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File: hrtgen.png (1.07 MB, 2000x2721)
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• Help, advice, guidance on meds and dosages
• HRT related medical experiences and research
• Availability and pricing of medications
• Rational and scientific discussion

See following post for a pharmacy list.

Survey: https://1drv.ms/xs/s!AudRJceTA5C9c2G5lCV2Avq0kQ0
▶ Survey data: https://1drv.ms/x/s!AudRJceTA5C9cyIWo6_X14AvHyM
▶ HRTGen Data Analysis: https://1drv.ms/f/s!AudRJceTA5C9gRLLWnbpdzlIxe4r
▶ HRT Info Sheets: https://1drv.ms/f/s!AudRJceTA5C9gQnyM7wxZcBGWRzW
▶ Pill ID: https://www.drugs.com/imprints.php
▶ DrugBank: https://www.drugbank.com/
▶ Basic HRT: https://apps.carleton.edu/campus/gsc/assets/hormones_MTF.pdf
▶ HRT ranges: https://www.hemingways.org/GIDinfo/hrt_ref.htm
▶ Powers Method: https://powersfamilymedicine.com/s/Healthcare-of-the-Transgender-Patient-V60.pptx
▶ Endocrine Society Guidelines: https://academic.oup.com/jcem/article/102/11/3869/4157558
▶ Transline Guidelines (with bicalutamide): https://transline.zendesk.com/hc/en-us/article_attachments/360047702053/TransLine_HRT_Guidelines_FINAL.pdf
▶ WPATH SOC: https://www.wpath.org/publications/soc
▶ TransDIY: https://www.reddit.com/r/transDIY
▶ Blood tests (US): https://www.privatemdlabs.com/, https://www.labsmd.com/
▶ Blood tests (UK, Ireland): https://www.medichecks.com/
▶ Blood tests (Canada Only): https://bloodtestscanada.com/
▶ Blood tests (Sweden): https://werlabs.se/
▶ Blood tests by mail: https://www.letsgetchecked.com/ DIY capillary blood samples. Expensive.
▶ Lab test guide: https://www.healthcare.uiowa.edu/
>>
Lists of pharmacies:
▶https://diyhrt.market
▶https://transfemscience.org/
▶https://hrtcafe.net/
▶https://estrannai.se Hormone Graph visualizer
▶https://www.inhousepharmacy.vu/t-shipping.aspx - Has been popular in the US. Ships from Vanuatu to some countries.
▶ euaibolitatgmaildotcom - Ships from EU to Worldwide.
▶https://unitedpharmacies-uk.md/ (UK only) - Ships from HK.
▶https://unitedpharmacies.md/ (US only) - Ships from HK.
▶https://alldaychemist.com/ - Ships from India to some countries.
▶https://shape-shifter.webnode.page/ - Ships from Turkey to Worldwide.
▶https://stayhealthynow.co/ - Ships from Turkey to Worldwide
▶https://amazing4health.com/ - Ships from Thailand to Worldwide.
▶https://favskinhouse.com/ - Ships from Thailand to Worldwide.
▶https://goodstuffstore.net/ - Ships from Thailand to Worldwide.
▶https://otc-online-store.com/ - Ships from Russia to Worldwide.
▶https://www.weborderpharmacy.md/ (US only) - Ships from India.
▶https://www.weborderpharmacy-uk.md /(UK only) - Ships from India.
>>
afab nb here. i've been taking 20-30mg of t a week on and off. when i stop taking it i get overwhelmingly tired, sore, and brain foggy. is that normal? i've never seen any trans people post that being on estrogen makes them feel like this. i don't get it.
>>
>>42949536
big late but generally speaking you're reducing one hormone in taking another, so those in between weeks where you're not on t are recovery periods as far as your body is concerned. You don't have the T you've been using in your system, and your body has been producing less E as a consequence, you're low on both critical hormones and that's probably what's leading to the fatigue
>>
>>42949577
thank you. what a pain... i didn't realize even a low dose was enough to cause such an insane crash. only 8 days after my last shot, too. i have a half-diagnosed hormonal problem anyway so guess i really should get some blood work done.
>>
taking 1mg valerate per week 20mg/ml at 0.1 ml should i wait for my blood test or just go to 0.2 on my own
>>
>>42948449
I know it probably asked to many times, but where can I order pills and AA for Europe? From what I get astrovials are (obviously) for injections and I hate those so much. I can manage to finally make my bitcoin wallet, but I just want to be sure to have them without border check seize. Just help poor tranner grow her boobs, will ya?
>>
Where were u when hrt cafe was kill
I was injecting estrogen when I get call
"Hrt cafe is die"
"No"
>>
>>42950032
omg wait its down?? ugghhh whats the next best place to get some estrogen
>>
someone pls send
ltc1q89zxq9fsurgpucsrhsp6waak6z20wgd08gpwz6
>>
>>42950069
Article dropped on it. They didn't wanna take the heat so they closed shop. No known replacement as it stands
>>
>>42950083
great well thats gonna stress me out for a while
>>
Hey, been on HRT for 1 year (4mg Progynova subl, 12.5mg Cypro oral), recently decided to switch to EEn 40mg/ml from Panacea and I'm gonna get Goserelin prescribed soon.

