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File: hrtgen.png (1.07 MB, 2000x2721)
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previous: >>42047951

• Help, advice, guidance on meds and dosages
• HRT related medical experiences and research
• Availability and pricing of medications
• Rational and scientific discussion

See following post for a pharmacy list.

Survey: https://1drv.ms/xs/s!AudRJceTA5C9c2G5lCV2Avq0kQ0
▶ Survey data: https://1drv.ms/x/s!AudRJceTA5C9cyIWo6_X14AvHyM
▶ HRTGen Data Analysis: https://1drv.ms/f/s!AudRJceTA5C9gRLLWnbpdzlIxe4r
▶ HRT Info Sheets: https://1drv.ms/f/s!AudRJceTA5C9gQnyM7wxZcBGWRzW
▶ Pill ID: https://www.drugs.com/imprints.php
▶ DrugBank: https://www.drugbank.com/
▶ Basic HRT: https://apps.carleton.edu/campus/gsc/assets/hormones_MTF.pdf
▶ HRT ranges: https://www.hemingways.org/GIDinfo/hrt_ref.htm
▶ Powers Method: https://powersfamilymedicine.com/s/Healthcare-of-the-Transgender-Patient-V60.pptx
▶ Endocrine Society Guidelines: https://academic.oup.com/jcem/article/102/11/3869/4157558
▶ Transline Guidelines (with bicalutamide): https://transline.zendesk.com/hc/en-us/article_attachments/360047702053/TransLine_HRT_Guidelines_FINAL.pdf
▶ WPATH SOC: https://www.wpath.org/publications/soc
▶ TransDIY: https://www.reddit.com/r/transDIY
▶ Blood tests (US): https://www.privatemdlabs.com/, https://www.labsmd.com/
▶ Blood tests (UK, Ireland): https://www.medichecks.com/
▶ Blood tests (Canada Only): https://bloodtestscanada.com/
▶ Blood tests (Sweden): https://werlabs.se/
▶ Blood tests by mail: https://www.letsgetchecked.com/ DIY capillary blood samples. Expensive.
▶ Lab test guide: https://www.healthcare.uiowa.edu/
>>
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▶https://www.inhousepharmacy.vu/t-shipping.aspx- Has been popular in the US. Ships from Vanuatu to some countries.
▶ euaibolitatgmaildotcom - Ships from EU to Worldwide.
▶https://unitedpharmacies-uk.md/(UK only) - Ships from HK.
▶https://unitedpharmacies.md/(US only) - Ships from HK.
▶https://alldaychemist.com/- Ships from India to some countries.
▶https://shape-shifter.webnode.page/- Ships from Turkey to Worldwide.
▶https://stayhealthynow.co/- Ships from Turkey to Worldwide
▶https://amazing4health.com/- Ships from Thailand to Worldwide.
▶https://favskinhouse.com/- Ships from Thailand to Worldwide.
▶https://goodstuffstore.net/- Ships from Thailand to Worldwide.
▶https://otc-online-store.com/- Ships from Russia to Worldwide.
▶https://www.weborderpharmacy.md/(US only) - Ships from India.
▶https://www.weborderpharmacy-uk.md/(UK only) - Ships from India.
>>
File: hrtgen3.png (386 KB, 1500x1521)
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Reject modernity
>>
>>42214711
I know this is a stupid question but how good is planned parenthood hrt? I can’t really do diy since my mom is nosy and opens up every package of mine also how bad of age is 19 for transitioning
>>
>>42215009
planned parenthood will hondose you but not THAT bad so its ok to start. they don't give some stuff (like bicalutamide or dht gel (i assume ur a tranny so that doesn't matter)).

