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im thinking about starting pio, but i cant find much about it

im two years hrt, been on and off prog for the past 6 months, 5'10'', 66kg/146lbs.

i know the whole point is to gain weight while on it, so should i lose weight before starting? if so, what weight should i aim to be beforehand, and how much should i gain?

i also remember reading somewhere that there is a less risky alternative with the same effects, is this true? is there anything else i should consider taking alongside it, or just in general?

where can i source it in the uk? anything else i should know?

thanks :3
>>
>>40965905
pio is fucking amazing if you do literally anything other than keep exactly the same weight. if you gain weight on it, you grow fat deposits. if you lose weight on it, you lose fat in places you dont want it and what you dont burn gets redistributed to areas you do want it. ive heard it works particularly well with retatrutide.

>i also remember reading somewhere that there is a less risky alternative with the same effects, is this true?
not really. there are similar drugs but none are as potent as pioglitazone. its the reference drug in all studies on fat cell growth and almost nothing else comes close. however...

good things that have helpful effects that go even harder when combined with it include fish oil (adipogenic effects), arginine (mobilises fat deposits through GH related effects), retatrutide (dont combine with arginine), prog (boosts feminine fat deposit lipid uptake) (topical or injection preferred).

do not eat a high sugar diet with this, stomach fat is more sensitive to insulin than other fat sites and youll ruin your results from it. go for high meat and fat content, thats your best bet to maximising results.
>>
>>40966434
I've been on pio for a month and didnt know about the high sugar diet thing, thanks for this
Overall seeing pretty good results so far
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>>40966757
yw fren. abdominal fat responds in an exaggerated manner to high sugar, esp high sugar and fat, so ye.
>>
>>40966434
this is rly helpful ty!!!



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