Why you're not using exemestane to increase your testosterone and decrease estrogen? I started doing it and feel amazing.
>>77245456>edgy teenage deliberately given harmful advice because he thinks its funny threadyawnin all fields
>>77245469You sound low T.
>>77245472Can't say this when you're pussy using an AI as a "test booster" and not just pinning actual androgenic steroids. Probably went this route because your child who cant source or a retard who cant into Crypto currencies.
>>77245475>not just pinning actual androgenic steroids. It's bad for health long-term and shuts down HPTA axis.
>>77245478>Uh but the perma shutdown and long term side effects Pussy, and an ignorant retard.
>>77245485You sound upset and low T.
>>772454942.5g of Gear actually. Right VG a Lil sore
>>77245516Enjoy premature aging.
>>77245519You know Estrogens are neuroprotective and promote HDL increase....Like I said you're a retarded child
start arguing with the retarded teenager.In all fields and move on.
>>77245522>You know Estrogens are neuroprotectiveThey're not, aromatase inhibitors are. >Alzheimer's Biomarkers Tied to Endogenous Estrogen Exposure in Womenhttps://www.medpagetoday.com/neurology/alzheimersdisease/93486>FDA-Approved Drug Combo Rescues Alzheimer’s in Micehttps://lifespan.io/fda-approved-drug-combo-rescues-alzheimers-in-mice/Letrozole was chosen to target neuronal Alzheimer’s signatures, and irinotecan is for glial cell signatures. The EMR analysis revealed that both were associated with a significantly lower risk of Alzheimer’s. Letrozole showed a relative risk of 0.466, while irinotecan had a risk of 0.195, meaning that patients who took irinotecan had an 80.5% lower risk of being diagnosed with Alzheimer’s compared to their matched control group.>Association Between Hormone-Modulating Breast Cancer Therapies and Incidence of Neurodegenerative Outcomes for Women With Breast Cancerhttps://jamanetwork.com/journals/jamanetworkopen/fullarticle/2763234In this cohort study of 57843 perimenopausal- to postmenopausal-aged women with breast cancer, exposure to hormone-modulating therapy (tamoxifen and aromatase inhibitors, especially exemestane) was associated with a significant decrease in the number of women who received a diagnosis of neurodegenerative disease, most specifically Alzheimer disease.For AD, HMTs (such as estrogen therapy) have been shown to be associated with the onset of AD,34 whereas estrogen therapy has been shown to be ineffective as a treatment for those with a diagnosis of AD.35-43 Similarly, the failure of trials evaluating the use of SERMs in the treatment of AD could be due to the fact that the intervention was started past the therapeutic window for HMTs.18,44-46 Here, we show the beneficial effects of exposure to HMT as a prophylactic treatment for the potential prevention of AD.>Like I said you're a retarded childI know more about biochemistry than you will ever will, for i am a great alchemist.
>>77245549>You know Estrogens are neuroprotective>They're not, aromatase inhibitors are. >reduces alzheimers in miceThere's no need to read your AI copy pasted drivel. Aromtase inhibitors are an old drug class. None are used for Alzheimers or the treatment of any mental condition or anything beyond lowering Estrogens for a specific purpose, mostly halting Estrogen sensitive breast cancers.Lmfao Dunning Kruger animal, neck yourself
>>77245557Pathetic mortal, usage of aromatase inhibitors literally decreases risk of alzheimer's disease and related dementias in humans, and treatment with estrogen fails at it. >Association Between Hormone-Modulating Breast Cancer Therapies and Incidence of Neurodegenerative Outcomes for Women With Breast Cancerhttps://jamanetwork.com/journals/jamanetworkopen/fullarticle/2763234In this cohort study of 57843 perimenopausal- to postmenopausal-aged women with breast cancer, exposure to hormone-modulating therapy (tamoxifen and aromatase inhibitors, especially exemestane) was associated with a significant decrease in the number of women who received a diagnosis of neurodegenerative disease, most specifically Alzheimer disease.For AD, HMTs (such as estrogen therapy) have been shown to be associated with the onset of AD,34 whereas estrogen therapy has been shown to be ineffective as a treatment for those with a diagnosis of AD.35-43 Similarly, the failure of trials evaluating the use of SERMs in the treatment of AD could be due to the fact that the intervention was started past the therapeutic window for HMTs.18,44-46 Here, we show the beneficial effects of exposure to HMT as a prophylactic treatment for the potential prevention of AD.