19 is fine. its not that much worse than 18 and people who start at 18 are fine. just voice train. start now.
>>
>>42215315
If go the route of injections would that lessen the hondose or nah
>>
>>42215486
short answer yes but do your research. a lot of places in the US only prescribe valerate or cypionate in stupid low concentrations so you're injecting yourself with just so much liquid that it kind of sucks so both not ideal
>>
>>42215539
Thank you and where would i do research?
>>
>>42215613
theres usually someone here u can ask if ur dosage is ok. u can also just consult the graphic. r/transsex and r/transdiy have some stuff too. r/drwillpowers has some interesting reads too for really transmaxxing.
>>
>>42215647
Alright thank you again
>>
>>42215009
planned parenthood is not the best but also not the worst. you definitely want to get on injections to avoid any of their hondosing. with injections, you can decide your dose and not be fucked by how often you can refill your prescription. make sure to request the 40mg/ml concentration, which should last your for several months and is most convenient to inject. it will most likely be valerate, but it gets the job done. they also prescribe prog, but i think you need to be on hrt for some amount of time before they will prescribe? not sure how long or if there is some time gate.

the annoying thing though is their blood tests. they will want to test your peaks instead of troughs, but you can lie to them and try scheduling at your troughs (just don't mention that, let them think it's your peak). also they follow wpath levels
>>
>>42215009
>>42216560
i forgot to mention. some pharmacies seem to have trouble with stocking ev 40mg/ml. i have had most luck with walgreens pharmacies. call a nearby one and ask if they have it in stock or if they are able to stock it (and how long that may take)
>>
is there like a list of expected changes and corresponding timelines?
>>
I am responding exceedingly well to a hondose 4mg EV and 200mg spiro daily since just July 2025.
>>
I was born to fem out. I want to be the cutest fem version of myself possible. I suck cocks exclusively so I'm not gay. Women are gay. Wanting to be around women is the gayest thing possible.
>>
>>42214711
is 1.5 years too early for prog?
>>
>>42217381
Go for it, 1y+ is enough
>>
PSA

You dont need a bank account to buy bitcoin for hrt. You can use a non KYC exchange which allows for non bank payment options and a self custodial wallet
>>
>>42215009

I have a PP prescription after I already started DIY, they put me on the highest oral dose (8mg) and asked me about injections last time, I'm too much of a puss to inject myself though

They also gave me progesterone but I'm paranoid about the DHT backdoor so I'm waiting on the bica I ordered
>>
Does anyone think if HRT would do anything at the age of 24-25?

I am 20 and I live with my family. 1st year in electronics eng. and I am estimating I may get economical independence in about 4-5 years and I am planning on starting HRT a year before I leave this house.

I got two besties (one lesbian and one gay). They also wanna gtfo of family home and we might share rent in the future. So "economic independence" means bare minimum, not living in the street.

180cm 63kg 19.4 BMI if that helps. I never gained more weight than 20 BMI. I am a fucking brickhon tho.
>>
should i be on fin or dut if I had hairloss pre-hrt? HRT has restored most of it, but i stg it feels like its going again in the very margins but idk. also as a brokie, what's the cheapest possible source of either?
>>
>>42219135
End well this will NOT. Absolutely do not start your HRT journey while being dependant on two loose cannons for your living. You can start now, shit takes time to work anyway.
>>
>>42219135
start now! seriously, you would be letting T fuck your body for 4-5 more years. i started at 24 because i got more masculine. i still had a babyface at 20. now im stuck with a much more masculine face. start now!!!
>>
>>42219775
Well the problem is I can't suddenly get more feminine in my family's home. Men don't suddenly grow booba and get softer skin out of nowhere. I know shit takes a long time but I don't believe you could hide the effects of HRT for 5 years could you?

The "loose cannons" are one of the most awesome people I ever met. It is hard being lgbt in turkey (or in any middle eastern country, for that matter). We look after each other, but I may earn enough money myself to not be homeless if that doesn't go as planned.

>>42220114
This really puzzles me, but the problem mentioned above persists. I can't hide the fact i am on HRT unless there is some miracle compound which can do exactly that. I know breast growth could be inhibited but i do want breasts and I heard those meds have a lot of unpleasant side effects. Plus the other effects of HRT are hard to hide too.

I do still have a babyface-ish and it is getting worse every day. My dad grew beard/aged pretty late so I stayed a twink for a longer time than other people, but that extra time is about to run out too.

