What is PIO and how does it work?Google gives me nothing
>>42099463pioglitazone. it is traditionally a diabetes medication, but one of it's prominent side effects is redistributing fat, primarily to the trunk region. this only really works for ppl w/ lots of estrogen, so dont start it until you've been on hrt for a few years and have already noticed some fat redistribution. start w/ 15mg/day for 3-6 months at a time, with long breaks in between. i can personally vouch for it's effectiveness, my ass and hips ballooned after gaining 30lbs while taking it
>>42099463Start at year 3 of HRT the earliest, you might want to wait untill year 4 just to be safe.
>>42099463Pioglitazone.It is a PPARg agonist. The mechanics of how it works are quite complex; honscientists on this board will not give you a proper explanation. Trannies use it as a fat redistribution enhancement drug, since it encourages distribution of fat towards the lower half of the body (thighs, ass, and so on).If HRT is like a 1/10 in terms of danger pioglitazone would be like a 5/10. The main thing you have to look out for is bone density loss, but there are a lot of other nasty risks you can look into (read the monograph).Most folks will be able to get equivalent fat redistribution effects on just HRT, albeit over a longer period of time. Most of the conditions that would necessitate pioglitazone are things you can go to the doctor and get a legitimate prescription for.
>>42099463also add it builds subcutaneous fat. the soft knd that sits below the skin
>>42099543So its not that useful to get a big assUnless you're an asian girl
>>42099463how the fuck do I gain weight and not get stretch marks? I feel like the moment I start gaining the slightest amount of weight I get fucking stretch marks it sucks :(
>>42099463lol at the amount of eyeliner to make the eyes look bigger
>>42099463>What is PIOa meme>and how does it work?it doesn't
>>42101944>Retarded white suburban manmoder discovers japanese fashion from 2019
>>42101702It gave my friend and I nice butts after gaining using it, I am White and they are Mexican>>42101946onions cope
>>42099463is the girl in the pic trans?
>>42099491iirc doeses below 30mg were not found to be viable for this use. does someone have the study on hand
>>42099491Where can US anons get it from?
>>42107430Study on use of thiazolindinediones in transsexuals> She was commenced on rosiglitazone 2 mg/day and after 14 months of therapy her waist size dropped to 82.5 cms and hip measurement to 94.5 cms and at this point, her right and left thigh measurements were 45×44 cms respectively. Another 6 months of treatment on Rosiglitazone lead to drop in waist & hip measurement to 82×93 cms respectively and an increase in right and left thigh measurements to 49×47 cms respectively, which gave her a more desirable body image.Rosiglitazone is in the same class of pio
>>42107510>waist size dropped to 82.5 cmsWhat the fuckMy waist size is 68cm and I've never used pio or any similar meds
