[a / b / c / d / e / f / g / gif / h / hr / k / m / o / p / r / s / t / u / v / vg / vm / vmg / vr / vrpg / vst / w / wg] [i / ic] [r9k / s4s / vip] [cm / hm / lgbt / y] [3 / aco / adv / an / bant / biz / cgl / ck / co / diy / fa / fit / gd / hc / his / int / jp / lit / mlp / mu / n / news / out / po / pol / pw / qst / sci / soc / sp / tg / toy / trv / tv / vp / vt / wsg / wsr / x / xs] [Settings] [Search] [Mobile] [Home]
Board
Settings Mobile Home
/fit/ - Fitness


Thread archived.
You cannot reply anymore.


[Advertise on 4chan]


File: image.png (363 KB, 1080x1080)
363 KB
363 KB PNG
Anons. did you knew you can permanently and significantly (x2 or more) increase your testosterone level with one-time injection? The drug is called Fulvestrant and it permanently destroys estrogen receptors, your brain thinks you have low estro and sends signals to your balls to produce more testosterone (because male bodies produce estrogen from testosterone).
So unlike TRT you won't have to take it daily, will preserve or even increase your fertility and you won't have any side effects from increased estrogen activity.
>>
>>76989165
Why not just use Clomid or Aromasin(actually boosts T in natties without crashing Estrogen like in roid users) without risking any of that shit with injections?
>>
Crushing your E2 feels horrible and you'll probably get prostate cancer
>>
>>76989165
Don't need it I have 18in biceps natty
>>
>>76989173
Because you have to take clomid daily unlike this one-time injection i propose, and it also contain zuclomiphene which actually exhibits estrogenic activity, lasting in your body way longer then enclomiphene (active component of clomid) - the results is that after you stop taking it you get all negative effects of significantly elevated estrogen. Also it permanently worsens your vision.
>>
>>76989176
Nonsense.
>>
>>76989176
lowering estrogenic activity significantly enhances anti-tumor immunity
>>
File: image.png (314 KB, 1280x720)
314 KB
314 KB PNG
>>76989177
Get it to the next level, bro.
>>
>>76989192
what is the treatment for prostate cancer?
>>
>>76989165
I wonder why Peaters haven't overdosed on it yet considering their aversion to estrogen. Perhaps they're too ignorant or pussy out in the face of actual final solution.
>>
>>76989213
Decreasing androgen activity.
>>
>>76989173
>Aromasin(actually boosts T in natties without crashing Estrogen like in roid users
Can you explain how is it different from all other aromatase inhibitors?
>>
>>76989254
>Can you explain how is it different from all other aromatase inhibitors?

AIs absolutely act differently in men who are not HPTA suppressed, due to the actions of an intact negative feedback loop.

In men not using exogenous androgens it goes like this...take an AI —> estradiol goes down —> pituitary gland recognizes that estradiol is decreasing —> men only have one way to create more estradiol (aromatization) —> pituitary gland increases gonadotropin production in order to create more testosterone —> this testosterone is aromatized into estradiol.

That’s the negative feedback loop at work.

When there is an interruption in this loop (gonadotropin production ceases when we use testosterone), that’s when it becomes very easy to drive estradiol too low. Since we are “shut down”, the pituitary gland is unable to ramp up gonadotropin production in its attempt to create more estradiol via aromatization.

There are numerous studies of men on AI monotherapy in which they used very large doses, but did not achieve anywhere near the suppression of estradiol that we would see in somebody using testosterone as well. We’re talking 1-2mg of Arimidex per day, 2.5mg of Letrozole several times per week, etc. What occurred was a significant increase in testosterone levels, and a moderate decrease in estradiol.

Here are some relevant studies:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3143915/

https://academic.oup.com/jcem/article/88/12/5951/2661508

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795655/

http://press.endocrine.org/doi/10.1210/jcem.85.7.6676

https://www.ncbi.nlm.nih.gov/pubmed/11397902


Copied from LEDDIT. You can check it out for yourself.

>https://www.reddit.com/r/steroids/comments/f0h5am/discussion_taking_aiaromasin_for_low_testosterone/

Basically Aromasin works differently in natties and different in TRT/Roid users.
>>
>>76989257
Interesting, thank you.
>>
>>76989265
Doing blood would be good before you decide to experiment on yourself though.

