the lying new york crimes is going to do a story on diy
>>43108936nigger nigger nigger
>>43108936Journalists are all fucking snakes and liars.
>>43108936The online trans community is very similar to the online incel community. Basically a bunch of autistic basement dwellers finding solace with other creeps like themselves. They stay in these fucked up echo chambers and that’s why they’re more likely to kill themselves instead of just going out and living life. You can tell who these people are by the lingo they use. Passoid, cishet, pooner hon etc. It’s about time the mainstream media blows the story out of the water.
>>43108936the establishment dem media is hitler lite
>>43108936>emphasis on trans teensoh im sure
>>43108936Powers should know better than this with his autism. I guess this is the class element showing through.
>>43108936lmao my gut instinct was, "this reporter is a cishon, guaranteed" and i looked her, BINGO!based on her wiki, she writes pro black, pro neurodivergence, antiwhite, and focuses on tech and science (unclear if in favor or against). she is going to spin this article as DIY being irresponsible and that they need to crack down on it for everyone to prevent underage people from accessing it. people on the reddit thread already found transphobic links and NYT is transphobic too.
>>43108936>drwillpowerslulz
>>43108936You don't hate journalists enough.
>>43108992Yep.
>>43110650We should spam the number telling her that diy is safe and its only because of republicans that we’re thinking about using it.
>>43108936jfc might as well be talking to fox newsnyt has been taken over by nazi-lite leadership
>>43109152as usual his ego is more interested in getting his name in the paper than anything else
>>43108936oh my fucking god
>>43111150true
UK bans DIY, now suddenly anti DIY articles going to pop up in US media.These cunts are so blatant
>>43108936how is this guy so naive, how does he not know?
>>43108936it is every trannies sacred duty to remain silent when journalists talk
>>43115164Powers is an idiot. He just happens to have a medical degree and is willing to try weird shit, but he's an example of the Dunning-Kreuger effect.
>>43115179well maybe he's provided some good insights but this is just sad
>>43115191He needs to stay in his lane tbhon, which is basically testing out and documenting honscience theories so that there's official documentation for them.
>>43108936
>>43108936>autistic retard with an MD falls for the "both sides" griftLol. I'm sure this will go just as planned.>>43110650Literally anyone who has ever taken a monday off for Martin Luther King day is "anti white" to you spergs
>>43108936Finally someone is helping us
>>43109152his arrogance is insane and would be funny if he was just some random pseud and didn't have thousands of vulnerable people, whom he has openly expressed disdain for, depending on him
>>43115288>whom he has openly expressed disdain forWhen did Powers do that?
>>43115269>helping usHelping us into the next life
>>43115669buh i aint got the api limits nor time to search all his comments for proof/produce a dossiergo read his comment n post history, his savior god complex is crazy and there's tons of examples where his hubris pokes through, there's a reason most itt aren't a fan
>>43115928Powers is based. Is he a non-neurotypical weirdo who makes a fool of himself on reddit? Yes. Has he said transphobic things on reddit? Yes. At the end of the day he is a very good doctor who has done a lot to educate people on HRT. Also he has giant cats.
>>43116002Will Powers is that you???
>>43116002>who has done a lot to educate people on HRTdebatable
>>43116002>who has done a lot to educate people on HRTwhat education beyond woowoo hypotheticalsthe most he's done is 'educate' (see: take legal liability) endos on adopting rectal progesterone
>>43116083https://youtu.be/qGuvDlYDNzU?si=f6YAEbzYFMptYs-NHe literally does HRT education to endos you retard.
>>43116083>gives education on HRT>how does he educate on HRT?????jesus christ
>>43116130nta but 50% of this is honscience
>>43116130>>43116006probablythat or his mthfr gremlin>>43116139do you know how to read or do you take everything at face value
>>43108936I hope we see the end of "transgender medicine" soon, I'm so tired of this insanity.
>>43116161>honscienceTbf honscience is real.Dairy causes man faceMeat causes man faceProgesterone without high levels of estrogen causes man faceVitamin a supps cause man face
>>43116195ok lol
>>43116161found the anti DIY reddit hon with hair legs she's too autistic to shave
>>43116221hi babytroon
>>43116235it's not denying it
>ITT trannies spend their energy shitting on an autistic doctor who gave HRT to thousands of trannies, has helped many access transition related care and even offered it for free in many cases, purity testing him and smugly gloating they know more about HRT while not passing and with spirohon tube boobs.
