I'm an aspiring neurobiologist that has managed to piece together theories that I fully believe are correct, and these theories will lead to Schizophrenia being "cured".I'm over the moon and excited about it, so I can't fucking stop thinking about it, and for that reason I want to discuss it with people!If you don't care or believe me that's fine, just call me delusional or ignore this post, but if you believe me or are at all curious, ask whatever questions you have and I'll elaborate on my theories and explain how I plan to go about "curing" Schizophrenia!
>>16782111>(pic unrelated)Is it tho?
>>16782116How would it be related? Are you implying I'm a delusional Schizophrenic and what I'm saying is a delusion?Or did I misunderstand?
>>16782111So is there a single mechanism or is it like cancer where there can be different pathways to the same result?
>>16782120It's like cancer.There are possibly dozens or hundreds of unique causes of Schizophrenia, and each unique cause requires a different unique treatment.This is why antipsychotics are so hit or miss, every antipsychotic works on a different mechanism, and since there are so many mechanisms that can cause the symptoms, medications won't always target the right things and alleviate symptoms.This is why some people are treatment resistant, while some only need 1 antipsychotic, and some require multiple antipsychotics.
>>16782126Interesting. Cancer is damage to DNA at a basic level, what kind of neuronal damage or malformation causes schizophrenia?
>>16782127There are dozens or possibly hundreds of different mechanisms that can cause Schizophrenia, but one of the common ones is "Receptor Dysfunction". That is, receptors in the brain, such as the Serotonin, Dopamine, or Glutamate receptors, are functioning incorrectly.So, at least one, if not many forms of Schizophrenia, are rooted in dysfunction of receptors in the brain.Unfortunately I'm passing out now and going to get some rest, but if this thread is somehow still alive when I wake I will continue to answer questions.
>>16782111>pic unrelatedYes it fucking is. Don't lie to us. If you were telling the truth, you wouldn't have used the image.
>>16782117>Are you implying I'm a delusional Schizophrenic and what I'm saying is a delusion?Perhaps
>>16782111not saying anything about if you should or shouldn't, but would messing with brain structure mess with the identity of said person?>but it's for the greater good of them and groupwell...this opens up doors. can be applied to psychos as well
>>16782363This theory applies to mental health as a whole. This will open up possibilities to permanently treat, and effectively "cure" dozens of mental illnesses. It's possible we'll also develop an ACTUAL cure for them one day, as it's possible that we can actually repair the underlying mechanisms responsible for said illnesses.It's possible that this would slightly alter the person's personality/personhood, so they would of course need to consent to it, but personality is super complex and not specific to one part of the brain, so it would never COMPLETELY change a person, only slightly if it ever does.
>>16782133How is it related? I know Lain is schizophrenic, so is that why it's related? I just like Lain and wasn't sure what image to use so I settled on posting her.If me liking her and her being schizo makes the pic related, then sure, I guess it is related somewhat.>>16782241Well, I know for certain I am delusional. I want to be schizophrenic when I'm unmedicated, but when on antipsychotics I don't want to be schizophrenic.So, it is GUARANTEED that I'm delusional, but this doesn't mean my ideas/theories on how to go about curing mental illness is also a delusion.I've talked to lots of knowledgeable people, therapists, doctors, psychiatrists. All of them agree with my ideas and theories, which leads me to believe I am not delusional about this, and in fact correct.
>>16782724It probably comes down to behavior that's bad for the society and at individual level, but even that is murky af. It can easily go wrong.Plus I'm not sure at this point, that having a society full of "healthy" people is desired. I think the real state of things is way darker than this, apart from the whole public narrative.
>>16782729LAIN IS NOT FUCKING SCHIZOPHRENICI HAVE A DSM RIGHT NEXT TO ME (even though it's not a diagnosis anymore) AND I KNOW FOR A FACT SHE ISN'T
>>16782738It would be unethical to force these treatments on someone that doesn't consent, it would be entirely unethical. However, in certain cases, it would be a better option than locking up the dangerous people for the rest of their life, or potentially killing them.>>16782741Okay, maybe I was wrong. I've definitely heard theories and people claim she is schizophrenic, I just assumed it was true, but she may not be.So how is Lain related to this if she's not schizophrenic?
>>16782778>However, in certain cases, it would be a better option than locking up the dangerous people for the rest of their life, or potentially killing them.I think you should read/watch A Clockwork Orange and you'll find this idea has been thoroughly considered.