>>77245570Instead of copy pasting the same bullshit you dont understand, ask your Chatbot what do the Estrogen Receptors of the brain do when agonized? You embarass your entire peasant bloodline. At least Your ma and pa know the simple retards that they are.
>>77245578>Instead of copy pasting I will continue copypasting because i'm having a lot of fun harasing you with data you cannot disprove. I take great joy in intellectually humiliating you and every lesser men. >ask your Chatbot what do the Estrogen Receptors of the brain do when agonized?I don't care about mechanistic speculation about beneficial effects of estrogen in alzheimer's disease, because outcome data shows it is wrong, since aromatase inhibitors are beneficial in alzheimer's disease, while estrogen treatment fails. >Potential repositioning of exemestane as a neuroprotective agent for Parkinson's diseasehttps://sci-hub.ru/https://pubmed.ncbi.nlm.nih.gov/28770670/The present study examined for the first time the effect of exemestane on the brain. Exemestane is highly lipophilic, and it distributes extensively into tissues, owing to its lipophilicity [59], suggesting that it can readily enter the brain. Our results demonstrated that exemestane activate the Nrf2 signalling pathway, induce gene expression of Nrf2-depensent enzyme genes, and suppress inflammatory responses. It also prevented microglial activation, dopaminergic neurodegeneration, and motor deficits in MPTP-treated mice. Therefore, exemestane repositioning for disease-modifying therapy for PD might be considered, in addition to its current usage in breast cancer.
Don't fuck up your hormones just because you can. Male bodies need a little bit of estrogen and it's only a problem when it is too high. Unbalancing your hormones has really bad knock on effects and can cause permanent damage. AI's are only used for people who have too high estrogen (usually from steroid injections) not for casual use.
>>77245629>Male bodies need a little bit of estrogenTrue, and exemestane, even at high doses (25-50mg), reduces estrogen only by 30-40% while raising free testosterone by more than 100%. >Pharmacokinetics and Dose Finding of a Potent Aromatase Inhibitor, Aromasin (Exemestane), in Young Maleshttps://www.researchgate.net/publication/8963583_Pharmacokinetics_and_Dose_Finding_of_a_Potent_Aromatase_Inhibitor_Aromasin_Exemestane_in_Young_Males#pf3The 25- and 50-mg dosesof daily exemestane had comparable effects in suppressingcirculating estrogen concentrations, with 38 ⫾ 24% (mean ⫾sd; P ⫽ 0.002 vs. baseline) and 32 ⫾ 29% (P ⫽ 0.008) decreasesin estradiol concentrations, 71 ⫾ 12% (P 0.0001) and 74 ⫾12% (P 0.0001) decreases in estrone concentrations, and45 ⫾ 27% (P ⫽ 0.004) and 51 ⫾ 20% (P ⫽ 0.02) decreases inestrone sulfate concentrations after doses of 25 and 50 mg,respectively. There was an increase in circulating testoster-TABLE 1. Clinical characteristics of the study subjectsStudy I(n ⫽ 12)Study II(n ⫽ 10)Race, n (%)White 8 6Black 1 1Hispanic 3 1Other 2Age (yr)Mean ⫾SD 18.8 ⫾ 3.5 19.4 ⫾ 3.8Range 14.0–25.0 14.0 –26.0BMI (kg/m2)Mean ⫾SD 24.0 ⫾ 2.9 25.4 ⫾ 3.0Range 20.0–29.0 20.9 –29.15952 J Clin Endocrinol Metab, December 2003, 88(12):5951–5956 Mauras et al. • Pharmacokinetics of Exemestane in Malesone concentrations after both 25 mg (60 ⫾ 58%; P ⫽ 0.001) and50 mg (56 ⫾ 48%; P ⫽ 0.003) exemestane. Androstenedione concentrations were increased as well after 25 mg (32 ⫾ 36%;P ⫽ 0.004) and 50 mg (47 ⫾ 59%; P ⫽ 0.052) exemestane,respectively (Fig. 1 and Table 2). SHBG concentrations weredecreased by 21 ⫾ 7% (P ⫽ 0.0003) and 19 ⫾ 39% (P ⫽ 0.18)at 25 and 50 mg exemestane, respectively. Free testosteroneconcentrations were increased by 117 ⫾ 74% (P ⫽ 0.0001) and154 ⫾ 95% (P 0.0001) at both doses, due to the decrease inSHBG and the increase in total testosterone.
