Insulin resistance is when cells don't want to uptake glucose from blood. But can it actually be good for health and longevity since glucose is a highly reactive, toxic compound influx of which into the cells causes glycation and suboptimal functioning of cellular machinery?Retarded doctors use insulin to manage type 2 diabetes because they think lowering blood glucose by any means necessary is good, but actually insulin resistance is an adaptive mechanism protective for the cells during systemic overload of energetic substrate, and they do way more harm than good with this practice.
>>16952384Perhaps the population is dysgenic; all these seemingly bad adaptations have not been selected for due to some obscure benefit and are simply a product of accumulating mutation unchecked by harsh Darwinian pressures that are currently restrained by complex civilization.This is civilizations collapse. Civilization allows dysgenic breeding; eventually people are too stupid and ill to keep things running.
>>16952384Are you retarded or somethingDo you not understand that high blood sugar is what drives glycation?
>>16952405>Do you not understand that high blood sugar is what drives glycation?If you increase insulin sensitivity all you do is relocate this sugar from blood to cells. You decrease vascular glycation at price of increasing glycation in organs. You skipped biochem.
>>16952407Blood stores glucoseCells process it into other things like ATP and glycogen. I don't know the numbers but the burden of proof is on you to proof that intracellular concentrations of glucose ever come anywhere near blood levels, let alone stay that way for hours like they do with insulin resistance Are you just having a schizo episode because you got diagnosed with diabetes? Be honest
>>16952404They eat McD's every day. It's THAT simple.
>>16952409>Cells process it into other things like ATP and glycogen.Which generates many glycating chemicals, like methylglyoxal... Read following papers regarding glycation and insulin resistance:>An overview on glycation: molecular mechanisms, impact on proteins, pathogenesis, and inhibitionhttps://link.springer.com/article/10.1007/s12551-024-01188-4>Insulin Resistance as a Physiological Defense Against Metabolic Stress: Implications for the Management of Subsets of Type 2 Diabeteshttps://pmc.ncbi.nlm.nih.gov/articles/PMC4338588/>Are you just having a schizo episode because you got diagnosed with diabetes?No, i don't have diabetes because my physical activity level is very high and i don't have much visceral fat. Just scientific curiosity.
>>16952422Interesting But the takeaway seems to be that it's best to manage diabetes by restoring insulin sensitivity naturally through exercise and fasting, which has always been my and I'm sure many others gut instinctIt's not like high blood sugar doesn't come with its own set of risks, that shit will make your arteries pop
>>16952384insulin resistance doesn't exist, it's just misnamed
>>16952384type 2 is due to bad covid infections retard
If you're resistant the sugar is going to damage your blood vessels by just sitting there. If there's excess fat and sugar in the blood the sugar is stored first.
>>16952384Nigger, cells need glucose for the Krebs cycle and to make acetylcholine.
>>16952572So keto causes dementia?
>>16952594No, dementia causes keto
>>16952594No, why would it? The body synthesizes glucose even if you're not ingesting it.
So what does it mean if you have hyperinsulinemia?
>>16952409this> t. 108 FSIQ anti memer
>>16952680from muscle right?