>>16782111lmao gits chads stay winning, lainers stay whining. solipsists will literally never make it. op is in schizophrenic shamblesoh, and there are also serufu gigachads, these individuals shape all waifus with their dicks. shaping op like an onahole right now, not going to be easy for him
>>16782729>I just like lainYou were supposed to grow up to realize the first anime you liked was fucking shit.
>>16782130>this inheritable mental illness is.... caused by dysfunction of neurotransmitter receptors!wow anon, you're really blowing away the competition here
>>16782111I Managed to cure my schizophrenia. I had the Schizo-affective Manic type disorder.only thing i cant smoke weed and i rather have to avoid all drugs, alcohol in moderation is fine.i take my meds whenever i feel like it, with 3+ months of no meds at all.All that while traveling a ton with my car, did like 25k miles in the last 12 months, never had any car accident.have a remote IT job, currently a senior in my role, getting another job offer this month with a huge pay bump.play the stock market, i read and learn a fuck ton, have a gf from a rich family.if you manage to get your schizo under full control it gives you a kind of charm that is basically celebrity level type of charm.i get served outside the queue, get free stuff, free services at different places etc.It really is possible, it was tough as fuck and i actually did want to kill myself when i was a teenager.Now i have a mortage and life is just begining for me.
>>16782111>Posts LainYou didn't have to mention anything about schizophrenia, I already knew. At the very least try not to kill yourself.
>>16782962I never said this is new information.>>16782982You already knew what? What are you trying to say, I have absolutely no clue...
>>16782111Pic is definitely related. Lain is an archetypal schizoid / schizotypal.
>>16782729>I know Lain is schizophrenicWait, I thought she was a god? Or possibly a manifestation of the internet? Or both?
>>16782111You're retarded.
>>16783007Okay, sure, pic is related.>>16783008My interpretation is all of the above. She was schizophrenic but ended up becoming a god somehow.>>16783010What makes me retarded?
>>16782111It’s easy just sell your soul to heal
>>16783015>all of the aboveI think I get it. Her schizophrenic status made her disassociated from humanity, thus an ideal vessel for digital godhood.
>>16782111>>16782126>aspiring neurobiologist>but also so functionally illiterate and unable to grasp middle school level English, that I incorrectly use double line spacing AND paragraph breaks after every single sentencelelAlso>provides ZERO evidence of claims regarding "cure">>>/x/
>>16783096Yeah, that's about how I have interpreted the story of it.>>16783104It's just how I like to format my typing, what a weird thing to nitpick.As for the zero evidence, what specifically do you want me to provide evidence of?I will happily explain how we will go about curing them, and provide studies affirming my views.Just ask a question so I can specify, because there's TONS of different pieces of "proof", I just want to know which part specifically you would like me to prove.Do you just want a full explanation? I will happily provide one.
>>16782111i believe in drug psuchosis stone cold sober schizo is a lie
>>16782111The omniclamp is going to see you trying to cure schizophrenia, and clamp your cords. They clamp.
>>16783846I mean, it's proven that it can be genetic.There are some people that have never touched a drug in their life and still end up developing Schizophrenia, this proves it CAN be genetic. If you simply believe every single person in this camp is lying, then you're just being completely silly...You are correct that it can be drug induced, it is also sometimes permanent in this scenario, meaning even once you're sober you'd still experience psychosis until medicated with antipsychotics.>>16783929Good luck catching me, Omniclamp!
>thread posted nearly 2 days ago>OP has done nothing but attention whore
>>16782111>I'm going to "cure" SchizophreniaI see. You must be a PANTS enjoyer. https://www.ebi.ac.uk/interpro/entry/InterPro/IPR021475/
>>16784027Alright, fine, here's a massive wall of text to explain lots of the science behind it.It's very long so I will have to break it up into multiple messages.Explanation:There are multiple theories that are currently "proven and accepted" as the general consensus on the cause of Schizophrenia.There are three theories I am referring to, the "link between Schizophrenia and Substance Use", the "Glutamate and Dopamine Theory" and the "Antipsychotic Induced Dopamine Supersensitivity".I will give a brief explanation of these theories below, as well as a link to a single study that affirms these theories. I am only going to link a single study for each theory as they are well accepted by the scientific community, and finding other studies on the topics is very quickly done with a simple Google search. If you wish to get more in depth on the topics then you can do a simple Google search to find other studies to read and brush up on the theories mentioned.Before I move on to the explanations, one other "proven and accepted" theory that I don't have a specific study for is that treatment for Schizophrenia is complex because medications work differently on people with Schizophrenia, even if they share the same symptoms. Two people suffering from Schizophrenia could share identical symptoms but still respond differently to the same medications. We also know that some people have "treatment resistant" Schizophrenia, and that no currently available medications will help their symptoms. This will be important when explaining my theories, so it was necessary to explain here even though I don't have studies to link. A quick google search will bring up what I mean, so despite not having any specific studies, it's well accepted and easy to look into!