>>43116359>purity testing him and smugly gloating they know more about HRTnigga he directly threatened to sue aly from transfemscience for fact checking him get real
>>43116130>YOU SHOULD HECKIN APPLY ANDROGEL TO YOUR BREASTS>LIKE TRANSCRIPTION FACTORS OR SOMETHING, WAOWO>YOU'LL BE TANNER 9 IN NO TIME HON!!!
>>43116359I have respect for him when it comes to providing healthcare but he needs someone to slap him half of the time because he's equal parts helpful and overconfident.
>>43116359
>>43115263take your meds. she won a pulitzer for her antiwhiteism
>>43110739looks like she could benefit from diy
>>43116743expanded facial planes, it's over for her
>>4311674334 years old
>>43116207Sorry facts upset you
>>43116743cishon gatekeeping transwomen out of insecurity, a tale as old as time. She probably got asked if she was trans at some point and this lead her down the rabbit hole.
>>43116440testosterone causes an intake in growth hormones, which, surprise, grows shit. Congratulations
>>43117171Isn't the theory about aromatizing T into other estrogens? Seems like you should just have high AA dose + low/moderate E dose to have tons of free T (and also get the high LH/FSH benefits) instead.
>>43117184>tons of free TI hope you like going bald
>>43117184>Isn't the theory about aromatizing T into other estrogens?Sounds insane
>>43117315nta but that's actually how hormones work...test and estrogen and all their derivatives exist in a feedback loop and get constantly cycled between each other. women have test and men have estrogen and both are necessary for health function.
>>43117264>>43117315The idea is you block your T receptors with Bica while keeping a low dose of E2. This boosts your LH/FSH which drives some important development, notably tertiary breast branching. Then, the elevated, but blocked T aromatizes into different estrogens locally in fatty tissue, with the different estrogens contributing to feminization in different ways. I think Powers is trying to just use exogenous T to produce that aromatization effect, but it's still missing the benefits of elevated LH/FSH.
>>43117378>>43117360Yeah nah, fuck that. How are you both this dense? Do you think anyone else here is as gullible?Take testosterone = masculine Take estrogen = feminine Anything else is lies, im sorry you've been lied to
>>43117387lol. this has about as much value as a statement as "trannies are men because its simple biology"
>>43117419Ok you rub testosterone on your tits, you dumb fuck
>>43117171his theory is that you get more free E by using T, which doesnt make any sense because you can just take more E. but of course, when asked about it, he just says he has patients with super rare mutations in which higher total E leads to lower free E and when he tried this on them their boobs grew a lot with stretch marks and all that>>43117184>>43117378this theory is not from powers. Im highly skeptical about the high gonadotropins (LH, FSH) theory because it is entirely based on one single study>>43117264>>43117315AAs can completely block androgen receptors (not a fan of bica), high circulating T undergoes peripheral aromatization and converts to E
>>43117456I think for the aromatization stuff you could just do some compounded estrogen cream that contains E1-E4 but the LH/FSH stuff is important as well. Can't boost those without boosting T though unless you don't have testes, so you need something to block androgen receptors as well.
>>43108936Talking to reporters is like talking to the cops. Ugh. Stupid Redditors don’t know that the reporter is always going to be friendly and sympathetic when talking to you, then turn around and write a hit piece.Idiots.
>>43117472>Free testosterone is the unbound form that enters cells and is converted into dihydrotestosterone (DHT) by the 5-alpha reductase enzymeDont want to be bald
>>43117472Overall I think it's gonna be highly individualized. Like I have T production that's really easily suppressed (80pg/mL E2 on patches was enough to suppress T from ~600ng/dL to 30 ng/dL) and a genetic predisposition to aromatizing free T into E. Do you have the LH/FSH study? I am curious if I can maybe find more.
>>43117529ok
>>43115288I really wish powers would fucking die.He tries to gaslight ftms into repression and gives them estrogen too.He should go away.
