Normies don't know they constantly accumulate permanent damage from>Misfolded proteins>Advanced glycation end-products>Advanced Oxidation Protein Products>Advanced lipoxidation end products>Lipofuscin>Methylglyoxal>Glucosepane>Endogenous uremic‑like toxins>Perfluorooctanoic acid>Mercury selenide>Microplastics>Persistent organic pollutants>Endocrine‑mimicking metallo‑organic complexes>Polycyclic aromatic hydrocarbon adducts >Ultrafine metal‑oxide nanoparticles>Cell-free DNA>Endogenous formaldehyde adductsShall we tell them?
>normiesNot even /fit/ards and biosharters and other people that are knee deep into fitness and health at least relative to the average person care. People cant grasp that microdosing poison accumulates and hits you hard at a certain point and think eating plants laced with pesticides will reverse muh inflammation.
>>77235005>muh normies
>>77235015Only retards care about inflammation when aspirin and montelukast exist. You can literally dose-dependently reduce your inflammation and promote it's resolution with just this 2 drugs.
>>77235005Not researching all that. I'm just gonna assume fasting every so often fixes it all.
>>77235033>I'm just gonna assume fasting every so often fixes it all.Monks would be immortal then.
>>77235028You realize inflammation is just an umbrella term for things that range from DOMS to gout symptoms where your body tries to fix your dietary and habit fuck ups and aspirin just reduces the perceived inflammation if not block the needed reactions. It's no different than blocking your natural cortisol or estrogen production.
>>77235039>aspirin just reduces the perceived inflammation if not block the needed reactions.No, it directly resolves it through generation of aspirin-triggered lipoxins. You're clearly not an alchemist.
>>77235041lipoxins just tell the inflammation to "stop" which is fucking retarded it's literally how your body manages damage and it does so in many ways including your immune system. You wont feel pain or sick anymore but your body will be in worse condition once you get another inflammatory episode. Absolutely moronic. You do you "alchemist" im so over explaining to midwits why blocking your bodys REACTION and SYMPTOMS doesnt solve problems
>>77235046>im so over explainingdoubt it
>>77235046>lipoxins just tell the inflammation to "stop" which is fucking retarded it's literally how your body manages damageNo, lipoxins also stimulate macrophages to clear cellular debris and promote tissue regeneration, it's not retarded and it's not how your body "manages damage" because your body doesn't actually do anything, it's just chaotic chemical reactions. Lipoxins are highly beneficial in many diseases. >Lipoxin and Aspirin-Triggered Lipoxinshttps://scispace.com/pdf/lipoxin-and-aspirin-triggered-lipoxins-4zr9a4xsev.pdf
All of that damage is proven to be reversible.
>>77235068>Could>Might>SuggestsYeah you're a retard, not because of these things but because >He unironically thinks your body is a total black box that doesn't have self repair pathways to release certain molecules or cells and it's just "chaotic chemical reactions"Your bodys lipoxin is good enough, aspirin lipoxin acts the same as "anti inflammatory" drugs that block inflammation resolution
>>77235519>Could>Might>SuggestsIt's the words scientists use. >Your bodys lipoxin is good enough"Good enough" is not the same as optimal. >aspirin lipoxin acts the same as "anti inflammatory" drugs that block inflammation resolutionNo, they directly promote resolution of inflammation through macrophage stimulation, and they are better than natural lipoxins at that.
>>77235510No, it's not. If i'm wrong, show me how to reverse damage from glucosepane, microplastics and mercury selenide, for example.
op won't realize he's the real brainwashed normgoid cattlefaggot until it's too late
>>77235633>It's the words scientists use.And you dont know what they mean. You could be a faggot. Or might be a retard. Information suggests you're low iq.
>>77235039To give you hint they almost exclusively mean chronic inflammatory conditions.
>>77235652>And you dont know what they mean. I know precisely what they mean - they mean there's no certainty in the world of chaos, and the best model of reasoning is probabilistic guessing.I will post more studies regarding beneficial effects of aspirin from my database.
>>77235658
>>77235658>>77235659>A bunch of titlesWho cares you third world midwit
>>77235658Nta that is replying but please continue anon and post your studies. I’m curious of the supporting evidence to chemically reduce inflammation. We do it through hot cold therapy and the like so I don’t see why this would be any different if the studies support it.
>>77235681>Who caresI know you won't read them, i just think it's fun. >you third world midwitI'm 100% white, 195cm/95kg man with outstanding intelligence, narcissism and psychopathy. You made a mistake by trying to argue with me. Perhaps i should post more studies showing that suppressing inflammation is beneficial, this time - with montelukast. >Structural and functional rejuvenation of the aged brain by an approved anti-asthmatic drughttps://www.nature.com/articles/ncomms9466Here we show that a 6-week treatment of young (4 months) and old (20 months) rats with montelukast, a marketed anti-asthmatic drug antagonizing leukotriene receptors, reduces neuroinflammation, elevates hippocampal neurogenesis and improves learning and memory in old animals. By using gene knockdown and knockout approaches, we demonstrate that the effect is mediated through inhibition of the GPR17 receptor. This work illustrates that inhibition of leukotriene receptor signalling might represent a safe and druggable target to restore cognitive functions in old individuals and paves the way for future clinical translation of leukotriene receptor inhibition for the treatment of dementias.>A possible effect of montelukast on neurological aging examined by the use of register datahttps://pmc.ncbi.nlm.nih.gov/articles/PMC8214582/Previous use of montelukast correlated with improved scores on cognitive or neurological functioning (F=2.20, p=0.03 in a multivariate test). A range of other medications were tested with the same algorithm, including drugs acting on the immune system, but none of them correlated with (overall) significantly improved test results. Conclusion: The present data suggest that montelukast may alleviate degenerative neurological changes associated with human aging.
>>77235681>>77235691>Cysteinyl Leukotriene Receptor Antagonists Decrease Cancer Risk in Asthma Patientshttps://www.nature.com/articles/srep23979Totally, 4185 LTRA users and 20925 LTRA non-users were identified. LTRA users had a significantly lower cancer incidence rate than LTRA non-users did. Multivariable Cox regression analyses adjusting for baseline characteristics and comorbidities showed LTRA use was an independent protecting factor (hazard ratio = 0.31 [95% CI: 0.24–0.39]), and cancer risk decreased progressively with higher cumulative dose of LTRAs. In conclusion, this study revealed that the LTRA use decreased cancer risk in a dose-dependent manner in asthma patients.
>>77235005>mineral oil saturated hydrocarbons
>>77235034please walk me through your logic here
>>77236668Monks practice fasting more than any other social class. Yet they still accumulate permanent damage from factors in OP post and die as a result.
>>77236678You haven't explained why they'd be immortal.
>>77236812Because their organs wouldn't degrade. We're talking about biological immortality here.
So I don't care about any of this shit. Someone give me a tldr. What am I supposed to take away
