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Since we don't seem to have any threads on it, post your favorite supplements that purport to somehow combat a maybe disease known as "aging" or "hitting the wall" or whatever.

>inb4 nothing works, Bryan Johnson looks 90.

Glycine and N-acetyl-cysteine actually went through a HUMAN clinical trial a couple years ago showing they indeed do shit: https://www.bcm.edu/news/glynac-supplementation-reverses-aging-hallmarks-in-aging-humans

I think there's a pretty decent consensus that methylene blue and astaxanthin also do shit too. I recently started on a few grams a day of chokeberry and blackcurrant powders, thoughts on those?

What kinda pills are /fit/'s elite reaper cheaters poppin'?
>>
>>75607528
Dunning-Kruger Effect - The Thread
>>
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Not trying to defy aging just attempting to survive alcoholism

It killed both my grandfathers and has come close to killing me too many times

>fish oil
>k2+mk7
>NAC
>Milk thistle
>Magnesium complex
>Multivitamin
>Nootropic meme pills
>Folate
>Nattokinase
>Serrapeptase
>>
i dont fuckin care about looking perma 25 i just dont want to be the guy at 70 using a walking crutch or be one tiny fall away from a shattered hip
>>
sunscreen and quality sleep mogs any supplement
>>
Astaxanthin, hyaluronic acid pills, ecgc, TMG, glycine are all worth looking into as well as >>75607562
maybe add in TUDCA for your liver stack anon
>>
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>>75607562
ur missing this shit

>https://www.sciencedirect.com/science/article/abs/pii/S2210803323001732

>>75607568
zinc oxide shit only, the benzones are tranny-screen. also, uh...
>anon doesn't know many supplements improve sleep quality and/or reduce sleep requirements
>>
I just bought powdered nac, when I open it my eyes and nose and throat itch like crazy.
I bought it so that I could mix the nac with glycine and take them together - can I do this?
>>
>>75607562
For the record when I do binge drink and go off my nutrition/exercise regiment it only takes a couple weeks for me to start to have significant alcohol related problems, liver hands, jaundice, chest pains, fatigue, shaking, sweating, psychosis, extreme blood pressure, I feel like ive probably had some mini strokes and mini heart attacks in my life.

I am 30, and yes I drank multiple times more than you could imagine over the last 15 years.

This stack, in addition to sobriety and literal hours of cardio every day and my organs recover like 95%

Hope I never drink again
>>
>>75607597
>>75607598
Nice will look into it thanks bros
>>
>>75607598
>pde5 inhibitor in overpriced bottle

ginger root is 1/10th the price for 200% more PDE5 newfag.
>>
>>75607528
Primary focus should be to preserve your brain.
For that:
Aerobic exercises.
Cardio.
Keep free radicals low
Try to slow down your metabolism (can be achieved by fasting and the such)

Avoid hormonal deficiencies:
For women that means maintaining their e levels high even after menopause. The connection between cognitive decline and absence of sexual hormones is established (dementia)
For men it has not yet been linked (less research) however it is a fact that men with lower T levels have higher risk of dementia.
There's likely a time window for the action of these substances.
Besides that, NAC is indeed promising, but also a vast array of other substances.
Ultimately one may try to sum them all up together, however you'll never be 100% sure which one helped and which one didn't.
A wiki should definitely be compiled.
Bummer clinical trials on humans are so regulated.
>>
Methylene blue sounds good
>>
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Here ya go OP
>>
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>>75607636
>While the extent of age deceleration consistently increased with advancing age, mature castrates were on average epigenetically 3.1 months 'younger' than their chronological age (Figure 3B).

>Moreover, while early-life castration has been shown to extend human lifespan, androgen depletion in elderly men can be associated with poor health (Araujo et al., 2011).

Nice try, Bryan[na] Johnson. Still not buying your "non-feminizing estrogen."
>>
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>>75607562
all drinkers need to know about dihydromyricetin - aka DHM. I'm not exaggerating, this stuff is a silver bullet in hangover prevention. It's extracted from some Japanese raisin tree or some shit. Last year, my brother and I went on a weeklong bender from Christmas to New Years, and this stuff saved our ass.

For every 3 drinks, you take one 300mg capsule before bed. So if you have 12 drinks, take 4 capsules and chug a gatorade.

I'm serious though, it is legit. I encourage you to try out DHM on its own without the other hangover preventions (milk thistle, prickly pear etc.), just so you can see how powerful it is on its own. And then you can add the other back stuff in
>>
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>>75607528
>>
>>75607618
antioxidants?
>>
>>75607597
i tried astaxanthin once to see if it would prevent sunburn in summer, but it unironically kills your dick, probably because of it lowering DHT but also something about it reduces bloodflow to your dick. also it can give you that carrot tan eventually.
>>
>>75607756
all fucking berries are overcontaminated with carcinogenic pesticides, better to go hard on the pineapple, kiwis and maybe oranges/mandarins.
>>
>>75607760
>>
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>>75607760

this is how you can tell something is legit when you see fag niggers posting bullshit like this
>>
>>75607784
i didn't say it isn't "legit" for whatever purpose you want it to be, it seems to be a natural substitute for finasteride and prevents sunburn, who knows what it does antioxidant-wise, but its known to potentially cause ED. learn to google retard.
>>
>>75607791
If you are "afraid" of ED it means you are a beta, only betas get broken dicks.
>>
>>75607800
>you got predicted side effects from this biochemical reaction observed to happen in this process? why didn't you just make it not happen?
this board is sub 70 iq these days.
>>
>>75607800
why don't you blast tren and just think away the side effects? better yet just willpower yourself to godhood
>>
>>75607800
>>75607791
I'm so confused, should I use that shit or not?
>>
>>75607813
i wouldn't say take it or not, its not like it gave me some severe ED that persisted or something, but while i took it i didn't really feel anything besides that noticable lowered libido and slight limpdick.
there are a lot of studies on it talking about how its X times stronger than vitamin c and so on. but i personally didn't feel anything. i took 16mg/day.
>>
>>75607813
>>75607806
>>75607802
Look, your body knows it is weak and frail and that is why your body decided to make you concerned. Aka you are a beta

