle, and just like a muscle needs weight, the ACC needs effort. The more effort you expend in your life, the more signals the ACC lets through.You can see how this problem ties into the testosterone/acetylcholine cycle stuff. You break the cycle, and it becomes very difficult to get back into it. If your ACC is shot, and you need to start expending effort to cultivate it, it's going to be very difficult because your fucking ACC is shot, so you're going to have trouble doing what you want and need. The best way to "grow" your ACC with exercise is simply adversity. Pain, pain, pain. All kinds of pain you have to endure (the ones where you don't risk injury). Muscle burn, pain on the skin of your hands from climbing, pain in your abs from planks, that sort of thing. You learn to endure those things, your ACC will grow in density, connect to more areas of the brain and become more energy-efficient. You get used to it enough, and you will genuinely learn to enjoy that feeling.
>>76990084>>76990107>>76990119>>76990128I express utmost gratitude for your effort.
>>76987064>>76990084>>76990107>>76990119>>76990128And finally, a type of "button" you can press in your body to make sure your brain is able to develop the most (plasticity, as it's called) is lactate. When your muscles break down glucose during exercise, lactate is made as a by-product and stored for two reasons. One is that it can be used later, it can be broken down as well as a source of fuel. The other is that the act of producing ATP (the source of energy for your cells) releases hydrogen ions. Hydrogen ions are acidic, so when your cells are pumping out ATP while you're exercising, the acidity of your muscles will increase. Lactate acts as a buffer against the acidity, so it's like a win-win for your muscles to keep it around when glucose is consumed. Your muscles can only hold a certain amount of lactate however, and as you burn more glucose and accumulate more hydrogen ions, at one point the lactate "spills out" into your bloodstream. This is where you start to feel crazy muscle burn because it doesn't optimally buffer against hydrogen ion acidity anymore.Try to sustain that feeling as long as you can, because lactate in the bloodstream triggers a whole cascade of reactions that cause the brain to produce and release BDNF (basically human growth hormone for the brain). As you can see, this is a double win because enduring the muscle burn stimulates the ACC, and it increased BDNF (which does a LOT more good things in your brain than just help the ACC develop). Finally, do a 24-hour fast at least once a week, once every 2 weeks. Your body starts cleaning up garbage because it's a drain on limited resources, and a lot of these systems "reset" to their "baseline". Also you produce a shitload of growth hormone which is great for muscle gains.
>>76990128NTA. I hypothesize what could also help develop the ACC would be trying to control every movement of your body, including facial expressions, and it's positioning, since ACC is involved in conflict monitoring. Basically eliminate all twitching, scratching, jerking, always keep good posture, direct your gaze in correct direction.
>>76990084name of book on this pic?
>>76987064>to increase prefrontal cortex volumeThis is notoriously hard to do via drugs/supplements, and messing with something so important so directly sounds like something to only do if you're really careful. There are some decent nootropics for boosting e.g. hippocampal growth though without big risk.My two cents for brain:>prioritize foods with polyphenols and "good fats"; foods with both, like olive oil and dark choccy, are top notch>Seafood is your friend; it has DHA which makes up a huge chunk of a healthy brain (sea animals are the best source but sea plants are still okay), plus some nutrients like iodine that are hard to get enough of otherwise>Digestion diverts blood flow to the gut and away from the brain. Sticking to a few big meals instead of spread-out snacks means more time with superior brain oxygenation.>Change your routine in small ways constantly, esp. workouts; do things in a new order or start on the other side, for instance. This activates the brain where it wouldn't otherwise; everyone's a winner.>Add challenges to balance, spacial awareness, and other dimensions where you can do it safely>read lots of books and be at least a little bit socialenjoy your brain gains
>>76990463Putting it all together, I suspect the best fitness activities for your brain involve all of>interpersonal aspect>spacial awareness>ample room for novelty>requirement of actual strength and not purely cardioIf not for that last one I'd say sports like tennis any volleyball are optimal. US football/rugby would be great if not for the great chance of brain injury. Maybe water polo?Cardio is fine, and doing at least a little bit to cover that base is wise, but I have a feeling you hit diminishing returns pretty quick compared to richer weight or calisthenics routines. On that note I wish I could weigh in with practical tips like>X lift is better for brain than Y lift because ___Hopefully others can offer their insight on that
>>76987064pic related and psilocybin basically did a reboot on my personalityI am a different guy from years ago
>>76990524Could you elaborate on what exactly had you done and what changed?
>>76990524>Ayahuasca is suspected of triggering psychosis and schizophrenia in people with a predisposition to the condition
>>76990128>The best way to "grow" your ACC with exercise is simply adversity. Pain, pain, pain. All kinds of pain you have to endure (the ones where you don't risk injury)Cold shower bros were right...
>cat
>>76990636Wtf is this?
