Piquen means sting in one of the romance languages, can't remember which. Vespidae is the wasp family, so its stinging wasp just mashed together as a name.

Which is fucking retarded, because she's a bee, and Beedrill, who is modeled after a Yellow Jacket, is really a wasp, but this is Gamefreak we're talking about and they love to put in turbo retarded stuff like 'this pokemon burns at 143542352364523627 degrees Celsius' so don't expect intelligence.

The Japanese name was just ビークイーン
with the second ー removed. Beequen was probably still considered too generic.

>>58779410
Wasperain and Beeherum