My body knows I am strong so my body does not force my brain to have such concerns, it would be a waste of time

Being a beta is in many ways a form of protection, your body knows you cant handle it, and so you build your thoughts around that

Dumb fags
>>
>>75607824
what i mean is, its up to you.
>>75607825
i took it and noticed the effect and quit taking it and the effect went away, i never mentioned any feeling about it, you're clearly a retarded dravidian out of his depth and should go back to whatever site you came crawling out of.
>>
>>75607831
Nah you're definitely a pussy I'm in my 30s and no amount of abuse of any substance has ever robbed me of rock hard boners

You would literally die attempting to keep up with me in anything
>>
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>>75607847
ok
>>
>>75607851

Please understand that a great proportion of what happens to you is in the reverse order, where your subconscious facilitates the conscious experience.

Not a single thing you find disgusting is disgusting for logical reasons, what happens is you get the emotional subconscious response and then you rationalize it after it has occurred within you. But you are absolutely convinced you have an opinion.

Just throw humans away entirely, really.
>>
>>75607528
just antioxidant max and polyphenol max
>>
>>75607877
things have side effects
i doubt astaxanthin can cause ED but finasteride can in very rare instances mess with your hormone levels and cause lasting damage.
>>
>>75607926
"Things have side effects"

Only if you are weak*

Effects of any type do not occur until your body cannot withstand it, if your body could withstand it, there would be no effect.
>>
>>75607877
>Not a single thing you find disgusting is disgusting for logical reasons

no, there is actually a lot of research on disgust reactions specifically tying them to visual signs of potential infectious disease.
>>
>>75607938
>if your body could withstant it
can your body withstand aids? then stfu
>>
>>75607994
uh, anon... there are actually are people who can: https://en.wikipedia.org/wiki/Innate_resistance_to_HIV
>>
>>75607528
I recommend you save money. That science is a bunch of nonsense. You can improve lots of "hallmarks" of aging without affecting aging at all, a hallmark of aging is having gray/white hair - that doesn't mean dyeing your hair black will make you a lot younger. That's essentially how the "anti-aging" industry works.

I would recommend avoiding accidents, avoiding extreme lifestyles or stunts, getting your basic nutrition, and that's basically all you can do.

You ever thought of overcoming death completely? It will never happen, but humans constantly feel a flawed "if only" that it could somehow happen, I've felt that as well. The same goes for these supplements. Calcium, vitamin d, MAYBE collagen are all you should be taking. If you're a real kook - vitamin c and a multivitamin. Other than that forget it.
>>
>>75608033
2/2 I forgot creatine* of course creatine. And whey but that's not really counted as a supplement. I won't judge you if you take another plant extract or two for some purpose, but definitely don't expect it to combat aging.
>>
>>75608005
ok but you aint one of them
>>
>>75608033
bla bla bla cope because you a faggot / broke / retarded
>>
>>75608033
>>75608035
this literally sounds like 1990s doctor speak. not even CoQ10? lmao. i swear, some people are waiting for the billion-person double-blinded century-long mortality study before they think antiaging therapy is a real thing.
>>
>>75608067
hes just really low IQ or already over 40 and bald
>>
>>75607528
>>>/x/
>>>/b/
>>>/fa/
>>
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>>75608113
>not >>>/sci/
>>
>>75607568
>sunscreen
Avoiding sunlight entirely will make you age worse, particularly sunrise/sunset sunlight (when red light is high).
>>
>>75607760
Total placebo mate, it won't 'kill your dick'? More likely it would do the opposite considering it increases testosterone.
It will reduce oxidative stress and inflammation which will more than likely extend ones life.
>>75608033
shutup brokie
>>
is NAD+ a meme? any recs on brands like life extensions?
>>
>>75607717
>>75607610