>>77245456Aromasin is androgenic like DHT and will speed up balding if you are susceptible. I remember reading a study done on rats many yeas ago where aromasin grew the prostate gland of the rat just as much as DHT.Do a Google search on aromasin and hairloss, lots of results.
>>77245714Important point. I take finasteride with it. Will switch to dutasteride if i notice i'm losing hair.
>>77245456Dubs and OP gives himself priapism
OP listen to everyone here. You are a faggot. Either stay natty or pin test. This is the gayest shit I've ever seen on this board in a while.
>>77246398>>77246381>>77245629>>77245522>>77245469This is OP btwhttps://desuarchive.org/fit/thread/77235005/#77238097https://desuarchive.org/fit/thread/76996387/#76996598
>>77246398>Either stay natty or pin test.No reason for me to do either of these.
>>77245732>finasterideoops I accidentally my 3-alpha-androstanediol
>>77246414>3-alpha-androstanediolDoesn't matter since finasteride increases testosterone that increases taurine that acts as GABAa agonist. Learn alchemy more.
>>77246419You look like this >>77246400
>>77245456You can't deny that if you can get to the same level natural it is entirely better in every way except for how long it takes you to get there. But who here knows for sure even one natty that is legitimately massive?
>>77246420I mog you.
>>77246426Mog off right here right now
>>77246432I mog most of the world's population.
>>77246437I'm basically the same height.
>>77246448You don't even exist.
>>77245456Because I'm happy and I dont need to manipulate my hormones to feel a sense of accomplishment
>>77246437No one takes you seriously so it doesn't matter
>>77246437post body, пидpилa
>>77246672Here >>77246400It's this absolute open BBer smaev tier behemoth
>>77246674peak мaмкин cынoчкa physique in russia desu
>>77246680Oh yeah xer titties are growing nicely from all the bathtub chemicals
>>77246669>it doesn't matterIt matters to me since i enjoy mogging lesser men.
>>77246687You mog no one ivan, you wouldnt even mog yourself if we cloned you
>>77246691I mog most of the world's population. It's statistics.
>>77246697so does this guy but you're both dysgenic uglies. a manlet чypкa gets more pussy than you and will fold you in half in a street fight, so what's all that mogging really for
>>77246701>so does this guy True. >what's all that mogging really forAs i said, i enjoy mogging lesser men.
>>77246697People with AIDS and cancer at the same time are also 0.2% of the population who cares when you look like a ftm dyke
>>77246766>People with AIDS and cancer at the same time are also 0.2% Irrelevant. >who cares when you look like a ftm dykeI look very good with 37cm biceps/34cm forearms at 210cm wingspan. I don't even workout for this results, just doing manual labor and acquiring real-world strength and cardio capabilities.
>>77246776You have tits and teenage boy arms
>>77246776нy жeних!
>>77246778I have high-range-average sized biceps while having abnormally long arms. That's lots of meat that makes me look very large in person.
>much taller with much less muscle than average>long skinny legs, wide hips and breasts>underdeveloped penis and testes>no body or facial hairOP have you gotten yourself checked out for klinefelters? you might be able to get a prescription for test
>>77246400squat nigga, squat
>>77246815I have much more muscle mass than average, weighting 95kg while being around 20% bodyfat. Also my dick is 16cm long and i have a lot of chest hair (you can see it in this photo of me). >>77246816>squatAlready have quite overdeveloped posterior chain.
>>77246828this nigga can't be serious
>>77246878Cope.
>>77246828God damnit I fell for the b8 LMAO
>>77245456just take 100mg of equipose
>>77245732>finasteridelol tranny
>>77245456 i feel much better on arimidex and it gets rid of my acnearimidex for hormonal acnechanging pillowcase daily for bacterial acne
>>77245456My test is at 990 and I just sit and play vidya all day.