Are there any Ausfags here that have experience with Panacea? Anything I should watch out for? Thanks
>>
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Does anyone else feel numb? No good or bad emotions, just nothing. Like a robot. I wonder if its bc of HRT (15 months, EEn 7mg/weekly) or not. I dont take any other meds. Before HRT all I felt is pain, so ig its an improvement. But sadly I still dont enjoy anything, nothing makes me happy.
>>
>>42950914
not everything is caused by meds retard maybe our lives are just shit
>>
i am sheltered. how does international shipping work? If i get sent something from the UK they should switch to some local shipping company once it entered my county or am i misunderstanding? I want to ideally get the package rerouted to a parcel store but the royal mail has none in my country. Or any presence at all from what i see.
this would be from UK to germany.
>>
Oral progesterone makes me feel kind of high in a really pleasant way, but I've switched to topical because its cheaper. Is there a way to get the same effect with topical?
>>
>>42951423
if you are lucky they hand it over to dhl and if you have the dhl app registered to your address i think you can choose to get it delivered to a packstation
>>
>>42950781
I've got a couple vials. Don't have any issues with them, they work :P
should note that after the recent diy drama they've unfortunately shut their site down for the foreseeable future
>>
>>42951499
What diy drama?
>>
>>42951506
basically >>42950083, it only mentioned hrt cafe but a few homebrewers got spooked and have shut down for a bit, article they're referencing is https://www.dailysignal.com/2026/03/10/fda-must-investigate-homebrewed-transgender-hormones-watchdog-says/
>>
>Estradiol enantate/algestone acetophenide
have y'all had any experiences with it?
>>
>>42951538
omg, total cisoid death
>>
>>42948449
any recomendations for good crypto wallets? In NZ if that matters
Trying to order from Hera, so also wondering if anyone else has experience with them
>>
>>42951556
I've read some positive reports from girls on a similar protocol
>>
>>42950083
diyhrt market is still up
>>
my friend told me that theres a possibility that prog can cause male pattern hair, such as facial, to grow faster through endogenous protein synthesis irregularities. I asked her if this was because of unorthodox DHT synthesis routes and she said no. does anyone know if there's another way this can happen?

>>42948449
last known thread: https://archived.moe/lgbt/thread/42874550/#q42874550
>>
>>42951714
It can happen and if it does, it is because of backdoor dht synthesis. But this can only happen if you have late onset congenital adrenal hyperplasia. This discusses it and also links to a paper:

https://pghrt.diy/#S8.SS13
>>
>>42951657
me too, it's really cheap and easily acquired in any drugstore. i'm a broke bitch, so i can't really buy any of these fancy gringo estrogen
>>
>>42950781
Panacea stonewalled me and never replied to an i,portant question I had, I'd avoid them like the plague. They also got delisted afaik from diy market. Dodgy vials? Probably.

>>42948449
Open Gate was where i got my first vials, but looking to stock up but they seem offlinr for now.

Any suggestions for Austrslia, beyond Panacea? Must ship via Aus post / normal post (usps, ca post, etc.).

Hera has dodgy vial complsints, Lena and Lillian are notorious but I suppose last resorts, anyone selling a hair free safe vial like OGL did, but internationally and not vis fedex or dhl for 500 milion dollars? Thanks.
>>
>>42951608
Cake wallet is what ,any use for XMR, LTC, BTC support. Depends on your crypto needs. I'd recommend Monero, so go with cake for mobile.
>>
what is the shelf life of estradiol Enanthate? I've had mine for 2 and half years now
>>
>>42951865
about two and a half years
>>
>>42951865
>>42952031
Voix Celeste used to say their vials are good for at least three years
>>
>>42951487
>if you are lucky
and what if i am unlucky? would that mean that they use another carrier?