Jesus. Just do GHB if you really have to.
Fuck Alcojew
>>
>>75607765
agreed, always avoid fruits that you can't/won't peel. the amount of shit that gets sprayed on it doesn't just get rinsed away with some water
>>
>>75607550
That's not how you use that phrase.
>>
>>75608764
If it was water soluble to begin with it means it would likely already be in the fruit because it washes off into the soil then is absorbed by the roots and in every moisture binding part of the plant namely the fruit. Still ain't peeling kiwis the metallic tasting rind is the best part.
>>
>>75608156
redlight is a meme
>>75607598
>needing supplements to do what your body already does, sleep
could never be me
>>
>>75607528
Eat skin and your skin will be healthier. Chicken skin, the skin around eggs under the shell, and bone broth. All natural sources of collagen that made my crows feet go away. Basically got rid of all my wrinkles and I look 5-10 years younger than I did. I don't trust collagen supplements, they add inert powder to supps to save money so might as well eat the real thing.
>>
>>75608899
I think maybe sardines too since the skin is on them. Skin has what your skin needs, muscle has what your muscles need, and luckil
>>
>>75608900
*luckily we have milk otherwise we'd need to gnaw at bones like animals do.
>>
>>75608904
Eh calcium is one of the few things we can actually get really easily from plant sources. Zinc content might be an argument for bones though. Collagen skin and almost everything else. Fish have selenium too though so there's just that little bit extra something.
>>
>>75607550
The OP didn't exhibit any signs of overconfidence in their position which is a prerequisite for peak dunning-kruger effect ("peak" is part of the term btw).
>>
>>75607528
Luck out and get Celiac disease so your body doesn't get the nutrients it needs to develop.
Do a lof of fasting. The more food goes in, the more mileage you put your body through digesting it.
Sit in a dark room. This stimulates your pineal gland so you produce more melatonin. Melatonin increases HGH production.
Sunscreen
No alchohol
Don't take anything! no pills! nadda.
>>
>>75607528
Green tea & saw palmetto, this combo is natures finasteride. Works almost as good with none of the dick shriveling side effects.
>>
>>75608899
collagen peptides are significantly more bioavailable than any of that
>>
>>75609298
Tell me in your own words what you think a peptide is that differs from collagen
>>
>>75607564
>i dont fuckin care about looking perma 25
Yes you do you fucking retard. Everybody does.
>>
>>75609324
collagen is the raw molecule
hydrolyzed collagen is split into several very small strains with easily attach to the relevant receptors and trigger collagen production.

you can literally ask chatgpt it will tell you the same thing: peptides are much better
>>
>>75607624
> (can be achieved by fasting and the such)
Wrong. Only total cals matter not distribution
>>
https://www.sciencealert.com/surprise-hair-loss-breakthrough-a-sugar-gel-triggers-robust-regrowth
>>
>>75609370
Why would that matter if it's going to be cleaved at same fragile bonds anyway in digestion?
>>
>>75609370
>Bioavailable
>>
>>75609734
>>75609766
>>
>>75609766
Nonsense word for the most part. In this instance I'm guessing it just means partially broken down by enzymes or a weak acid which happens at multiple stages of digestion anyway. Just eat organ means and skin you big pussy.
>>
>>75607610
sounds like your liver is damaged from steroid abuse.
>>
>>75608764
you can take my organic raspberries out of my cold dead hands commie
>>
>>75608326
it lowers DHT
>>
>>75609906
what if I'm already on finasteride? is it pointless then?

I already look great for my age at 29, but I just use basic skincare (kiehl's facewash and "facial fuel" face cream) and take collagen and multivitamin. Plus finasteride like I said. People say I look early-mid 20s all the time. People are always surprised that I'm as old as I am.

I did lose some weight recently and develop nasolabial folds but other than that I think I'm doing well.
>>
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>>75609939
oh I also use green tea under-eye patches as well. those things are the ultimate hack for dark under eyes. under-eye cream doesn't do jack shit for me but those things do.
>>
>>75609543
>/fit/ ignored this
>>
>>75609885
never done steroids

lots and lots and lots of alcohol anon
>>
I'm just popping in after all these replies to remind everyone here that no long-lived person took any of these garbage meme supplements that you've been conned into buying. Ironically, the one thing all long-lived people have in common is the opposite of obsessing about these minutiae.
>>
>>75610134
impressive
>>
>>75607618
punicalagin, ellagic acid> urolithin A has a lot more impacts than only pde5 retard
>>
>>75607528
eat the foods to make sure you got all the cofactors
strawberry -fisetin
blueberry- pterostilbene
pomegranate -urolithin a
broccoli sprout - sulforaphane
red onion -quercetin
wheat germ -spermidine
greentea - egcc
parsley -apigenin
>>
>>75610382
What do these do
>>
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the only real one comin' through
>>
>>75608899
>I don't trust collagen supplements, they add inert powder to supps to save money so might as well eat the real thing.
Just find a trustworthy brand. NSF-approved brands may meet your standards.

>>75608904
>otherwise we'd need to gnaw at bones like animals do.
You speak as if practically everyone tolerates milk and milk has been how humans mainly met their Ca needs historically. No, bones was how. If they weren't edible whole, we'd consume them powdered.
>>
>>75609245
>with none of the dick shriveling side effects.
Has it been studied as well as finasteride? If that combo reduces blood DHT, I don't see why it wouldn't have the same side effects.
>>
>>75610382
egcc is better supplied seperately you wouild need to drink copious amounts of tea to get a meaningful dose
>>
>>75610173
wow so insightful.
prehistoric man lived for hundreds of years. only since modern medicine has lifespan decreased. we are at all time lows with the advancements that have been made. everyone should ignore their health, not look into anything, and just be chill ass vibers instead.
>>
>>75610681
>only since modern medicine has lifespan decreased.
The idea that lifespan was low in ancient times comes from extrapolation from Industrial Revolution data, a period in time that does not reflect past living conditions at all.
>>
>>75610681
Nothing you just said is relevant to anything that I said.
>>
>>75610553
most are protective of cellular reproduction and mitochondrial efficacy which is the main thing that i was concerned with. strongest evidence is currently behind urolithin and sulforaphane
>>75610636
recommend to make the tea cold, as its both easier and contains more catechins. a single 1 tsp of matcha cold will yield around 200 mg egcg, which is a fair amount
>>
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>>75607528
Yup okay, here I go. I'm almost 50, and until I started giving a shit about all of this about 6 months ago, I spent my life being very sedentary, eating whatever and never doing any sport, workout, and barely walking.
Since then, I've been on a mild calorie deficit, high protein whole food diet, work out 3x a week, walk mostly every day, lost 40lbs, reached a healthy BMI level, brought my basic biomarkers within range, and of course, I'm taking a shitload of supplements.
They include:
- the entire BluePrint stack. Yes, I fell for Bryan Johnson's disarming mormonic ways. No enough room to listing everything here, but go glaze your eyes at https://cdn.shopify.com/s/files/1/0772/3129/2701/files/Product_Nutrition_Facts_Master_-_Starter_Kit_Public_-_Mobile_optimised.pdf if you're curious.
- Omega-3 (was 1g, bumped to 4g)
- Vitamin D (5000 IU on top of 2400 IU in BP, so like, a lot.)
- ZMA (zinc, magnesium, B6)
- Melatonin 300mcg
- TMG (2g)
- Acetyl L-Carnitine (1g)
- Lions Mane (2g)
- Gotu kola & Pycnogenol (might be a meme)
Also some powders for good measure:
- Collagen Peptides (20g)
- Creative (5g + 2.5g in BP)
- Taurine (6g + 1.5g in BP