I did think about going on HRT and stopping once it starts to become too noticeable. Somebody on plebbit told me this approach was not that bad, it would just mean T would undo some of the work done by E and everything would move much slower. Is it really harmless?
>>
>>42216615
its only been a couple weeks and i think im noticing things is this placebo
>>
>>42220511
I'm in the same situation, been on it for three weeks and I'm pretty sure I've noticed a few changes, mainly to stuff like my orgasms, my mood, skin, sweating, etcetera, though I don't know if it's all in my head because I haven't gotten a bloodtest done yet; but that's mainly due to the fact I'm broke rn, I could use some help knowing which test to get on medicheck though... I'm in the uk and currently taking 12.5mg of cypro and 4mg of estradiol valerate daily
>>
I've sucked dick twice in the last week and I'm gonna suck dick four more times this month. It wouldn't have been possible without HRT.
>>
>>42220511
>its only been a couple weeks and i think im noticing things is this placebo
It takes as long as it does for cis girls even at the proper dosages--wait at least six months to see anything.
>>
>>42224922
ok so theres not like a chart of expected changes and a range for the earliest/average/latest they can occur and same for finish? i know some things can take a decade im just want to know how much is in my head and what is realistic
>>
>>42225586
https://transfemscience.org/articles/transfem-intro/#effects-and-timeline
read everything
>>
>>42225639
thanks thats exactly what im looking for
>>
>>42223114
>I've sucked dick twice in the last week and I'm gonna suck dick four more times this month. It wouldn't have been possible without HRT.
I am trying to get HRT now but I doubt any cis boy would let me suck it until I pass. I think I might like boys? Maybe? I don't know about that and am mostly worried about not letting testosterone rape me anymore. :'( Women are sexy and all but men are like, hot? I don't know. Maybe I am pan or something.

It is sad to be raped since even after I do get HRT, I can't really get unraped. Just more recovered from being raped. *crying trans girl noises*
>>42225684
>>>42225639
>thanks thats exactly what im looking for
Different anon: that chart is just what is expected for onset--the changes may start later for you because of genetic variation so don't be too hard on yourself or worry too much. You might be able to determine a more accurate timeline to your case if you have cisters and know when they started puberty/had certain things happen. Good luck! <3
>>
>>42225764
>the changes may start later for you
i thought i heard people talking about changes in the chest area in <weeks> and uh yeah i think its happening
>>
>>42219596
fin and dut are for just blocking t conversion to dht. if you have t that u want to keep then yeah sure.

reliable rx has some i think
>>
>>42218899
8 oral sucksssss. 8 sublingual is OK.

boofing it per hour best guesses right now for most people will give less DHT conversion. u can also get synthetic metabolytes of prog to bypass it completely but u do have to inject those

>>42219135
holy shit anon start right now.
>>
>>42219135
It’s just genetics at that point, don’t bother waiting just start ASAP going to take ages to see noticeable changes and everything can be hidden anyway.
>>
>>42219135
>>42226347
>holy shit anon start right now.
Anonette listen to this or you will hate yourself--trust me, I went through this and cannot emphasize this enough START NOW!!! JUST DO IT--TRUST US!

>>42225764
>Good luck! <3
Trans fems are too nice. :3
>>
>>42220472
>I heard those meds have a lot of unpleasant side effects
They **can**--they might not for you, and even if they do, they aren't as bad as waiting. Also, mono-therapy can avoid those effects and is just as easy to do--it is also much cheaper if you need to go DIY for any reason.
>>
>>42214711
What things should I be testing for to help troubleshoot my HRT? I've been on E pills for 1 year, injections for 5, progesterone for 2, and am one year post-orchi. Levels of estrogen have been historically high (more than 500pg/ml), and levels of testosterone very low (usually about 20ng/dl).

I just need to know what I should be testing for before I actually pay out of pocket for my tests lol
>>
>Post-orchi
>stop taking estrogen
>literally never bloated again, it’s been a month and i still have not experienced bloating
Could I just do progesterone mono therapy DIY? I seriously can’t believe this. I’ve been dealing with random bloating my whole transition and since I stopped estrogen it just doesn’t happen. My figure is perfect 24/7 now.
The only downside is I will not age slower now.
>>
>>42227249
I don't know the amounts but high levels of e past a certain point doesn't do anything and is just wasted.

>I've been on E pills for 1 year, injections for 5,
I presume you are currently on injections?

