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Let's say they Thragg has a catastrophic defect on allele 1 and Anissa has a catastrophic defect on allele 2. They go on to have kids, 25% of which will have defect 1, 25 % of which will have defect 2, 25% of which will have both, and 25% of which will have neither. Suppose that these children have kids with each other. How can we organize the incestuous breeding of these siblings so that we can find, with high confidence, individuals with neither defective allele?
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>>16960451
Who?
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Realistically they would be able to bioengineer their way out of this issue. They have advanced technology, so they ought to be able to extract genes out of corpses and introduce them into living Viltrumites for extra diversity, or even simpler create clones of said dead.
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>>16960451
You're presuming they so genetically weak to begin with. They're likely not.
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>>16960451
>How can we organize the incestuous breeding of these siblings so that we can find, with high confidence, individuals with neither defective allele?
If each woman birthed 20-30 kids you're gonna have an easier time of it.
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>>16960521
if a genome can be stored in a text file, what is to stop an advanced society from creating genes in the labs? why do they need to "extract" genes from dead tissue? i am sure the Viltrumites genetically profiled their entire race at some point.
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>>16960451
Couple of quick questions
Why are Thragg & Anissa the only founding population available?
Are you trying to eliminate all copies of alleles 1&2 from the population?
What working population size are you dealing with?

If the option is available I feel like embro selection is the quicker and more reliable way to start but if you want to do it old school I guess that's what you'll work with.
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>Viltrumites are arch-eugenicists
>Rather than simply engineering their children with ideal genetics and raising them in a set of proven ideal outcome methods, they have Hunger Games

I think these guys might be fuckin stupid, guys.
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I asked a simplified version of the actual scenario:
Assuming that there is a founding population of 25 adult male Viltrumites and 25 adult female Viltrumites, each with a fertility window in the multiple 1000s of years, 18 years until the age of adulthood, a gestation period of 9 months, and none of whom are suffering from a genetic disorder, how can selective breeding be utilized to ensure that all catastrophically defective alleles are bred out of the population. Assume that tools like genetic screening, embryo selection, and gene editing are unavailable, and that the only tools available are selective breeding and culling.

>>16960690
In the simplified scenario, we're just starting with a population of 2, and just trying to eliminate the 2 defective alleles. However, if you think it's more effective to introduce a third or fourth Viltrumite into the mix, then go ahead. Each new Viltrumite you introduce will have a unique defective allele.

>>16960605
That's what I figured. After 3-4 generations of siblings and cousins mating, it'd be pretty easy to determine who didn't get the recessive defective alleles
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I just simulationfagged it. The first 2 viltrumites keep having kids until there's at least 50 males and 50 females, then each possible pair in the next generation has kids until they have they have 20 kids, or a retard, whichever comes first. If they have a retard, those 2 are removed from their generatons breeding pool. The retards siblings and cousins are then also removed from the breeding pool. In the end, a little under half of the first generation is removed from the breeding pool. Of those remaining in the first generation, a little over half carry a recessive allele. The second generation breeding pool averages ~1000, and about a third of them carry a recessive allele. The whole process takes about 800 years, which is definitely doable for viltrumites.
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>>16960946
>The first 2 viltrumites keep having kids until there's at least 50 males and 50 females
How long is their fertile window?
what's their theoretical maximum number of pregnancies? Are multiple births common?
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>>16960995
>How long is their fertile window
At least a thousand years
>Max pregnancies
Thousands
>Are multiple births common?
I don't think so
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>>16960997
If that's the case and they're not strictly monogamous there's a lot of room for back crossing onto the original parents.
you could create someone who's near enough a genderswapped version of the original parent.

It might be best to run the system as semi isolated pools, introductions from other pools should go through a quarantine screening phase in a sub pool before introduction to the root pool.
Bigger numbers are better.
It might be easier to back cross a line that only has one of the genes, purge out their respective defect then recombine the two lines

Are you just trying to completely eliminate the two defective alleles? you'll want to maintain known carriers like the two founders to test for their presence.
Feels kind of wasteful to not be selecting for general fitness if you're going to all this effort
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The only possible solutions would be clones and genetic engineering. The comic proposes they use humans but we know that a VIltrum-human hybrid is 99% Viltrumite, so they're going to be a 99% identical copy of their parents, solving no issues. And the 1% left over is uselss human DNA, which after several generations of reproducing with humans will have built up until all Viltrumies are substantially weaker.
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>>16961000
I Forgot to mention that 50% of all offspring get purged for not being peak warrior specimens
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Wow Invincible must have next to no fanart if you have to resort to thirsting for extremely low quality AI “art” like this
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>>16961038
It's an ugly art style



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