Prescription wise, I used to take a blood pressure pill, but losing weight made that unnecessary.
I take 1mg of finasteride a day, 10 months a year (taking 2 months off/year to donate blood.)
I also use topic minox foam twice a day.

My diet is loaded in "good fats" from nuts, avocado, EVOO and fishies, along with fresh berries, whole fruits. Most meals consist of cruciferous veggies + lean protein.

What's next? More dubious supplements I imagine, as I'll frantically google everything you guys are listing looking for the next best thing.
But also, possibly, hyperbaric oxygen therapy, because we live in the future and stuff.
>>
>>75610855
You're probably going overboard with vitamin D and why would you increase your oxidative vulnerability with omega-3s?
>>
>>75610855
When I saw >>75607568, I realized I forgot to give you guys my skin care routine, which is honestly kinda boring. Just some retinol serum at night with sometimes a retinol night cream on top of it, and some SPF 30 suncreen lotion with ceramides, hyaluronic acid and all the good stuf, for the rare days I go outside.
I have a Whoop band which tells me how to live, so I generally get enough sleep with "high consistency" and "100% performance", whatever that means.

>>75610875
Yeah.. My doc said he wants to get my vitamin D levels tested, so we're going to do that. I have tried to lower it before, and my mood tanks fast. Well not my mood per se but my.. outlook? willpower? ability to give a shit? Whatever that is. So I've been keeping the dose high, and hoping I don't catch vitamin D toxicity.
> increase your oxidative vulnerability with omega-3
I have no idea what that means. I do eat a lot of mixed nuts (roasted, never salted) and I'm trying to guesstimate what would keep a happy omega-3/omega-6 ratio here.
>>
>>75610855
taking way too much supplements
>omega 3 at 4g
your body can't even utilize that much alongside your normal dietary fat intake that's pointless unless you are cutting fat macros out in other places.
>vitamin D
5k units isn't a lot, but you have no K2 posted here, so you're a literal idiot
>ZMA
You only needed to supplement magnesium glycinate because of the vitamin D correlation depleting magnesium.
Zinc could have been gotten from a multivitamin at much cheaper cost.
>melatonin
Jesus christ kid why, you already take collagen peptides which is the only deficiency that has a correlation to sleep disorders. Just eat some fucking fruit dumbass for vitamin C which preserves melatonin.
Not to mention while we are at it, if you're already supplementing collagen and if you added magnesium-glycinate.
Why not low dosage NAC for the glycine+cystine==glutathione gains which further protects melatonin meaning you can stop supplementing melatonin altogether.
Since too much melatonin actually causes insomnia.

The more i learn about supplements, the more I learn they are suppose to microdosages, that less is always more because of their competing absorption, nullifications of eachother, and adverse interactions.
>>
>>75610892
>5k units isn't a lot, but you have no K2 posted here, so you're a literal idiot
You're the idiot because you don't need supplements to get enough K2.
>>
>>75610889
>I have no idea what that means.
Maybe you should learn about PUFAs.
>I'm trying to guesstimate what would keep a happy omega-3/omega-6 ratio here.
That ratio only matters if you depend on conversion to meet your EFA requirements.
>>
>>75609386
"And the such"
Sorry for not being an overly precise cracker.
>>
>>75610892
> taking way too much supplements
Agreed.
> your body can't even utilize that much [omage 3 at 4g]
Yeah I'll readily admit I'm unclear about that. It feels like you and >>75610915 are trying to tell me something, but I don't think I quite grok it.
> you have no K2 posted here, so you're a literal idiot
I thought the link to the Blueprint stuff was big enough, but maybe not. Relevant excerpt:
Vit K2 - MK4 5mg
Vit K2 - MK7 0.6mg
> Zinc could have been gotten from a multivitamin at much cheaper cost.
I am not optimizing for cost. I am old, and therefore loaded.
For Zinc in particular, I get 28mg from the ZMA, plus 15mg from BP.
> melatonin rant, you're supposed to microdosage, etc.
300 mcg is darn close to a microdose for melatonin. I sleep fine without it, I take it for its potential anti-aging benefits (see https://www.healthline.com/health/skin/melatonin-anti-aging)
> Why not low dosage NAC for the glycine+cystine
From the BP stuff again:
N-Acetyl-Cysteine (NAC) 1200mg
Glycine 1.2g
> you can stop supplementing melatonin altogether
Maybe, but natural melatonin production decreases with age, so what may be good advice for youngins may not be appropriate for me.
>>
>>75607528
https://www.rapamycin.news/t/challenge-my-drug-stack-be-ruthless-but-honest/17838

