Hello, /tttt/. I saw a link with a blurb on Google, stating that drinking grapefruit juice can significantly increase estradiol levels in the blood. I also saw an article saying not to drink grapefruit juice while on estradiol because it will increase the amount of estradiol in the bloodstream, causing side effects like breast tenderness, headaches, and nausea.source:https://www.singlecare.com/blog/foods-to-avoid-while-taking-estradiol/It also increases the blood level of progesterone.source:https://www.drugs.com/drug-interactions/estradiol-patch-with-progesterone-1019-3912-2414-0.htmlFor those of you who drank grapefruit juice while taking estradiol or progesterone and spironolactone, what did you experience? Would you recommend doing it? Why or why not?
>>41245810Hey, everyone! OP here. I am on one 0.1 mg estradiol patch every four days and one 50 mg spironolactone tablet every day. I am drinking 1/3 Lunazul tequila and 2/3 cocktail mixer containing grapefruit juice.
>>41245810I thought grapefruit juice interfered with the absorption of pretty much every drug? Or is that only relevant for things taken orally
>>41245810whenever i do this it makes my boobs bigger and more developed. would recommend. idk if honscience tho and diff ppl might respond diff drink grapefruit juice or eat either a half or whole grapefruit (however much u can tolerate) 2-3 times a week at night when u take prog (half life of whatever suppresses the liver enzyme is 72 hrs or so u dont need to eat it every day) >>41246032yeah if u do that on certian other medications it can kill u i think so ppl need to check interactions
