Earlier this month, a huge team of stem cell researchers dropped a very significant paper identifying Glutathione S Transferase Alpha 4 induction as the primary mechanism by which OSK reprogramming rejuvenates cells... >Reprogramming Factors Activate a Non-Canonical Oxidative Resilience Pathway That Can Rejuvenate RPEs and Restore Vision>https://www.biorxiv.org/content/10.1101/2025.08.30.673239v1.abstract>GSTA4 overexpression alone enhances mitochondrial resilience, rejuvenates the aged RPE transcriptome, and reverses visual decline. GSTA4 is consistently upregulated across diverse lifespan-extending interventions suggesting a broader pro-longevity role. These findings uncover a previously unrecognized protective axis driven by Yamanaka factors that circumvents reprogramming, providing therapeutic insights for age-related diseases.Soooo... is DWS's protocol fully deprecated at this point? Just cycle various GSTA4 inducers? Are there some other chemoresistance enzymes out there too that you should just cyclically jack the fuck up, unless you're a cancer patient on chemo?>CAPTCHA:40W0WW