Here is a good discussion regarding anti-aging supplements and medications.
>>
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>>75607791
Finasteride only causes sexual effects in 2-3% of men above placebo and all of them are reversible. Often times, ASCVD starts acting up in your 20s and 30s causing ED due to diminished bloodflow and men who just happened to take finasteride at that time blame it on finasteride. Or they get depression and nocebo themselves.
>>
>>75608524
What matters is muscle NAD+ and supplements have ALL failed ot increase that. Simple exercise does though, even in older individuals. Hence anything more than a basic dose of niacin is pointless.
>>
>>75609543
>>75610098
All of reddit and the hairloss forums already tried that. If it worked in humans, you'd see a bunch of hyperresponders like with minoxidil, finasteride and dutasteride but we don't so this shit is pointless.
>>
>>75610173
No lottery winner ever invested in the stock market, therefore investing is stupid.
>>
>>75611010
>my lack of proof is reason to believe
Go for it
>>
>>75610615
You don't understand, if something is natural it must be good because nature is good.
>>75610855
STATINS
>>
>>75610987
>big stack of blood pressure and cholesterol meds

that's a hamplanet I think
>>
>go on statin
>cannot go off statin

That's pretty much death, you gonna be chained to a pharmacy the rest of your life?
>>
>>75611017
Humans are fucked by default regarding blood pressure and cholesterol so nothing short of miracle genetics or medication can help. Fucking Egyptions had heart disease and they didn't have muh microplastics or muh seed oils.
>>
>>75610855
>nutty pudding
wtf lol
>>
>>75611018
More like:
1. Decide to go on a statin
2. Stay on a statin for X years
3. Decide to quit statin because of retarded reason Y
4. Still have prevented X years worth of plaque buildup and even reversed some
>>
My neighbor is 83 years old. He lives alone. He has no family. He just wakes up and exists and goes to bed and does it again and again and again.

I am 30 and have hated being alive for the entirety of my life.

I deeply struggle with visualizing myself in that man's position. How does he exist? I barely exist.
>>
>>75611031
You don't need to be happy to stay alive.
>>
>>75611025
If I need medications then I don't deserve to live, this is a mindset I've had my entire life and it is not ever going to change. If I could change that point of view, I would.
>>
>>75611035
Then you should kill yourself.
Other people have decided not to let themselves get fucked over by nature and society and chose to take matters into their own hands by taking medication to extend their lives.
>>
>>75611025
1. some people get literally 0 plaque buildup, it depends a lot on both diet and genetics.
2. bromelain clears that shit out pretty well.
>>
>>75611041
Oh I am nearly there, nearly there
>>
>>75611042
>1. some people get literally 0 plaque buildup, it depends a lot on both diet and genetics.
Yes, genetic lottery winners. My family is fucked in that regards so I needed to act asap.
>2. bromelain clears that shit out pretty well.
Plaque is difficult to remove even with high intensity statin therapy. There are acute therapies after a stroke or heart attack that could save you from death.
>>
>>75611053
describe statin vs beta blocker
>>
>>75611060
Statin: lowers number of bad cholesterol particles in your blood flow which results in less plaque buildup or even reversal
Beta blocker: lowers blood pressure which results in less cholesterol particles getting stuck in the cell walls; also decreases mechanistic damage from high blood pressure
>>
>>75611070
Please make an argument for why someone would begin to take medications(taking away their freedom, chaining them to employment and pharmacies for life in order to keep getting their drugs).

I am regularly suicidal and homeless often it's very very hard to convince me to take medications
>>
>>75611082
Medication doesn't take away your freedom any less than having to eat, breathe, shit, pay your taxes or brushing your teeth. While you're on them you enjoy their benefits and if you ever decide to quit them you'll still have benefited.

If you want to die, I can't really convince you to take medications. I know SSRI aren't exactly great for men and wellbutrin is a mixed bag. To give you an example of what convinced me to take medication. I used to be balding and was very depressed about that fact. Then I took finasteride and within just 6 months I regrew sooo much hair and that made me really happy and try a bit harder to stay alive.
>>
>>75611095
SSRI makes me last as long as I want in bed. I don't see how that's a bad thing.
>>
>>75611095
Being wildly mentally ill steady employment has been impossible my entire life, I've never been able to do it.

It is so many things conflicting together that make medications scary for me, I have to first get a job and hold it long enough for health insurance, and then I have to be able to adjust to my new life.

I am in too many pieces.
>>
>>75610173
>no long lived person
>all long lived persons
i'm impressed you were able to gather such complete data. Care to share some details? How many is "all long lived persons" and what is the age cutoff to be included?
>>
>>75611106
I have zero libido on SSRI which is apparently a common side effect, hence why they are better suited for women.
>>75611112
Maybe focus on getting steady employment first before you focus on other things. The longer you stay homeless the more fucked you are in all aspects of life which will eventually lead to your own demise. If you can afford a gun, maybe try pointing it loaded at your head and see if you actually want to live. Don't actually shoot though as I don't want to be liable for that.
>>
>>75611126
>>75611126
oh i cant be anywhere near a gun i will definitely have a moment and do it
>>
>>75611014
> STATINS
Yes, I'm wondering about that. I was able to lower my LDL from >100 to ~85, but cool people keep it below 70.
I think I'm going to give myself a few months to see if lifestyle changes are sufficient to get there, but if not I might consider statins indeed.