>>167840601.) Link Between Schizophrenia and Substance Use:This theory posits that those diagnosed with Schizophrenia and Psychotic Disorders should avoid drugs, especially those of a psychedelic nature, as using these drugs can temporarily and/or permanently worsen the psychotic symptoms.https://pmc.ncbi.nlm.nih.gov/articles/PMC6094954/2.) Glutamate and Dopamine Hypothesis:This theory posits that the underlying mechanism that causes Schizophrenia and it's symptoms is dysfunction of brain receptors.https://pmc.ncbi.nlm.nih.gov/articles/PMC6953551/3.) Antipsychotic Induced Dopamine Supersensitivity:This theory posits that some Schizophrenics experience "rebound psychosis" upon cessation of an antipsychotic medication, and that the cause of this is because long term use of antipsychotics both eliminates symptoms temporarily, while also worsening the neurological differences that cause Schizphrenic symptoms.https://www.sciencedirect.com/science/article/abs/pii/S0028390819301571My Theories:1.) Schizophrenia isn't just worsened by drug use, but it can be directly caused (gained) by long term drug use.As we know, psychotic symptoms are worsened by drugs. We also know that antipsychotics can worsen psychosis over time, despite the fact that it alleviates the symptoms while it's in your system. There are also some people living with Schizophrenia that fully believe they "gave themselves" Schizophrenia through long term drug use, but most doctors will say they're wrong. I believe these people are in fact correct, and that doctors are wrong and have misunderstood this phenomenon.
>>16784062Moving on, the reason drugs can worsen psychosis is the same reason antipsychotics worsen psychosis with long term use. This is a result of receptor dysfunction in the brain. The drugs, while in your system, correct the "dysfunction" of the receptors they target, this is why they get rid of psychotic symptoms. At the same time, after long term use and cessation of the antipsychotic, the individual in question will experience worsened psychosis. This is because while it corrects the dysfunction of the receptor, it also means the receptor is now functioning differently. Through this "different" receptor function, the brain tries to adapt, and over time it alters these receptors making them more dysfunctional, as the brain is relying on a drug to function correctly. The drug causes it to function correctly, but because of neuroplasticity and how the brain adapts, it also ends up changing your brain chemistry over time, which worsens the underlying dysfunction, leading to worsened symptoms when medications are finally stopped.2.) Receptor Dysfunction not only causes Schizophrenia, but also many other Mental Illnesses.As we know, there are "comorbidities", that is, mental illnesses that are seen more often in the same individuals than they are separately. This is incredibly common and seen among dozens of mental illnesses, which suggest they share an underlying mechanism. We know that receptor dysfunction causes psychotic symptoms, and that some other mental illnesses are more common among those with Schizophrenia. This suggests that the underlying dysfunction that causes Schizophrenia is also the same underlying cause for some other illnesses that are "comorbid" with Schizophrenia. It's likely that many other illnesses such as ODC, Delusional Disorders, and possibly even Dementia/Alzheimers share some of the same mechanisms, and would be partially treatable similar to how Schizophrenia is treated, with antipsychotics.