>>76990530>on what exactly had you doneat 26 I went on the deep end with DMT and beta-carboline compounds like harmine, harmaline, tetrahydroharmine. Did it alone in my own apartment in a period of my life where I could experiment without bothering anyone>what changedpeople commented that I somehow changed and I became way more relaxed/chill/Zen/calm, different words for the same thing, and somehow pinpointed that period when I was experimenting but they couldn't figure out what I did to me and they literally asked me what did I do to meAll I can say is that it made me less neurotic, more assertive. More grounded and less impressed by magical thinking or OCD/anxious behavior in me or others. You will say I sound like a redditor but it gets rid of depression. That whiny bitch part of your brain that love self-pity and can't stop ruminating about what will happen or how you will screw it up?? it basically goes away like a bad tooth. I still have bad days, feel melancholic sometimes, but you deal with it. way betterDidn't make me smarter or more focused like OP wants (seems like he wants to take meth in the end). I was already high IQ and taking the psychs didn't make me worse - I learned a third language as requirement for my work, picked up music as main hobby, started lifting+running. >>76990558exactly, the ayahuasca trips are basically half-psychosis and the most schizophrenic stuff you can ever live, people will ruin themselves if they are not careful with it. Some people will certainly fry themselves permanently with this. shrooms are the whimsy, more laid back cousin of ayahuasca, can't find a flaw to them 9.5/10 the perfect drug. Definitely impact your creativity and metaphorical thinking in a good waypic related might interest OPhttps://pmc.ncbi.nlm.nih.gov/articles/PMC10032309/>>76990629>long-term ayahuasca use has led to increased thickness of the ACC and decreased thickness of the PCC (a key DMN node).
>>76990664>DMT and beta-carboline compounds like harmine, harmaline, tetrahydroharmine. Did it alone in my own apartment in a period of my life where I could experiment without bothering anyoneHow can someone replicate your experiment? What exact compounds and dosages had you used, if still can recall it? What was your mental state/content at the time of doing the experiment? >Some people will certainly fry themselves permanently with this.I suspect it happens to those low-IQ hippies expecting divine revelation or some other "spiritual experience" instead of using it as brain enhancement tool. >somehow pinpointed that period when I was experimenting but they couldn't figure out what I did to me and they literally asked me what did I do to meThat's funny. What had you answered them? "Well, let's just say..."
>>76987114>prefromtal cortex>morality>Why are they like this?/fit bros, did we just answer the jew question?Was it pathological prefrontal cortex development the whole time?
>>76990717Actually it's responsible for morality only if you're a neurotypical and not a psychopath (NGMI), then your limbic system basically hijacks it to elicit strong negative emotions when considering actions leading to displeasement of others.
>>76990729Ok, but how about the notorious lack of creativity the jews are known for?That also points to malformed or underdeveloped prefrontal cortex
>>76990746I don't know if creativity is a real trait that can be measured and if it's beneficial. If we measure it by capacity to do technological advancement then there are many jewish scientists.
>>76990758That is simply not true.Invention is one of the defining characteristics of higher man.Art, culture and technology require invention.There are exceedingly few novel inventions attributed to jewish scientists.They are notorious for derivative works based on the inventions of others.They are also notorious for lack of contribution to any arts.It is indeed measurable, beneficial and desirable
>>76990758Ok, but how about fear regulation?Jews are the most paranoid people in the world.This also points to malformation or underdevelopment of the prefrontal cortex
>>76990764>>76990746are you kidding? jews are celebrated musicians, actors, and filmmakers. they've got different brains and so their artistic pursuits are also different. you should see what the crazy jewish porn wizards i've been studying are coming up with. it's 'creative' to say the least. you might argue that they can't create anything beautiful but perhaps through their eyes it is. especially if it leads to the destruction of others- a beautiful bit of propaganda, a beautiful bomb.
>>76990769>This also points to malformation or underdevelopment of the prefrontal cortexOr perhaps hyperactive amygdala.
>>76990702>What exact compounds and dosages had you usedbeen about 2-3 years since I used it last time, I can't remember at this pointcompounds - extracted the DMT myself from mimosa hostilis. The harmalas - either tea from 2.5 grams of peganum harmala, boiled caapi leaves, but in the end just got the pure compounds - 150-200 mg harmine, 150-200 mg harmaline. Harmaline way more punishing on the body, but longer acting. tetrahydroharmine is a whole thing in itself. I would need an hour or two to type what I tried. Too many details (some of them important), it would be redundant to name them here. Even made sublingual DMT to work and it was actually one of the most impressive and beautiful experiences - (full 3D visions, seeing a literal Goddess) Just go on DMT-nexus and enjoy the ride and rabbithole. It is pretty much one of the most extreme experiences you can have as a human>What had you answered them?obviously I couldn't spill the beans to anyone, I work as a doctor and also uni teacher
>>76989814All sorts of random chemicals upregulate BDNF without 5-HT2A agonism. Not that 5-HT2A agonists are necessarily bad, but they are unnecessary to just induce BDNF. Here is a review on a bunch of BDNF inducers: https://www.mdpi.com/2076-3425/15/3/252>>76990084>Forget about trying to "improve" your brain or "hack" your brain, it's all garbage.A whole lot of normie meme supplement "hacks" or "impr00vements" are at least a little legit from le Ashy-Ganja to le methy-lean bl00 (each at low doses and not for too long chronically) but it does take significant biochem expertise to sort through the research well enough to take hundreds of things without poisoning yourself.