>>75611024
> nutty pudding
It's not that bad, basically some cocoa + protein powder with various fun things thrown in and no weird fillers.
I throw a handful of mixed nuts in mine, then I cover it with fresh berries before stirring the whole thing until it looks like clumpy mud.
Delicious clumpy mud. Well. Edible clumpy mud, at least.
I did however just realize it comes with 3g of omega-3 of its own. Hmm. Maybe I don't need to pop *that* much fish oil pills.
>>
>>75611185
>I think I'm going to give myself a few months to see if lifestyle changes are sufficient to get there, but if not I might consider statins indeed.
The thing about statins is that you can eat like shit and not have to worry about your LDL. If you're genetically inclined for diabetes you should just regularly do a test just in case.
>>
>>75611117
Feel free to show me lone lived people who took any of these
>>
>>75611464
Kissinger
>>
>>75611053
how can you check your current levels of plaque buildup? are there any indicators
>>
>>75611053
>>2. bromelain clears that shit out pretty well.
>Plaque is difficult to remove even with high intensity statin therapy. There are acute therapies after a stroke or heart attack that could save you from death.

Bromelain is actually being studied as an alternative to statins: https://ijmscr.org/index.php/ijmscrs/article/view/1698

Nattokinase is another enzyme that can directly dissolve arterial plaque.
>>
>>75607528
chlorine dioxide
>>
>>75608033
>Save your money
This will always be the most retarded narrative because you can get a pretty comprehensive stack for like 1 dollar a day. You can't get a healthy diet for 1 dollar a day, you'd struggle to get a properly min-maxxed diet with even 10 dollars a day.
>>
>>75608033
>You can improve lots of "hallmarks" of aging without affecting aging at all, a hallmark of aging is having gray/white hair - that doesn't mean dyeing your hair black will make you a lot younger. That's essentially how the "anti-aging" industry works.

Uh, from the study linked in the OP post...

>Published in the Journal of Gerontology: Medical Sciences, the study shows that older humans taking GlyNAC for 16-weeks improved many characteristic defects of aging. This includes oxidative stress, glutathione deficiency and multiple aging hallmarks affecting mitochondrial dysfunction, mitophagy, inflammation, insulin resistance, endothelial dysfunction, genomic damage, stem cell fatigue and cellular senescence. These were associated with improvements in muscle strength, gait speed, exercise capacity, waist circumference and blood pressure.

This strikes me like the *polar opposite* of using hair dye to cover up grey hair. This looks like actually fixing *some* of the underlying degradation process.
>>
>>75607528
what do y'all niggas think about ashwaganda
>>
B-50 complex
500 mg Vitamin C
2000 IU Vitamin D or lots of sun
400 IU Natural Vitamin E
100 mcg selenium
2.5 oz Carrot for Vitamin A and fiber


3 times times a week

odorless garlic
100 mcg Chromium
Resveratrol
Kelp for Iodine
3 mg Boron
A to Z multivitamin
400 mg Magnesium
25 mg Zinc
800 mg Quercetin helps allergies

Other


Calcium
Curcumin
EGCG green tea extract
Fish Oil

just as important is to avoid processed food
>>
>eating raw ginger
>lots of polyphenol rich foods like olive oil, berries, veges
>green tea
>low stress
>regular, long, good quality sleep
>a place you feel comfortable in
these have worked for me, at 29 people said i look early 20, some even 18
>>
...and not a single word about copper peptides....
>>
>>75612458
well then, what do you know.
>>
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Thoughts on my stack? Anything I should add?
>>75612458
Topical or oral?
>>
>>75612075
All current tests fucking suck. If you had any ancestors who ever had a stroke or heart attack, consider yourself at risk.
>>75612107
Both of those are based on shitty Chinese research.
>>
>>75612667
ECGC is a fucking meme
You don't need as much B3
Fisetin and spermidin are worthless
Reduce your fish oil intake
Cycle NAC
>>
>>75610855
I should get into the supplement industry and start scamming morons aswell
>>
>>75612289
You're correct.
At the same time, >>75608033 has a point too, the "anti-aging" industry is a nest of grifters selling dreams to desperate people. I should know, I'm their exact target audience.
And so, yes, I do take my GlyNAC, and all kind of other substances that work wonders on fruit flies, lab mice and the occasional human cells in a petri dish. And I also color my hair. Call it an age-affirming procedure, or something.

>>75613404
Unironically yes. Just don't be too obvious, like the TAM-818 scammers, and you'll be fine. Heck, piggyback your products on some promising studies, and I'll probably end up buying your garbage.
>>
a banana
>>
>>75612667
idk, I'm just slightly puzzled by your single gram of collagen peptides, that's basically a microdose.
on the other hand, 42g of milk thistle seems like an improbably large amount. typo, or trying to find the toxicity level of a generally harmless plant?
>>
I'm 30, don't eat clean at all except for cuts, the last time my LDL was measured was in the middle of a bulk and it came out exceptionally low (lower than the lower treshold of the lab norm), same thing happened when I measured it randomly in my early 20s. Is it a good thing?
>>
>>75612667
Do you have any reason to take any of this
>>
>>75613475
Yeah you're fine people have no fucking clue how any of this works lol
>>
>>75613231
ECGC is one of the worst studied and beneficial compounds known
>>
>>75608033

You can literally slow down aging by taking supplements which slow down the process (i.e. oxidation by free radicals) this is supported by plenty of research. Every country which has a diet rich in antioxidants (e.g. Japan, Hong kong, Spain, Italy) has a longer life expectancy than countries who don't and generally their citizens look younger and healthier as they age.
>>
>>75613578
Which supplements?
>>
>>75612667
why only 1g of collagen? take 30g of peptides instead
>>
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>>75607562
>Nattokinase
Not to downplay your effort here but what is the reason behind this?

