So like what's the actual verdict on HRT and smoking tobacco? When it comes to any proper evidence, we have the chudscience "it raises your testosterone", we have the vague science "it ruins oral estradiol" (which in this case i'm doing injections), the unhelpful "IT GIVES YOU CANCER ZOMG", and then we have the anecdotal "it's really just genetics again." Yurotrannies tend to be hotter than burgertrannies despite their higher rates of tobacco-nicotine consumption by the last point.
>>43152707quote that i haven't at all factchecked that i found on the most reliable source in the world (reddit): "If I understand it correctly, it seems like nicotine gets converted to cotinine and metabolized in the liver (hepatic clearance), sharing same enzymes as estradiol. So then your estradiol gets faster clearance at first pass metabolism (gets broken up into less effective conjugated estrogens) and you get less of the juice to the bloodstream. Or something close to that."if this is true, this is probably why oral estrogen is affected while injections aren't, since nicotine only affects the absorption of estrogen into the bloodstream.
>>43152707Also Yurotrannies are hotter than burgertrannies because all Americans are fat retards with neanderthal intelligence, hope this helps
>>43152753now do injections mean subq or im
>>43152707nothing happensamericans are literally fucking insane and brainrotted by 900 years of cia propaganda dont listen to themdo what u want
>>43152707>it ruins oral estradiolreal>which in this case i'm doing injectionsok tru. it makes u bald. >IT GIVES YOU CANCER ZOMGwell it does. smoking is extra bad. but at least you didnt conflate and say nicotine gives u cancer. but it does make u bald. nicotine is a vasoconstricter and reduces oxygen flow to the upper layer of skin. means your face and arms and everywhere loses color turns all gray and ashy and wrinkly and saggy then your hair follicles shrivel up until they disappear and your hair falls out. the formaldehyde and benzene in burning tobacco probably has e similarly negative effects. also gives you acne and those creases next to your eyes/mouth>t. science knower who quit vaping
>>43152753if this is correct then sublingual/buccal shouldn't be affected right? i always thought that the deal with smoking was that the tar and stuff fucked up your like, cheek tissue's ability to absorb the E. like who tf actually cares about oral route stuff, nobody takes oral pills as prescribed you'd just be hondosing yourself for no reason>>43152764does that make any difference at all? i thought that the science and anecdotal evidence agreed on the fact that as long as you inject properly they're identical (except for undecyclate apparently)
>>43152707well the lack of evidence shouldn't encourage you to smoke, there is only one case to my knowledge in which smoking is beneficial (while still having all the negative side effects)don't find excuses to smoke, just because nobody feels like doing studies on tranners
>>43152759realbut seriously an european slop diet is wayy better than an american slop diet (which is every american diet because yall put high fructose corn syrup and presevatives and shit in fucking EVERYTHING), and it's not like most europeans don't exclusively eat slop, you can cook decent food for cheap
>>43154332hold on what's the one case in which smoking can have some benefits? I've never heard of this before(not gonna start smoking btw, I've tried taking a few puffs a couple of times and it always makes me feel nauseous and like I'm about to die for hours afterwards.. also i already have alcohol as my socially acceptable vice of choice)
>>43154370colitis ulcerosa