>>76990140Good shit, I have some more stuff to read and other things I am going to work on now. Thanks for the posts.
>>76991201>https://www.mdpi.com/2076-3425/15/3/252Good read.
>>76991201>methy-lean bl00Isn't it basically a MAOI like any other?
>>76990746>>76990764Lol an amazing cope. Wonder what flavor of a third world rat you are to think you can even talk about Jews who are far superior and more creative than anything your slave "people" will ever come up with, little pathetic shitskin.Now go pray to your Jewish god and masters, subhuman loser.
>>76991996rare kike appearance
>>76992034Ashkenazi jews are superior type of whites.
>>76992034Keep barking little dog, at least you know you are factually an inferior subspecies
>>76991201Bro, do you know if there are any way to permanently remove accumulated AGEs from the body, according to current research? Haven't looked into this topic much.
>>76990785>jews express the creativity they definitely have only through pornographyfascinating
>>76990794>Or perhaps hyperactive amygdalaThen how do you explain the other phenomena that indicate a malformed prefrontal cortex in jews?
>>76991996>jews are creativeName one major non-derivative novel invention coming from a jewCan you name any substantive contributions to the arts? (I am not talking about degen low brow ape shit)
>>76992034>rarekekThis place is mostly jew-bots and idf now
>>76992086>Name one major non-derivative novel invention coming from a jewReligion of christcucks and shitskins.
>>76992086The Bible.Now your turn. Name something your people have contributed, let's see what the shitskin with the big mouth has to offer except envy of his betters.
>>76987064Thread derailed by 1 guy who lets jews live rent-free in his head KEK.
I am going to do a full investigation into this topic. My hypothesis based on historical and current stereotypical behaviours of jews is that they have a malformed prefrontal cortex leading to a range of psychological pathologies, such as lack of morality, difficulty regulating emotions, paranoia, extreme aversion to physical discomfort and low creative potential.I plan to aggregate objective data from mris and brains scans to investigate this hypothesis.Will report back after the investigation is complete.I further hypothesize we have found the answer to the millenia old jewish question.
>>76992091That's right shitskin. You got owned in the battlefield and you will get owned on 4chan, except here you can't run to hide behind your women and children like the cowardly "man" that you are lmao
>>76992095>Bible is le creative!The bible is completely derivative.judaism borrowed from many different religionsit did not create a new onetry again
>>76992101Lol nice projection from a buckbroken shitskin. I'm sure a brown subhuman like you is a role model of morality and developed prefrontal cortex
>>76992103>posted nothing his people contributedlol.It's always the most inferior, pathetic third worlders who will critique other people's works, yet have nothing to show for themselves. Keep seething, inferior brown rat
>>76992101If they would have inferior brains they wouldn't have been overrepresented in top positions of society and have access to so much of economical and political resources. They clearly do something right.
>>76990140Growth hormone doesn't increase muscle mass in healthy adults, especially not in a fasted state with no nutrients available.Growth hormone goes up during a fast because it's a stress response to liberate fatty acids for emergency energy. The body becomes GH resistant during a fast and igf-1 drops to halt growth processes when no nutrition is available, in order to conserve energy during starvation.
>>76992274>Growth hormone doesn't increase muscle mass in healthy adultsSearch Growth Hormone/IGF axis>Growth hormone goes up during a fast because it's a stress response to liberate fatty acids for emergency energy.And to preserve muscle mass. >GH resistantNo such thing.
>>76992274>Growth hormone doesn't increase muscle mass in healthy adultsCertainly seems to: 44 articles describing 27 study samples met inclusion criteria; 303 participants received growth hormone, representing 13.3 person-years of treatment. Participants were young (mean age, 27 years [SD, 3]), lean (mean body mass index, 24 kg/m2 [SD, 2]), and physically fit (mean maximum oxygen uptake, 51 mL/kg of body weight per minute [SD, 8]). Growth hormone dosage (mean, 36 µg/kg per day [SD, 21]) and treatment duration (mean, 20 days [SD, 18] for studies giving growth hormone for >1 day) varied. Lean body mass increased in growth hormone recipients compared with participants who did not receive growth hormone (increase, 2.1 kg [95% CI, 1.3 to 2.9 kg]), but strength and exercise capacity did not seem to improve.>especially not in a fasted state with no nutrients availableNo, this happens after refeeding. Elevated levels of growth hormone during fasting increase activity in the GH/IGF-1 axis. Even though GH levels drop after refeeding, activity in the GH/IGF-1 axis remains elevated between 8 and 16 hours depending on the individual.>Growth hormone goes up during a fast because it's a stress responseBased on observed mechanisms, the opposite seems to be the case. GH is associated with tissue mobilization and preservation, during and after fasting. Its elevation is not associated with any transient endocrine mechanisms. Lipolysis during fasting is not controlled by GH, it is controlled through GH. Elevation of GH during fasting per se does not trigger lipolysis, rather it seems that pulses of high GH concentrations trigger it, controlled by another endocrine mechanism (which is not yet known). >The body becomes GH resistant during a fast and igf-1 drops to halt growth processes when no nutrition is available"Growth" hormone is kind of a misnomer, since the actual function of the hormone seems to be tissue maintenance/mobilization.