The physiological state of the immune system is to hold a balance between too many clot formations (thrombosis) and not too much fibrinolysis (preventing or cleaving clots). The problem with liver diseases is that the liver is responsible for synthesizing the factors for both ends of the spectrum.
So supplementing with Nattokinase might shift the balance towards a state that might do more harm to you than good.
But then again, I don't know your tendencies towards blood clots or hemorrhages in form of petechiae for example.

t. 3rd year med fag
>>
>>75613743
I was also a very heavy pot smoker, and have a family history of aortic aneurysm.

It's basically just a cycle to grease the gears again since I'm trying to be healthy now. Not a permanent thing.

That's my logic, a heavy cardiovascular system to rejuvenate every cell I've deeply abused.
>>
>>75613606
Crack
>>
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>>75608033
>dont take anything
>take multivitamin
anon, are you mayhaps retarded?
>>
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>>75607717
>plausible target (induced ALDH activity, inhibits GABA effects)
>went through research and trials
>has above negligible effects
That's unironically some of the first obscure supplements in this thread that I found that isn't bogus. Thanks.
>>
>>75609939
>facial fuel
>People are always surprised
>develop nasolabial
its called suicide fuel, and you look 40 if you have nasolabials, no way around it
>>
>>75613869
some people have nasolabials as early as 20
>>
>>75607528
Most soientists currently agree that if you're 40 or under none of that shit is going to do anything for you. Use your money on the highest quality food, gym memberships, massages, etc. Be lean, take creatine, avoid the sun most of the time, and you'll look like you're 28 when you're 40.

There are good arguments for some supplements if you are 40+ but not really much data to support their usage yet.
>>
>>75607528
It's a scam. NAC makes you an emotional zombie. Is that worth the anti aging effects?
>>
>>75607528
I'm pretty sure hydrolzyed collagen or whatever it's called is the best one.
>>
>>75607562
Just take the McAfee stack and you'll live. >>75607598 redpill me on the sleep stack pls
>>
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>>75614106
>redpill me on the sleep stack pls

All the "sleep-inducing" drugs basically suck to one degree or another. Picrel trazodone for example woke me after an hour tripping balls and I eventually figured out why and discontinued it. Ambien wasn't much better, but I didn't see any walrus. The Lunesta moth can fly away cuz shit just didn't work. All benzos work slightly in the short term, but there is a risk of seizures and dependence with continued use. Seroquel is a titty grower. 3-6mg of melatonin and 25mg of diphenhydramine are decent enough for occasional use. Magnesium, Glycine, L-theanine and valerian all have some marginal efficacy in inducing sleep, but nothing great.

Iodine and methylene blue both consistently reduce my sleep requirements by about 1.5 hours when combined at 1mg and 5mg respectively.
>>
>>75613993
>some people have nasolabials as early as 20
15, niggers are born old
>>
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>>75614329
>[reverse minor chud lines effectively with repeated overnight application, especially if combined with phototherapy and topical retinoids]
>>
>>75614355
>>75614329
once ur facial fat sinks its over
>>
>>75614384
>once ur facial fat sinks its over
Im getting my fat sucked out of my love handles, and Im gonna inject it into my face. How stupid of an idea is that?
>>
>>75614300
FYI chronic use of Diphenhydramine has been linked to increased risk of dementia
>>
>>75614300
Iodine? Like Lugol's?
>>
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>>75614420
probably full retard unless you're really looking full Skeletor mode. picrel.

>>75614526
this is why I say "occasional" and "25mg" lmao

>>75614596
I just eat kelp.
>>
>>75608780
bruh
>>
>>75614729
>probably full retard unless you're really looking full Skeletor mode. picrel.
I dunno, the guy whos gonna do it does botox all the time, but I will be a first patient that will attempt a fat transfer at his place. I got a nice price, I want it to replace filler injections, which are kinda troublesome due to how they work. I dont wanna fuck up my face tho, Im kinda scared
>>
>>75614786
I stay away from fillers/botox/surgery but go heavy on phototherapy/cosmetics/topical chemo. I'd probably go for one of those thread lift procedures first if my cheeks were really sinking badly.
>>
>>75614833
>fillers/botox/surgery
I already got mild fillers and botox, its a nice way to keep your face full, as well as let your skin rest a bit from all this work. Mind you, botox and fillers only works if you have youth to preserve. Its not like you can get a botox at 50 to look 20 again. You can get it at 20s till 50s, to keep the 20s tho
>>
>>75614867
also hella expensive, can have a fair amount of side effects, and doesn't really do much to target the underlying pathologies of aging. a $50 IPL unit or a $4 roll of duct tape or some jello is a way better investment.
>>
>>75614891
>$50 IPL unit or a $4 roll of duct tape or some jello
elaborate
>>
>>75614905
>https://scholar.google.com/scholar?q=intense+pulsed+light+therapy
>https://scholar.google.com/scholar?q=gelatin+supplement+skin

Duct tape has a lot of literature for wart removal, but protip: does a lot of "off-label" shit to skin generally involving increased autolysis and smoothing.
>>
>>75614922
I mean both of those sound really good, but what if Im losing bone mass? My skin is nigh perfect, but Im getting hollow temple and getting slight nasolabials from not enough mass in the face. More collagen wont really help me in this case, I need something else. Also, yeah Im goin for that "life begins at 12%" look
>>
>>75614949
>what if Im losing bone mass?

