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File: lizard-guy.jpg (100 KB, 680x557)
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are DNA companies a scientific scam?
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>>16804305
DNA ancestry companies are not paid to determine the species of the sample but the closest match to humans. They do this by looking for specific short sequences and their relative frequency. It's like if a service existed that identified car colors from a spec of paint, they will always respond back to you with a color of a car no matter where the actual paint came from because red house paint appears as if came from a red car the same way the most prominent AATTCG line indicates a Mongolian even if came from a whale.
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>>16804305
Huge numbers of false paternity have been discovered by those services. Be wary if your wife gets very uncomfortable when the subject of services like 23andMe comes up.
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>>16804346
Yea true it’s just a statistical analysis relative to other data. They even state it can be wrong.

Paternity test have been known to be wrong
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>>16804346
Every single biochemical test in the world has a control to verify if you're actually testing the right thing. It's trivial to check if a sample comes from a human.
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>>16804305
He's a lizard
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>>16804305
>Lizard DNA
>51% Ashkenazi Jew
Dunno man, seems pretty accurate to me.
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>>16804942
i thought they were neanderthals, not lizards
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>>16804942
The 48% Chinese was an error though. That was just the result of contamination in the saliva from bugs the lizard had eaten
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>>16805248
do you think china is in west asia?
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>>16804877
Why? The company assumes in good faith that their human ancestry test only has inputs that consists of human samples. The fact that you can "trick" them is totally irrelevant.
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>>16805250
Anywhere in Asia is China as far as I’m concerned
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>>16804305
>for $100 we will use our collection of random mutt DNA to reverse engineer your ethnicity
Sounds legit.
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I am no expert, however, given how much genetic similarity we have with drosophila, primates, etc., likely the bioinformatics just did a query on the genome sample, found a couple strands which match with Jew/Iranian DNA, and called it a day.

Surprised they didn't notice something off when they measured the genome length. Maybe it is a fabrication?
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>>16805589
>I'm a drosophila
Kys then.
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>>16805594
It's the 2~3% difference in gene that matters, much like how the 0.01% difference between you and a nog determine the IQ difference. Or are you a nog yourself?
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>>16805597
>I'm a retard but my parents were 0.01% less retarded
Nog away.
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>>16805599
I don't get the central point. You don't like having overlapping genes with the drosophila? You think humans are so special to create an entire new way of biological survival independent from all other life? lol no
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>lizard people are jews
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>>16805602
We can organize social norms, together, around how people react to it without being influenced by how fruit flies react to it.
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>>16805610
Are you a devout Christian?
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>>16805611
Answer both ways and I'll choose my adventure.
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>>16805615
When God designed organisms there was no guarantee he would have made a unique set of genes for each of us. DNA/RNA/protein system is like the game engine, and each of us are like the games built atop it. Of course there will be overlap.

Or for the evolutionary path, if there is a universal common ancestor, of course there will be overlap as we diverged from it.
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>>16805617
>I am no expert, however, given how much genetic similarity we have with drosophila, primates, etc.,
These are your words.
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>>16805623
Yes, there is a large overlap in genes, and within those overlapping genes one might find genetic parts similar to Jews by coincidence. No, I am no expert, but you don't need to be an expert to know this.
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>>16805626
You literally said you have a racial affinity to fruit flies and a monkeys.
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>>16805628
https://www.mpg.de/10973625/why-do-scientists-investigate-fruit-flies
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>>16805632
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>>16805254
>The company assumes in good faith that their human ancestry test only has inputs that consists of human samples.
This is not how it's done in the industry. You have control not only to check if it came from a human, but also if it's saliva and not piss etc.
This saves a lot of money by not running expensive tests on bad samples.
Also the story is fake, you retard.
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>>16805775
Customers pre-pay so the company already received the money for the testing. Adding a human check to the pipeline to weed out the one in ten million times someone submits non-human DNA so they can save on the full test of that one in ten million edge case doesn't save money, it adds a huge amount of expense.
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>>16804305
These tests are not done using sequencing (which would clearly show what species the DNA came from), as sequencing, even with the next gen sequencers like the nanopore systems, is far, far more expensive than the qPCR RNP or SNP analysis method, and is far more time consuming.
So the method used is the above mentioned polymorphism comparison method.
Take the whole genome. Look at areas where it often differs between samples (repeats or single nucleotide differences). See if these differences are characteristic of groups of people. Find the ones that are. Make PCR primers for each group specific marker. If the group specific marker is present, PCR will amplify. If not, it won't.
Now all you have to do is take a sample, isolate DNA (this is a 1 hour process with an automated machine like an EZ-1), add a PCR master mix and a primer mix containing primers for all group specific sequences, and pop it all in a qPCR. Run it for 30 cycles or so, an in 2-3 hours you are done. The whole thing took half a day compared to sequencing which would have taken several. See which regions amplified to what extent in what combination and you know your ancestry.
Here is the thing. We share around 60-75% of our coding regions with lizzards. That is 17000 genes. Clearly some of the primers designed for polymorphisms in those genes will annele and end up amplifying. Especially if it is RNP analysis, RNPs are some imes found in the same places across species.
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>>16805254
>The company assumes in good faith that their human ancestry test only has inputs that consists of human samples
But such a thing is impossible given one's saliva contains bacteria.
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>>16804305
They are pretty accurate. I got gifted a 23andme kit while I was in Netherlands by a friend. I am not Dutch. The kit accurately guessed my ethnic background and even showed me from which provinces the influence is coming from. My country is on the other side of the world and in general my country has no historical encounter or culture exchange with Netherlands. There has not been large scale DNA exchange. My friend ordered from his account. He is a dutch native and has never been to my country. My name or any information about me wasn't registered anywhere. The only thing 23andme got from me was a vial of saliva. Yet it predicted it surprisingly accurately. So yes they work.
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>>16804305

Idk about you, but Jewish lizards sound realistic enough for me.
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>>16804305
They're "scams" in the sense that they aren't doing full genome sequencing which is what you'd want. They're just finding SNPs which is like hashing a 1 GB file into 10 characters.
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im trans by the way not sure that matters
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>>16804942
SHUT IT DOWN!!!

https://m.youtube.com/watch?v=gujPXF1WLKI



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