>>76992274>>76992363Some reading material: https://www.acpjournals.org/doi/10.7326/0003-4819-148-10-200805200-00215https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2024.1401780/fullhttps://link.springer.com/article/10.1186/s40842-022-00137-yhttps://www.mdpi.com/2072-6643/17/13/2061https://link.springer.com/article/10.1007/s44361-025-00007-z
>>76990136>EffortHa. But this stuff is kind of the bread and butter of what I'm currently doing so it's at my fingertips already. Every child with ADHD should do harsh exercise, every child with autism should be taught to do some form of yoga/tai chi/kung fu body coordination. I'm really trying to get this message through to people who don't give any remote fucks and have no clue about this shit. So, it's relatively easy to transmit this information to /fit/izens who care about these mechanisms, and at least have some knowledge of their own about these things.>>76990217Yeah, another way of looking at the ACC is that, instead of it being a gateway, you can see it as a "muscle" that pushes signals through your nervous system. If the "muscle" is weak, the signals are weak, if the "muscle" is strong, more of your mental impulses are put into action (whether that's mental in regards to mobilization of other brain areas, or physical through mobilization of the body). This is why I think autistic kids should do kung fu/tai chi, because practitioners of Chinese martial arts have figured this out a very long time ago. Their regiments involving body conditioning, highly repetitive intense exercise, highly coordinated and controlled movements, synchronization between mind, body and breath are all so specific to how the ACC coordinates neural signals that it can't be a coincidence. Obviously they would have had no idea about the ACC itself, but they certainly figured out which buttons to push in the brain and body through exercise to cultivate the function it fulfills. That function is heavily lacking in people with autism (but not intrinsically, mostly due to modern society).>>76990360https://global.oup.com/academic/product/an-introduction-to-behavioral-endocrinology-sixth-edition-9780197542750Really, really good book.
>>76992392>Every child with ADHD should do harsh exerciseAnd then you've got people like me: ADHD and exercise-induced asthma. Harsh exercise felt like I was asphyxiating.
>>76992487fuck life
>>76992392>https://global.oup.com/academic/product/an-introduction-to-behavioral-endocrinology-sixth-edition-9780197542750Thanks. Do you have any neuroscience books recommendations?
>>76992487ADHD drugs are always an option.
>>76991976>Isn't it basically a MAOI like any other?It does a fair amount of other stuff too but the MAOI property is why you can overdose on dozens of milligrams from eating ripe fruit.>>76992077>permanently remove accumulated AGEs from the bodyPicrel; induction of endogenous detoxification plus pharmacological degradation of their receptors.
bump
>>76990664
>>76992944
>>76992392Interesting thread, thank you for your input.
>>76992105My people have invented virtually everything in modern society.>>76992121>low IQ attempt at reading comprehensionMy hypothesis is not about IQ; that is another discussion entirely.My hypothesis is that negative jewish stereotypes are the result of a statistically much higher rate of malformed prefrontal cortex in jews.>Unregulated paranoid emotional outbursts followed by misstatement of my hypothesisSo far, the reactions of jews in this thread only serve to bolster my assertion that jews display many symptoms associated with an underdeveloped, malformed or otherwise dysfunctional prefrontal cortex.The symptoms all fit.It would be groundbreaking if we can prove the jewish question is not a matter of religion, teaching, discrimination etc, but rather due to an objectively provable genetic and biological issue in a large portion of the jewish population.Once again, 4chan is at on the cutting edge of scientific inquiry
>>76993495>My hypothesis is that negative jewish stereotypes are the result of a statistically much higher rate of malformed prefrontal cortex in jews.Or it's just ressentiment. You can't really tell until you look at the data.
Man, I completely forgot the name of that guy and his "blog" or whatever. The guy that talks about health, seed oils, etc. Can anybody help me? He's fairly famous on here.
>>76993528>The guy that talks about health, seed oils, etc.100 different channels fall under this description. Maybe you mean High Intensity Health channel.
>>76993540I realize that, my brain will remember eventually. I'm pretty sure the guy is dead I just can't remember his name and it's killing me. He had extremely long write ups on his website about a multitude of different topics my memory is just failing me atm.
>>76993552Why do you want to find him?
>>76993552Now that you told he is dead i think you mean Ray Peat.
>>76993565Yes, thank you.
>>76992363Lean mass is not the same as muscle mass. That's why their strength didn't increase.https://pmc.ncbi.nlm.nih.gov/articles/instance/1724606/pdf/v037p00100.pdf
>>76994035Growth hormone is a stress and feminine hormone. Women produce twice as much growth hormone than men do.