then you might have boron/calcium/chromium/vitamin D/vitamin K/magnesium/manganese/selenium issues or something even more abstruse. I think Bryan Johnson breaking his ankle recently has proven that 2-3mg of Boron is not enough lmao.
>>
>>75614993
>then you might have boron/calcium/chromium/vitamin D/vitamin K/magnesium/manganese/selenium issues or something even more abstruse. I think Bryan Johnson breaking his ankle recently has proven that 2-3mg of Boron is not enough lmao.
well maybe, but I have a nice diet and take those sups already. Granted I havent been doing it throughout my entire life, but still. I believe its partially genetics, and partially, well, we're just getting older. Im keen on doing it, if I bog myself Ill report it back for all you to laugh at the retard
>>
>>75615012
if all your minerals are normal enough and your bones are still disappearing, see some kinda orthopedic doctor to get tested for osteoporosis or some kinda rarer bone resorption disorder.
>>
>>75615021
>if all your minerals are normal enough and your bones are still disappearing, see some kinda orthopedic doctor to get tested for osteoporosis or some kinda rarer bone resorption disorder.
Im already going to a doc, its not osteoporosis, but my bones dont fucking work too well
>>
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>>75615026
>Im already going to a doc, its not osteoporosis, but my bones dont fucking work too well

sounds like you might need a second opinion and more testing then, because it sounds like you probably hit the reverse lottery and got some kinda rare-ass bone disease(s).
>>
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>>75614355
>>75614729
>>75614867
>>75614833
you cant really stop your facial fat from sinking, can you? I dont see what ducttape is gonna change about it.
ryan looked totally fine but he couldnt stand how he looked so his face is now completely filled to the brim

once it sinks to a certain point you cant really get away with "just being low bf%" anymore. you lose your defined geometric cheeks.
>>
>>75615114
"low bf" is really not good advice, there is actually a specific range between about 9 and 16% (which protip: is the healthiest) where facial fat sinks minimally and your cheeks do not appear too hollow.

I'm not sure if duct tape really reverses fat sinking, but it definitely leads to semi-ish-permanent skin tightening.
>>
>>75615181
but as you can see ryan is perfectly healthy, not too slim not too fat, yet his face has sunken in a little bit before 30
>>
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>>75615252
>perfectly healthy

a dangerous two-word meme pushed by the medical establishment to cover up contradictory research on optimal diet and exercise, and avoid running tests they arbitrarily deem "medically unnecessary."
>>
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>>75613704
>>75613448
The collagen is a side product in my hyaluronic acid complex. Need to buy it seperately, you're right.
Pic related is the milk thistle I take
>>75613487
longevity and liver support
>>75613231
>ecgc
seems good to me
>b3
most products are 500mg min
>fisetin and spermidine
you're probably right about that. Likely won't buy again
>fish oil
will consider halving the dose. Would save me money anyway, thanks
>cycle nac
can you elaborate? Is it not safe to take every day?
>>
>>75615362
he looks fairly healthy yeah
hes also most likely a narcissist as you can tell by his obsession with maintaining a "youthful" look so its suffice to say he takes care of his health
i guess optimal was the wrong word, lets say decent
>>
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>promotes collagen synthesis and hair growth
>>
>>75615445
he's obviously doing *something* wrong to have all those wrinkles though. I'm years older than him and have none of those. maybe it's genetics, maybe it's PubMed skill.

>might be both
>>
>>75615393
>>fisetin and spermidine
>you're probably right about that. Likely won't buy again

just get strawberries and wheat germ instead of the "lol maybe it works idk" meme supplements, lol.
>>
>>75610615
>I don't see why it wouldn't have the same side effects.
Anything that meaningfully blocks 5ar will have fin/dut like side effects.

I got the same sides from astaxanthin. Plenty of people get 5ar inhibitor sides from lions mane and curcumin.
>>
>>75615694
the topical ones that aren't fin/dut don't do that.
>>
sugar
pregnenolone
progesterone
thyroid
aspirin
>>
>>75614993
Based boron knower.
I want to talk about borax, though I don't want it taken off the shelves. Total game changer for hormone regulation, virility & symptoms of RA or similar. LD50 similar to table salt. But apparently poisonous.
>>
>>75615026
Search "the boron conspiracy"
and begin your path to strong healthy bones.
>>
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>>75614993
>>75615021
>>75616069
>>75616078
Yeah, this is super relevant to my interests. See picrel for what came out of my first DEXA scan.
I'm going Monday for another, and then next month at a real medical facility for yet another one (the previous scans are taken in a van, which is cheap, and quick, while the medical facility is making me wait almost two months, but the results will presumably be medically meaningful, or at least taken seriously by my friendly neighborhood PCP.)
What's annoying about this is that I'm taking a whole lot of supplements that should help with this.
Calcium 250mg
Magnesium 450mg
Vit D 7700 IU
Vit K2 5.6mg
Boron Glycinate 3mg
Manganese Citrate 1mg
Selenium 30mcg
Meanwhile here I am getting worried my limbs might snap in half if I try lifting too much. Fantastic.
>>
>>75611126
>I have zero libido on SSRI which is apparently a common side effect, hence why they are better suited for women.
Why would you want your wife/gf to have zero libido?
>>
>>75616078
https://ehp.niehs.nih.gov/doi/pdf/10.1289/ehp.94102s783
>>
>>75616307
bone recomposition is extremely slow sometimes it can't even happen the best hope is just to hold what they have
>>
>>75614069
>Most soientists currently agree
midwit take



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