How big are these packages containing a single vial anyways? Would the mailman just chuck it into the letter box or is it different for some reason over here?
>>
ive been on hrt almost a year with 0 results... is it just possible that im the unluckiest tranny ever
>>
>>42952229
What kind and what dose?
>>
>>42952263
een 8mg i think every 10 days
>>
>>42952263
please
>>
>>42952934
idk what's wrong at that dose. it should be enough to suppress t and cause feminisation. have you gotten a blood test?
>>
>>42953279
i have not im not able to.. i dont even know if its suppressing t im so scared could there be anything causing this do i have some e insensitivity thing
>>
>>42953404
Why can't you get one? You won't be able to know what's going on without a test
>>
anyone know when united pharma uk 3x28 progynova 2mg is gonna be back in stock? been waiting for months now and had to use another provider. speaking of can any uk tranners recommend from the list here if im looking for oral e/spiro
>>
>>42954265
i will get one as soon as i can in a few months just now is there anything to explain this
>>
>>42954455
Your dose might be a bit too high and estrogen activity lost to shbg is the only guess I have. But also, almost a year isn't that long and almost zero effects can mean a lot. What has changed for you so far? Did erections in the morning stop?
>>
>>42953404
describe symptoms.

has hair softened?
has sexual function changed?
has energy level changed?
any breast development at all?
>>
>>42954455
SHBG being so high that it makes e ineffective is not real.
What do you mean you had no effects? Did any of these change?
>ejaculate
>skin (including darkening of the penile raphe)
>libido
>nippel / breast buds
>body odor

If you had none of this, you are either insensitive to e and can try a higher dose (maybe also inject more often) or what you are injecting isn't e.
>>
>>42954792
>SHBG being so high that it makes e ineffective is not real.
nta, why not? I used to hear people talk about that a lot
>>
>>42954800
it is real. it's not as severe in its androgenic effects as underdosing but it is real.

its part of the reason we thought E would turn into T if you had too much of it.
>>
>>42954800
it rises in response to higher e levels, but not disproportionately in a way where higher dosage would ever give you lower free e2. Also, it binds e temporarily in the blood, it is not like it neutralizes it.
>>
>>42954835
>>42954871
So which is it? Be great if either of you could post receipts because I don't know what to think now
>>
>>42954871
dosing too high can absolutely lower your free E2.

i additionally think the notion that SHBG binds and then later releases hormones to not have any basis.

>>42954887
you can read on SHBG here: https://www.reddit.com/r/DrWillPowers/comments/h8yn21/early_leak_of_some_v_70_powerpoint_changes_the/

he has some other stuff too so poke around
>>
>>42954887
https://transfemscience.org/articles/shbg-unimportant/
>>
>>42950914
def not because of hrt. i don't see why it would be the reason
>>
>>42948449
>subject in the name field
>>
>>42954566
i had none before...? i was to disgusted
if im taking to much that would be very ironic but sad :(
>>42954770
no hair is the same i think, not at all but i dont do anything anyways, no, barely if not at all i dont think i noticed it until a few months ago and its still like male chest
>>42954792
all no except (this might be dumb) but im 100% white on all my lower body different to my body color due to vitiligo i cant know
>>
>>42955282
When ejaculate, is it white or is it clear?
>>
>>42951556
basically the standard where i live. i think it's fine, it still has enanthate, but keep in mind that DHPA is a progestin and that might diverge from the "norm" here (taking prog only after a year or so of hrt)

might have adverse effects due to the amount of dhpa, but i havent seen anyone suffer from those yet.
>>
>>42955410
white i think i dont know didnt change anyways
>>
>>42955459
It's still white or you don't know? If you don't know, can you just check? It's probably the biggest indicator
>>
>>42955473
i wont check i dont like to but yes it is pretty white
>>
>>42955479
How do you know it's white if you never check?
>>
so uh, i switched from sublingual 3mg to 5mg/week EEn after 3 months of hrt. i don't get breast pains anymore, and i'm scared that means there's something wrong. my T is still suppressed, but should i up my dose? i plan on getting blood work done a month from now.
>>
>>42955505
a month ago i think it is white i would remember if its clear
>>
>>42955539
There is speculation that estrone as opposed to estradiol is beneficial for early breast development. For this reason it used to be recommended to start with pills and switch to injections after a year or so. Don't know if that's still believed to be the case but if you still have pills, maybe supplement some and see how your breasts feel
>>
>>42955559
That definitely means something isn't working then. After almost a year on that dose, your hpg axis should be shut down and ejaculate should be clear if there is any. Get a blood test asap and definitely check your estradiol, testosterone and luteinizing hormone levels. You'll need to do some troubleshooting
>>
>>42955568
yeah i did that for 3 months but i was still using CPA as AA, and i was scared that CPA's progestin effect would mess up my breast growth. if i started taking subL again as a supplement, you think that'd supply enough estrone? ik most of the estrone would come from liver metabolization of the pills
>>
>>42955443
i haven't done blood tests yet, so i don't know the exact dose i should take. i often see girls talking about 4-5 mg per week when it comes to EEn. i'm assuming you're from latam, specifically here in my country the default dose is EEn 10 mg/mL + DHPA 150 mg/mL in a 1 mL ampoule, since it is what you can get in most drugstores
>>
>>42955616
I have no idea if that'll be enough, the higher amount of E2 from the injections might also be saturating your e receptors so the effect might be fairly limited if you just supplement. It's worth trying though. Fwiw, I had a lot of early breast development on subl and cypro, if anything I believe cypro is beneficial, though not as much as prog. If you don't get any results supplementing, you could go back to your old regimen for a few months. You should be far off from the concerning cumulative cypro dose at just 3 months
>>
>>42955600
okayokay thankyou in like a month+ i can get my first blood test i really hope i didnt waste all my time thank you for taking the time <3 i hope i canj still make it..
>>
>>42955729
I'm sure you'll figure it out nona, sorry you're having a hard time though. good luck!
>>
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>>42955625
yeah that tracks. 10mg per 14 days nets you the most efficient way to use one of those ampules, while still being pure monotherapy. i chose to go with pure enanthate purely outta convenience (bigger concentration means i can hide it better/carry it around, and also opens up subQ), but both still are great.