>>76987064Hard redpill to swallow:Math mogs literally everything else.>it carryovers somehow>increases focus without neglecting short term memory like lecture>increase in mental clarity>emotions affect working memory,so the stronger working memory is the less emotional you'll feel>There's as much information in a single equation as 150 pages of a book, so trying to understand math deeply will level up your brain>once you know math, youll be able to hover over any discipline or college career you want
>>76987420I bet all caffeine does it. It triggers your fight/flight to make you more alert.
>>76994069From my experience, coding does NOT do this. At least not nearly in the same way. Especially not with the vibe coding shit these days. Getting the computer to do everything literally atrophies your brain.
>>76994093Most coding doesn't, unless your purely working in C and solving difficult problems. Math is really a different beast.>t. failed/failing coder. I didn't even enter this shit for the money, but neither am I passionate about it. Very fucked.
>>76987064All you need
>>76994125All you "need" some basic bitch essential nutrients. But what you "need" is the tip of the iceberg on advanced supplementation, and just like half my stack mogs your copypasta...>Vitamin A 1.5mg>Thiamin 1mg>Riboflavin 1mg>Niacin 15mg>P5P 30mg>Methylfolate 1mg>Methylcobalamin 100mcg>NMN 300mg>Biotin 500mcg>Pantothenic Acid 5mg>Vitamin C 500mg>Vitamin D 3,000IU>Vitamin E 15mg>Menaquinone-7 100mcg>Iodine 800mcg>Magnesium glycinate 200mg>Zinc 15mg chelated>Copper 3mg>Iron 8mg>Manganese 4mg>Chromium 50mcg>Vanadium 4mg (dosed once a week)>Molybdenum 50mcg>Selenium 200mcg>Boron 6mg>Red ginseng extract 600mg>Berberine 500mg>Fisetin 500mg>Meclizine 25mg>Bromelain 500mg>Turmeric 1g (30 days on, 15 off)>Rhodiola rosea 500mg>Elderberry extract 1g>Ashwagandha 300mg (30 days on 15 off)>Astaxanthin 20mg>Zeaxanthin 2mg>Luteolin 100mg>Banaba extract 60mg>PQQ 40mg>Alpha lipoic acid 600mg>NAC 1,200mg>Glycine 3g>Betaine 2g>Arginine 1g>Sulphoraphane 400mcg>Alpha GPC 650mg>Citicoline 300mg>Phosphatidylserine 80mg>Ubiquinol 100mg>Uridine monophosphate 60mg>Methylene blue 5mg>HMB 3g>Ecdysterone 600mg>Cordyceps mushrooms 1g>Chokeberry extract 3g>Blackcurrant extract 3g>Acai extract 3g>Collagen peptides 15g>Extra virgin olive oil 15g
Thoughts on noopept and/or racetams?
>>76994093Im talking about good ol normal math doeI dont know about programming
>>76994218>VanadiumYou're out of your mind.
>>76987064>Best lifts and supplements to increase prefrontal cortex volume and connectivity and decrease default mode network activity?
>>76987064is nobody really going to bring up how the dog brain looks like a guy with a joocy back doing a dogeza bow?
>>76994324Not potent enough to notice a difference.
>>76994218>LuteolinInteresting stuff. But bioavailablity is low. >While total luteolin (free + bound) absorption might seem decent (around 53.9%), the actual free luteolin reaching the bloodstream is much lower (around 17.5%), with most being converted into inactive glucuronide or sulfate metabolites. Strategies like nanoformulations, lipid carriers, and microemulsions are being developed to improve its absorption and efficacy.
>>76994218Why meclizine?
>>76994061Dude, you desperately need to learn just basic endocrinology. There is no such thing as a "feminine" or "masculine" hormone. They are mediators. What shapes "feminine" and "masculine" behaviour and traits is the layout of the nervous system. Hormones work with whatever they got, they work with the mechanisms they can interact with. It's the mechanism that decides what the hormone does, not the hormone itself. Did you know that in human males, it's estrogen that shapes the brain? Oh yes. Testosterone is required for brain development, but in order to achieve this it's converted into estrogen locally and that estrogen interacts with estrogen receptors to shape male brain physiology. The same process is also responsible for initiating sperm production during puberty. You don't seem to be familiar with endocrinology so let me explain pic related. P450arom is aromatase, the enzyme that converts testosterone into estradiol. ERα and ERβ are estrogen receptors. As you can see ERβ receptors are ubiquitous during male development (ubiquitous means they are everywhere). Leydig cells are the cells in male testes responsible for producing testosterone. As you can see, ERα receptors are not just a crucial mechanism, they are THE mechanism for initiating testosterone elevations and spermatogenesis in developing young males. There is nothing "feminine" about estrogen, nor growth hormone.Did you also know that in animal species where the female more aggressively pursues sex than the male, the females produce more testosterone than the males? Testosterone doesn't stop them from being the egg-bearing gender. There is nothing "male" about testosterone that makes them anything other than a female.This is incredibly basic stuff that even first-year students of psychology get exposed to in "child development" classes or endocrinology electives.