SHBG
Total and Free T(all though free T is more important)
Estrogen obviously
Prolactin
Cortisol would be good as well
>>
>>76989165
It doesn't work because it doesn't affect estrogen receptors in the brain.
>>
File: image.png (119 KB, 835x562)
119 KB
119 KB PNG
>>76989274
Fine... But Elacestrant does. And it also comes in tablet form. There's also more effective drugs in clinical trials now like Giredestrant and Camizestrant.
>>
>>76989278
If it passes through the liver it's worse for test boost if you're interested in muscle growth because estrogen receptors in the liver are responsible for IGF-1 production. Injections are actually better in this case.
>>
File: image.png (314 KB, 1445x828)
314 KB
314 KB PNG
>>76989257
>Copied from LEDDIT. You can check it out for yourself.
Can you get a screenshot?
Btw are there any possible long-term side effects?
>>
>take too much
>destroy your hormones for life
sounds good OP. Let's see your before and after bloods
>>
>>76989165
if this does what you propose they'd be shilling it endlessly on tv. although it must not have too severe side effects as consequence otherwise also they'd be shilling it endlessly on tv.
>>
>>76989165
>permanently destroy estrogen receptors critical to proper cardiac and neurological function
pass
>>
>>76989165
>Anons. Do you know if you just inject this kiked troon dru....
I denounce the Talmud. Fuck off.
>>
>>76989173
>>76989257
Does that actually work? I feel like I might have elevated Estrogen due to heavy drinking. I get weepy like a fag, sometimes have soft dick. it's honestly horrible.
>>
>>76989895
No shortcuts
>>
>>76990344
bump
>>
>>76989827
>they'd be shilling it endlessly on tv
Why? You can do the same with clomid/nolva. Does it get "shilled" on tv?
>>
>>76989165
From Wikipedia:

Fulvestrant does not cross the blood–brain barrier in animals and may not in humans as well.[21][22][23] Accordingly, no effects of fulvestrant on brain function have been observed in preclinical or clinical research.[22][23] Fulvestrant is highly (99%) bound to plasma proteins.[20][2] It is bound to very low density lipoprotein, low density lipoprotein, and high density lipoprotein, but not to sex hormone-binding globulin.[20]

Low e2 is horrible for you anyway.
>>
>>76992084
>Low e2 is horrible for you anyway.
Yes, but so is high E2. Even slightly above upper range can seriously mess you up.
>>
>>76992087
That's no reason to degrade ERs, especially when it doesn't even raise test lmao
>>
>>76992145
What do you think AIs are for when taking steroids?
>>
>>76992171
I was under the impression we were talking about natties trying to boost their T with a SERM like drug. I guess you could use it alongside AAS, but AI's would be easier to source, with plenty user experiences online which would mean better dosing info and side effect profile knowledge etc.
>>
>>76992145
AI's aren't as agressive on E2 when you're natty. And some men truly have problems with E2, that can't be fixed with diet and lifestyle changes. They just convert too fast.
>>
>>76989165
FAKE NEWS. Two main problems:
>1. fully crashing estro = ACK
>2. estrogen receptors regenerate as part of a process called "receptor turnover" that Fulvestrant just accelerates.
See for example...
>The turnover of estrogen receptor α by the selective estrogen receptor degrader (SERD) fulvestrant is a saturable process that is not required for antagonist efficacy
>https://pmc.ncbi.nlm.nih.gov/articles/PMC3109090/

Might not be a full retard idea if the doses are a lot lower than for titty cancer, but not the ultimate test hack. Receptor degraders can be pretty based, like I used bromelain systemically for RAGE, but it's not really permanent.

>>76990188
I mispronounce the Tell-mood.
>>
>>76989165
This is elite level
>>
bump



[Advertise on 4chan]

Delete Post: [File Only] Style:
[Disable Mobile View / Use Desktop Site]

[Enable Mobile View / Use Mobile Site]

All trademarks and copyrights on this page are owned by their respective parties. Images uploaded are the responsibility of the Poster. Comments are owned by the Poster.