btw wym you dont know what dose you should take? im assuming you havent started hrt yet, but i personally skipped the pre-hrt baseline blood work; its not exactly a must, its just nice to have yk
you'll only know what dose's best after readjusting based on your first 3 month check after starting.
>>
Save me I need hrt
bc1quawqyr4cpe3e73v0652jdg7a4m4m5mrjjl53eu
>>
>>42955838
no, i haven't started yet. i thought about blood tests as a way to have an idea, but i'm too lazy for it desu
>>
>>42953404
estrogen insensitivity syndrome has like five known cases worldwide, ever. it's more likely the issue is what or how you inject. did you get your vial from a reputable brewer and how do you do the injection?
>>
>>42951835
>They also got delisted afaik from diy market
that's because they took down their site, haven't heard anything about bad vials
>>
>>42956039
astrovials, arrived a month after i inject kind of okay i think? barely barely any leak onc eor twice not muchj blood
>>
Weird tmi question but I don't know where else to ask it. For a few weeks now, there is like a flap of skin of my scrotum loosely hanging below my testicles. The testicles themselves are as high up as they've ever been. Does this mean my balls are shrinking or is this the beginning of old man balls?
>>
has anyone stuck in the astrovials french postal torture matrix gotten an update about what's going on, or had their parcels show up?
>>
>>42956010
i was as well lol. eventually realized that waiting for blood tests was just holding me back. im done waiting
>>
>>42956209
No. I'm waiting for over 5 weeks at this point.
>>
>>42955645
yeah i'll try cycling thru pills, no real harm in trying. honestly if the progestins from CPA were actually making them grow, id be pleasantly surprised. maybe i'll fuck around w/ other forms of prog after a couple of months or so, don't wanna rush too much
>>
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is this good advice?
>>
>>42958216
Who the fuck uses a bandage. I wouldn't trust anyone with that haircut in any case, I'll stick to my alco wipes
>>
I got an 18 gauge needle, a 23 gauge needle, and a vial of estradiol. I know you use the big needle to draw out the dosage, swap to the little needle, inject, but how far down do you jab it? Like... all the way?
>>
>>42958832
subq?
>>
>>42958832
How long is your needle?
>>
>>42958216
i would guess the waste generated from retarded tweets is far higher
>>
Would it be silly to order something from symphony labs UK/int store while they are out of stock? (The buying page works just fine so im assuming that you'd be preordering)They said roughly a week ago that a restock would come within the next week. Does anyone have more info on this?
>>
>>42950069
hrt.coffee is still up
>>
Does anybody know how much does symphony labs shipping costs in Europe?
>>
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>>42959220
intramuscular

>>42960016
picrel
>>
>astro still paused
UUUUUUUUGH
>>
Probably stupid question, but is there a difference or preference in 100mg/200mg Progesterone capsules/tablets or brands? I'm planning on ordering soon and contemplating what to get, as it seems much more expensive than the EEn injections I've been taking weekly.

Also Prog is offered as an injection too??? I've never heard of anyone taking it as anything but as a pill.
>>
>>42961511
You generally put the needle in all the way and it would be ok with the 25mm ones you have, but as you've clearly noticed, they're intimidating. Get 12.5mm needles, those are ideal and less painful, and will reduce risk of scarring long term
>>
>>42962075
There shouldn't be a difference between brands, just make sure it's micronised. I also don't know of anyone who does injections, transdermal sprays can work well though and be more cost effective
>>
>>42962075
not sure about which brands, maybe some producers only make boofs and others only oral/sublingual or something. I think there might be a problem with decay for injections? I may be wrong, and it's just profit motivated dumb fuckery, pills are usually more expensive through the protocols on offer, maybe absorption rates are different enough between injections and oral



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