>>76987064One of techniques of decreasing DMN activity is to focus on situational awareness (which is task-positive) instead of whatever comes to mind.
>>76987064Will taking phenylpiracetam fuck me up in yhe long run? It’s relatively affordable where i am and there’s a bit of literature on it, but I worry taking a stimulant to be productive would set a bad precedent for my brain. I’m autistic in grad school with attention issues, so I probably need this more than my normie peers who seem to breeze through courses without working half as hard as I do. Still, like I said, I worry about being dependent on this thing in the future to perform well (especially given the major shortages a few years ago) and the potential impacts of stimulants on the brain. Apparently it’s no worse than extended release caffeine but I worry easily
>>76995009>autisticYou’d probably benefit
>>76995009It's not as addictive as amphetamine derivatives, so you can try.
>>76987064https://en.wikipedia.org/wiki/Coluracetam#Mechanism_of_action>Coluracetam enhances high-affinity choline uptake (HACU), which is the rate-limiting step of acetylcholine (ACh) synthesis. Studies have shown coluracetam to improve learning impairment on a single oral dose given to rats which have been exposed to cholinergic neurotoxins. Subsequent studies have shown that it may induce long-lasting procognitive effects in cholinergic neurotoxin-treated rats by changing the choline transporter regulation system.
>>76995050
>>76995097
>>76995105
>>76987064After researching this topic for some time i reached the conclusion that before trying to improve and boost your brain in any way first you need to lower your emotionality and emotional reactivity to stimulus (especially abstract stimulus) to 0. Otherwise you will fry your brain.
>>76994218Why no pregnenolone?
>>76994650Yeah you can stfu tranny. Thinking in black and white is nigger tier behavior. Exceptions are not the rule and I'm not some snail.
>>76995538>thinking in black and white is nigger-tier behavior>proceeds to throw a tantrum about how estrogen is a female hormone and testosterone is a male hormoneLOL. Arrogant AND ignorant is probably the single most obnoxious combination of traits an individual can possess.What exactly is your point, anyway? The other anon took the time out of his day to compose a well thought out, articulate, and informative post. You respond by calling him a stupid nigger. Bravo.
>>76987064Get sleeping pills, lilbro
>>76987064My girlfriend takes this shit and said it's like doing a line of coke. They say it's only for women but I checked on the back and I don't believe their is anything in it designed specifically for women.https://luvenishealth.com/products/memory-support
>>76996068Have you tried it, yourself?
>>76996109Yeah, I took 3 in the morning and I felt alright. I took them for 3 days and on the 3rd I really started to feel different. I felt more alert and able to connect with my body better. When I was doing cleans I felt a greater snap in the bar and it moved faster.I'd give them a try. They have some other stuff to like Detoxers and Inflammatory relief.
>>76993522>it's prefrontal malformation in jews or it's just ressentiment.Why can't it be both, fren?Should thou not resent the cult leader who kills children?Should thou not resent the nigger who runs a child daycare fraud?We already have many large studies that demonstrate jews have much higher rates of a wide array of mental illnesses.We also know that religious fanatics also have an extremely high rate of schizophrenia and shizophrenic-like illness and delusions of grandeur (in this case a delusional messianic-complex that afflicts a whole tribe of people)Is it really that much of a stretch to think the cause of the multi-millennia jewish question could be a simple biological or genetic tendency towards prefrontal cortex problems?As I said, the symptoms all seem to fit and half of the supporting contextual data is already available.
>>76996415>We also know that religious fanatics also have an extremely high rate of schizophreniaInteresting, source?
Why are you guys so into supplements? whats the redpill there? prettyplease?
>>76996436>whats the redpill there?The redpill is that they work. Even basic things like NAC can have major positive effects on your psyche if applied correctly. Normies think they don't work either because they have 0 understanding of biochemistry and fall for actual scams after which they conclude all supplements are useless or because gaslighting themselves into believing all supplements are scam is their way of combating FOMO.
>139 posts of absolute schizophrenia>not a single mention of EPA/DHA megadosingthe absolute state of this fucking board
>>76987064Deep rem sleep and learning and refining skills are the only way to increase brain mass.
>>76996455>just fill your brain with lipids highly prone to oxidation bro
>>76995668But it is nigga. Go give a female testosterone and let's see whether your premise based on an exception holds true. Btw, you throw a tantrum trying to defy nature, I just tell the truth to a stupid nigger. And no matter what you say, I'm right anyway. It's just circles being circles, no point in arguing with a lgbt freak or redditor lmao.
>>76990084>another self important PhD faggot who never tried a drug in his lifeGood job being a good goy with good grades and giving pharma more money but you literally said nothing more than "MUH NEUROTRANSMITTERS"Wait until you learn about brain having its own flora, you literal retardWait until you learn that human gut flora when put in mice actually increases interconnection and ATP gene expression in their brainsYou are nothing more than a parrot that can't think for himself. Plebbit spacing is evident of that
>>76996461you forgot the microplastics, schizo bro
>>76996626But i already had created a thread on microplastics, normie-bro...