>>167840633.) Schizophrenia has Dozens or Hundreds of "Subtypes" that should be individually classified to improve treatment of the disease. Doctors moving away from classifying Schizophrenia into subtypes has done more harm than good, and we should work on bringing that concept back. It's likely that Delusional Disorders, OCD, and possibly other Mental Illnesses are effectively "subtypes" of Schizophrenia, as they share at least 1 underlying mechanism:"As previously explained, Schizophrenia is caused by receptor dysfunction. The accepted theories talk about dysfunction of multiple receptors all contributing to Schizophrenia, but I have a related but different theory. There are potentially dozens or hundreds of different receptors that can cause psychotic symptoms, and in some cases only one type of receptor is experiencing dysfunction. This is why I say there are dozens or hundreds of subtypes of Schizophrenia.Two people experiencing Schizophrenia with the same symptoms, their symptoms could be a result of dysfunction from completely different receptors. Someone experiencing hallucinations might have dysfunction of their Serotonin receptors, while another person with these symptoms instead has dysfunction of their Dopamine receptors. So my theory posits that there are potentially dozens or hundreds of subtypes of Schizophrenia, because there are potentially hundreds of different receptors that can cause these symptoms.This theory is affirmed by the fact that antipsychotics are so hit or miss, the fact that some people need multiple antipsychotics, and the fact that sometimes people are entirely treatment resistant.People only needing 1 antipsychotic, there already exists a medication that works on the receptors causing this persons Schizophrenia.
>>16784065People needing multiple antipsychotics have dysfunction of multiple receptors, and until all of them are treated then the symptoms persist. So unless we find a medication targeting all of their dysfunctional receptors, they made need multiple drugs that work individually on each the many different receptors that are dysfunctional.People that are entirely treatment resistant, we just haven't found a medication that targets their dysfunctional receptors yet. So we just need to keep discovering and studying more drugs until we find some that target the receptors of the person that is "treatment resistant". So it's possible, and likely, that one day we will have identified every cause of all subtypes of Schizophrenia, and will have developed drugs that target only those receptors, leading to "perfected" treatment, allowing us to eliminate all symptoms, effectively curing them, just with a requirement of lifetime treatment with medication.TL:DR;Lots of mental illnesses share an underlying mechanism, an example being dysfunction of the Dopamine receptors in the brain. We will soon develop the technology to single out these "underlying causes" via scans of the brain. From there we go immediately to specific medications that target that unique underlying cause, meaning no one will need to potentially try multiple or even dozens of different medications to find one that works (if any do). We simply scan their brain, then we already know which meds will work for them based on which ones directly work on the underlying mechanism causing their symptoms, assuming we have a medication that does target the cause of their disease.This is the route to curing mental illness. I'm not saying it will happen tomorrow, or even in the next ten years, but once we develop the technology to single out the causes of the disease, then we can directly treat the cause, assuming we have a medication that works on it.
>>16784066So basically, we need to start developing brain scans that can single out specific brain receptors and things that can be causes of mental illness.Once we have this technology we can do targeted treatment that will be effective *the first time* instead of taking multiple or even dozens of attempts to treat the person in question.Again, we don't have this technology yet, but once we do, mental illness will effectively be "cured", and not even just Schizophrenia, but MOST mental illness will be treatable to the point of being effectively "cured".It's also possible one day we will discover drugs that repair the damaged parts of the brain that cause symptoms. This is even further off in the future, but it means there's a possibility we could actually FULLY cure most, if not all mental illnesses.
>>16784069Are you talking about electroshock therapy?
>>16784069I could waste my time trying to make you realilze and admit that you've not read even 0.01% of all the scientific literature relevant to this, but then again, you will never act on your dreams so it doesn't matter if your hypotheses don't align with reality.
>>16784484No, not to my understanding. I don't know much about electroshock therapy aside from the basics, but my hunch is that it's just a form of abuse still accepted by the medical community as a form of treatment, because it makes the ill person more docile and easy to deal with for other people, or society as a whole.It's possible electroshock does actually help alleviate some symptoms, so it's possible it COULD be a potentially helpful form of treatment, but my gut feeling is that electroshock therapy is like lobotomies, something that's been accepted because it makes dealing with the ill patient easier for society.If electroshock therapy does actually target some of these underlying mechanisms, it is possible it is a helpful treatment for SOME people, but my gut feeling is electroshock is just a legal form of abuse still accepted by the medical community.I'm mostly referring to medications, but it's likely some forms of therapy like talk therapy (and possibly electroshock) will be the ideal treatment for SOME people with mental illness, but even if that's true a majority of the time it probably worsens peoples symptoms, as it's targeting the wrong part of the brain (in most patients, but not all patients).>>16784492I know I haven't even read 0.01% of all scientific literature, but that doesn't mean I'm wrong. All the literature I've provided, and every single piece I've ever read and studied, directly affirms all my theories on how we can cure mental illness.Do you have any evidence disproving my theories, or do you just not believe me? I've provided lots of evidence for you to look into, so if you don't want to believe me that's your choice, but it doesn't make me wrong.