>>43117489>LH/FSH stuff is important as wellWhy would a mtf want to increase sperm count?
>>43117529Bicalutamide blocks the androgen receptor, so free DHT also doesn't bind to anything. But you can also take Dutasteride if you want to.
>>43116002He actively commits malpractice, stfu
>>43117565>free DHT also doesn't bind to anything.Unbound (free) DHT is biologically active and directly influences tissues by easily entering cells to interact with androgen receptors, making it more potent than bound DHT. Once free, it binds to these receptors to exert effects on hair follicles (potentially causing miniaturization and hair loss), skin (increasing sebum production and acne), the prostate (contributing to growth), and secondary sexual characteristics. Because it is not attached to carrier proteins like sex hormone-binding globulin (SHBG) or albumin, free DHT circulates in the bloodstream and is the primary form measured to assess immediate hormonal activity in the body.
>>43108992Even the ones that are honestly thinking they're one of "good ones" are more interested in telling a story than setting the facts straight.
>>43116712DNA testing for cancer risk markers is white genocide, got it
>>43117562For breast growth. Also wouldn't be surprised if it does something for girlies who develop adrenal issues on HRT.
>>43117589When androgen receptors (AR) are blocked, Dihydrotestosterone (DHT) cannot bind to the receptor, preventing the hormone from triggering its transcriptional program or cellular effects. Consequently, DHT levels themselves remain unchanged because the blockade affects the receptor's ability to receive signals, not the hormone's production or circulation
>>43117589Did you read the fact that your androgen receptors are blocked? Again, it cannot bind to blocked receptors, rendering it inert. Stop using ChatGPT and start using your eyes.
>>43117539theres a doc from one person explaining everything I will try to find itstudy:https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1365-2265.1982.tb00728.x
>>43117559lol what
>>43117646I think I have the doc you're talking about.
>>43117670post it please
>>43117621I know, i posted this >>43117603However, i wont ever take testosterone gel, sorry. I'll let other anons enjoy that pleasure
Estrogen is the primary hormone responsible for promoting breast growth, while testosterone (and other androgens) generally inhibits or counteracts this development. Estrogen's Role: Estrogen triggers breast development by stimulating the proliferation of mammary glands and ductal tissue, mimicking the process of female puberty. Higher doses of estrogen do not necessarily result in greater breast growth; instead, genetics determine the ultimate size and shape, with the hormone acting as the "trigger" for the genetically predetermined potential. Testosterone's Role: Testosterone normally keeps male breast tissue small by opposing estrogen's effects. In the context of breast growth, elevated testosterone levels can inhibit breast development, whereas suppressing testosterone (often via anti-androgens or orchiectomy) is a critical step to allow estrogen to induce growth effectively.
>>43117680https://drive.google.com/file/d/1D3YcOXDplwlbLLIcZTw21gQW018IthWM/view?usp=drivesdkThink this is the one.
>>43117703yes its this oneonly the part about gonadotropins is relevant tho, the rest is kind of dumb. I would just do this post orchi/srs or with second gen NSAAs (enzalutamide, apalutamide, darolutamide)
>>43117756I know someone who is trying clomid for increased gonadotropins post orchi. I was just already considering Bica since I seem to get above average androgenization from prog and having too high E2 gives me headaches.
>>43117565>BicalutamideYou mean the drug that makes you piss yourself?
>>43117900That's Spiro
>>43117793you dont need to do anything post orchi. although your testicles wont produce activin anymore, lower E levels (100-200pg/ml) or cycling E will still give you enough gonadotropin levelspersonally, I wouldnt take bica, mostly because of this:https://en.wikipedia.org/wiki/Pharmacology_of_bicalutamide#Selective_androgen_receptor_modulator-like_activityand because bica isnt THAT good at blocking high androgen levels>I seem to get above average androgenization from progyou can test for NCCAH>>43117900unreal
>>43117900bica is the drug that blows up your liver RETARD
>>43117926Unfortunately I'm stuck with mostly useless doctors rn who won't test me for NCCAH. It's something I've considered since I fit some of the symptom profile and also adrenal issues run in my family.