>>76996436They work pretty well when done right. Can be easy to fuck up though. Most people really don't need too much either. Keep in mind the average American over 40 is on like 3-5 prescription drugs already. Most doctors will start you on a pill around 30 and add one every 5-10 years. Just heres a pill, bye.
>>76996450My issue isn’t that they work, but that I could become dependent on them to function. Though, that’s more the fault of this gay world that requires you to take stimulants just to produce adequate results. More, more, more, is their slogan, and yet what is limitless growth if not cancer?
>>76996963>but that I could become dependent on them to function.It's called withdrawal. Most supplements don't work like that. With many, when you stop taking them, you just return to baseline. With some, their positive effects last long after you stop.
>>76996709>Keep in mind the average American over 40 is on like 3-5 prescription drugs already.Wtf lol.
>>76996430>thousands of rabbis falsely claim to be messiah>millions claim mystical, magical powers that they cannot ever prove>millions of jews follow them in direct contradiction to all evidenceOr they could all be the real messiah without any trace of mental illness, including the homeless methhead nigger on my street who claims to be the real jewish messiah.
>>76994218>GlycineI came from my buttfuck-nowhere town and got into second largest city on a state-funded/free spot. I grinded my ass off at school, just brutally, and started getting results (at least I began standing out from the pile of rich kids and basic bitches in my group). Then a girl showed up (she studied a related major, we’d bump into each other at the uni sometimes). We dated for almost a year, then moved in together into a rented place out of the dorm (her parents threw her some money, I did side work + both of us had scholarships).One of the professors took me under his wing, started pushing me into all kinds of interesting projects in my field, and under his guidance I began working on a research paper. Everything was going great, BUT NO, FUCK, I needed more! Fuck! Because of all that workload I decided to “boost” myself with meds, started popping glycine. At first it went fine, I even had a breakthrough with studying, my memory improved. But I, dumb fucking idiot, didn’t stop there—I started eating like half a pack a day, and mixing it with massive caffeine doses too.My brain was constantly running, I couldn’t shut off, thousands of thoughts would fly through my head in a second. At night I either didn’t sleep at all, or I’d hover in a lucid dream, so I’d wake up wrecked, like I’d been fucked by 10 niggers.Because of that I first dropped my work, then started blowing off school. One time I locked myself in at the university while on glycine, thinking it was just another lucid dream. My advisor came up to me, asked why I hadn’t been showing up to classes and what the hell was going on with me, and I answered: “Fuck off, you old faggot!” He obviously freaked out, and I bolted. And only by evening did it hit me what I’d done.
>>76997545The next day the dean’s office called; I didn’t pick up. I didn’t even have the balls to come and take my documents. I didn’t apologize either—doesn’t matter, he won’t forgive me. I wouldn’t.I shut down for a few weeks. Lived off my girl; she of course started bitching like, if I’m not studying I need to find a job (I told her, by the way, that I got expelled because of failed classes). Yeah, I need to, agreed. Found some remote gig. Decided to take more glycine so I’d think better, and off it went. Tripping again, insomnia again, got kicked from the job, without pay of course, fucking nothing.My girl started hiding money from me, only gave me food. And I needed to buy glycine, and in the end I stole her earrings and two rings (she rarely wears them, I hoped she wouldn’t notice), pawned them, and with the money got high on glycine again. She noticed the stuff was missing in literally a couple days, threw a scandal and told me to fuck off. I had to move out.I crashed with acquaintances, didn’t have the strength to go back to buttfuck-nowhere to my parents (and admit I’m a piece of shit, which is what they always thought of me). I often slept wherever, even with homeless guys at the station a couple times, lol.The day before yesterday I ran out of money completely. This morning I ran out of glycine. Without those pills my brain started failing, my mental ability began regressing. I dragged myself to a pharmacy on the outskirts, where hobos buy hawthorn tincture. There was this fat freak pharmacist, not much older than me, asked what the fuck I needed. I started begging him to sell me glycine on credit. He told me to fuck off a bunch of times.
>>76997559I left the pharmacy, went around the corner, sat down by the wall—nowhere to go anyway. Half an hour later that freak came out the back door to smoke, saw me, smirked, went back inside. Came out a couple minutes later with a bunch of boxes of glycine, showed them to me and said with a nasty little smile: “Want it? Suck me dry.”Fuck, /fit/. I did it. I sucked that piece of shit for glycine. I’m still shaking when I think about it. Fuck, fuck, fuck! Literally a minute later the bastard came in my mouth and tossed the boxes onto the dirty asphalt, as filthy as my pathetic little soul. With trembling hands I started picking up the pills. While leaving, the fatass turned to me and said: “Why so sad? Dick taste bad?” Then something in me snapped.I screamed like that scream poured out all my pain, all the humiliation and loss, and before I even realized what I was doing, I smashed him in the face so he slumped down the wall, and I added a few kicks to his stomach. I don’t know if I beat him to death or not. He didn’t move. I ran. I ran, shaking with sobs, his blood on the knuckles of my clenched fists and dried sperm on my lips, clutching packs of that cursed, that desired, life-destroying GLYCINE.
>>76997564And then I ran into the professor (the same one I told to fuck off). He slowly looked me over, and I swear, /fit/, he understood everything. I stayed silent. Under his stare—full of contempt and pity at the same time—I felt like the last piece of shit. I froze, and he silently, with disgust on his face, carefully took the pills out of my hands and threw them aside. Then he briefly ordered me: “Come.”I obediently trailed after him. He drove me to his place, locked me in the living room with a mug of tea. He went to the kitchen—he’s been on the phone there for the third hour, talking shit with someone.He hasn’t said another word to me. Neither have I. I don’t know what I’m supposed to say. I insulted a decent person. I lost my girl. I sucked dick like the last whore, and maybe killed a man. Because I was getting high. Fucking glycine. It lures you like a seductive siren, promising to make you smarter, quicker, more successful, to expand the limits of your abilities. And then, in an instant, it takes everything from you.I’d hate it if I could. But I can’t—it's grown into my soul, pushing out me. I dissolved in it. My old life is gone, but it doesn’t matter—I'm gone. There’s only the call of glycine—the eternal, irresistible call.”
>>76997696>it is twice as potent as racemix
>>76987064>Low-Dose Naltrexone: Hype, Hope, or Homerun? | Sean Mackey, M.D., Ph.D.https://www.youtube.com/watch?v=d0S7_H0UdjYhttps://en.wikipedia.org/wiki/NaltrexoneIt's an opioid receptor antagonist. You take it before sleep (because organism produced most of opioids during sleep) in low doses. By the time you wake up your organism upregulated opioid receptors and you become invincible.
>>76997726Imagine what effects on workouts it would have.
>>76997726It even has anti-aging effects.
>>76997726Based.
>>76987064What am i in for?
Rate babies first stack
>>76987064Steady-state cardio has shown the most consistent benefits for brain enhancement.
>>76998838I recommend taking every of this drugs in isolation before combining them to see what actually works and how.
>>76998750I took about 400mg at night to help me sleep for a year straight. I've spent the last 3 months working my way off it and I'm lucky to sleep 3 hours a night right now. It fucking sucks.
>>76987064>Benzydaminehttps://en.wikipedia.org/wiki/Benzydamine>It is hypothesized that it has cannabinoid agonistic activity and this may account for its recreational and hallucinogenic effects. However, it has also been theorized that, based on structural similarity to lysergic acid diethylamide (LSD) and descriptions of its visual hallucinatory effects, benzydamine might be acting as a serotonin 5-HT2A receptor agonist and hence as a serotonergic psychedelic.
>>76997382Prominent religious extremist zionist Leslie Wexner is obviously a schizo.He has talked to many people about his demons
>>76999253>I've spent the last 3 months working my way off it and I'm lucky to sleep 3 hours a night right now. Is it getting better?
>>76999265No it's not. I'm on 100mg down from 400mg and it's not getting any worse but I don't know how long this shit is going to take to be normal again.
>>76999271Gabapentin for dogs sold off-label is very popular in Russia now among zoomers. I ordered 1 pack before they completely ban it off of local amazon, but guess after your report i'll keep it from personal use.
>>76999254
Written reminders are literally what defined a succesful civilization in the past literally 100% of the time.Fucking crazy.I finally decided to stick to my reminders because my new goal is more important than curiosity, and let me tell you, it deloads your mind so much.It allows you to do so much.As your notes and remidners develop, you'll notice you created a mind solely dedicated to organizing your day. Which in turn diminishes cognitive load and allows you to do more, in less time, because you dont have to worry.It's crazy how slept on this is
>>76999429>I finally decided to stick to my reminders because my new goal is more important than curiosity, and let me tell you, it deloads your mind so much.Can you provide some examples of your usage?
>>76999498I get side tracked whenever I focus with somethingIt doesnt seem like much at first but over time it starts loading the mind.Stuff like re-evaluating your working out routine, or study plan,re-evaluating your reminders themselves and such compulsively. This is already a lot of mental load, but if aside your work out routine or study plan isnt written anywhere and you just memorized it, mantaining it in your memory loads it a little more. Remindig yourself to be disciplined also adds mental load. And lets not forget you actually have to work out and lift without getting disoriented, so theres a lot of load in these seemingly mundane things that every body does until they accumulated enough fatigue a decade later and now they're stuck in a burn-out state, so they give up on all their pursuits.Deciding to trust your reminders and do them like they're somebody else's tasks makes you less biased about doing what you're doing and you get less side tracked, which for the mind is also energy efficient.So, no side tracking+not doing all I mentioned+not thinking too much about much will let you realize that you were really over stimulated.It doesnt help I have OCD though.
>>76999429Unless you are autistic and have ADHD, which is when you end up with something like this.