>>43118051cant you just pay for it? I suppose its cheap to test just for that where you live
>>43118110Unfortunately no. Needs a doctor's order and some of the tests are an all day thing.
>>43118204grim
>>43118015no thats flutamide
>>43117793>considering Bica since I seem to get above average androgenization from progI have the same issue and had the best feminization/results on it, esp. wrt. breasts, though I think it was moreso due to the T blocking than gonadotrophins (i have really bad adrenal production)having no T sucks though, I can feel the effect it has on my circulation, so trialing duta in the meantime>>43117926>https://en.wikipedia.org/wiki/Pharmacology_of_bicalutamide#Selective_androgen_receptor_modulator-like_activityhonestly i think it's overblown and moreso relevant to T-dominant endocrine systems>and because bica isnt THAT good at blocking high androgen levelson mono it's quite good, tho I've not tested it without an adjunct DHT blocker (was also on Fin)i tried mono + fin for 2 years and noticed differences (mainly bodyhair/skin tone/hair oiliness) within weeks of hitting Bica steady state (frontloaded it lol, picrel)
>>43110650>You should only use LEGAL routes but i would never ever ever stand up for your right to use them.
>>43118633>honestly i think it's overblown and moreso relevant to T-dominant endocrine systemsnot overblown. bica counteracts demasculinization even after castration>on mono it's quite goodits not>I've not tested it without an adjunct DHT blockerwasnt mono thenT fully converts to DHT on tissues with high expression of 5ard like prostate, scalp, skin, etc. if there is too much T converting, bica is simply unable to out compete DHT, even with 300mg/day
>>43118757do u have proof for your (rather strong) assertions beyond extrapolations/theoreticals/assumptions drawn from rat/mouse models, vitro studies and mens cancer trials, because there's many people on bica adjunct to mono without 5ar inhibitors doing finelike i understand the point, but it's whether it actually matters in practice, because i've been caught in these loops before when it turned out it was a waste of time mulling such>t. works fine on my machine
>>43118943youre kidding right? I posted proof>rat/mouse models, vitro studieslow quality>mens cancer trialshigh qualitywhy are you ignoring prostate cancer studies? have you read the full wiki page?>there's many people on bica adjunct to mono without 5ar inhibitors doing fineIm not saying bica doesnt work. Im saying its not ideal, especially if youre really young because of bone masculinization. definitely not worth using to test if the lh/fsh theory works, I wouldnt do it. I recommend bica often to people that ask me. I used bica and duta for years. I wouldnt use bica again, mostly because of this, simple asalso youre mixing things up, bica works extremely well if testoterone is already suppressed and has almost no "SARM like activity" in low doses like 12.5mg to 25mg. the problem is bica monotherapy. not sure if youre saying mono while refering to estradiol monotherapy?
>>43119162>the problem is bica monotherapy. not sure if youre saying mono while refering to estradiol monotherapy?ohuhh, yeah, i meant estradiol monotherapy, hahahaokay, that makes more sense now, sorry for the confusion and rude interrogationi had a long post lined up to refute but we're on the same page, so it's a word mandala now, gone with the wind, with 20 scihub tabs left in its wake
>>43109152people who trust powers will always be cowards
>>43119835>NOOOOOOOOOOOOOO you can only trust endos who proscribe 1mg SPIRO its SAFER you COWARDS!!!!cry more spirohon
>>43119888
>>43119921>peta, you dont need to be feminine to be a woman peta, peta you are already a woman to me peta, a woman whos is da father of our children! now fuck me with your woman penis, peta!
>>43108936check the date
>>43120032based, it's about time some muckracking journos shine some light on pinkpillers shipping bathtub hormones to kids
>>43120032Wow, turns out this journalist wasnt actually being kind or caring, but wanted to cause harm, who knew
They're also on here btw>>>43119213and y'all keep giving away suppliers and their informants. Bunch. Of. Retards.
>>43117597no, it's this one. a jewish guy complaining about how his white privilege, but that he still has it better for being white than his black partner, but that his jewish ancestor helped black people so he is free of sin. she won a pulitzer for this. https://archive.nytimes.com/www.nytimes.com/library/national/race/061400harmon-net.html
>>43120294Some trans people just arent that smart