>Could I just do progesterone mono therapy DIY? I seriously can’t believe this.
Stopping E entirely will make your body not have a main hormone and can cause health issues and stuff (which is why young trans fems can't just take anti androgens until they old enough to do HRT and instead need to take puberty blockers instead which can cost an insane amount depending on the type...) So no, that is a pretty bad idea, but you could try lowering the dosage of E (if on injections) or spread out its taking to not feel so many side effect of above cis levels for E. This is part of my pregnant women feel like shit throughout the experience.

>The only downside is I will not age slower now.
:'(
>>
>>42227539
How do I figure out how to dose myself properly? When I take recommended dosages I usually end up in the 1000s just because.
>>
>>42227582

For injections, are you using Estradiol Cypionate (EC) or Estradiol Valerate (EV)?
See for typical dosing: https://diyhrt.info/transfem/dosing/#injection-monotherapy-dosingaccurate-injection-dosing
>Adjust accordingly if you have access to blood testing (see Blood Testing section below). Ideally you should be aiming for the lowest possible estradiol levels (that are still above 100pg/mL at trough) that still adequately suppress testosterone < 50ng/dL at trough. Though people usually require trough estradiol levels of 200-250pg/mL to adequately suppress testosterone.

With post orchi testosterone isn't a concern so you don't need to worry about hitting that 200-250pm/mL (note the unit since there are two common units (pg/mL and pmol/L) to measure this and they differ massively in values). However, you still need to get at least 100pg/mL E at the lowest point.

Use this to calculate what dosage you will likely need:
https://transfemscience.org/misc/injectable-e2-simulator/

Fill out the info, select recurring, select something like 90 days to get a good view and adjust the value as needed.

For EC, see https://sim.transfemscience.org/?e=ec_o&d=2&r=y&di=7&xm=90
The graph shows that 2mg should be fine.

For EV, https://sim.transfemscience.org/?e=ev&d=2&r=y&di=5&xm=90
2mg should also be fine.

If you use a different injection type just tell me, and I will calculate it for you if you want help.

For that 2,g, use https://diyhrt.info/transfem/dosing/#dosing-examples to determine how much liquid you need to inject.

[cont.]
>>
>>42227582
>>42227683

[cont.]

Either way, if your blood test's E levels come back under 100pg/mL then up your dosage a bit (try it in the calculator to get a good estimate) and if much higher then lower it a bit. Wait at least a month between blood tests and measure at your trough (just before when you would inject next). Don't worry about having even 150pg/mL--even 250pg/mL is fine and shouldn't cause issues. However, 1000pg/mL is pregnancy levels and will cause typical pregnant problems.

Good luck! :3
>>
>>42227683
Thanks. Can I still get blood work without insurance in New Jersey?
With Estradiol cypionate, how often do I stick myself? EC is what I have rn.
>>
Yaaay
>>
>>42227910

Sorry for the last reply; I "slept" for three hours/took a nap...trans fems really need to get an extra four hours everyday just for sleeping to make up for all our complications...

>With Estradiol cypionate, how often do I stick myself?
https://diyhrt.info/transfem/dosing/#injection-monotherapy-dosingaccurate-injection-dosing
Every seven is what is typically recommended. Have you just been doing it with random-ish amounts at random times?

>Can I still get blood work without insurance in New Jersey?
Unfortunately, I have no personal experience with NJ but if you are just asking if it is doable if you pay yourself then yes, it is. Did you have insurance before? I don't have personal experience with paying for one's own blood tests so I can only point you to resources and let you evaluate your local options.
>https://diyhrt.info/transfem/dosing/#blood-testing
>$50-$150 per test, depending on source
>https://diyhrt.info/resources/bloodtests/
>https://old.reddit.com/r/TransDIY/wiki/index#wiki_blood_tests
>https://transharmreduction.org/blood-tests
>https://old.reddit.com/r/TransDIY/wiki/index#wiki_blood_tests

Those of those seem to push regular blood tests as some insane thing but that isn't quite the case; if your hormone regimen hasn't changed and you waited long enough to measure it since the last change in it, then there isn't much of a need at all. You can find your trough with the calculator again [1] so you can know how long after making a change you should wait but 1-3 months later is commonplace and anything sooner is seen as pointless/bad. The key thing is your trough levels so do it right before when you next dose would be.

1. https://transfemscience.org/misc/injectable-e2-simulator/
>>
>>42228641
>Yaaay
You can't just express happiness without telling us what you are happy about--we live off mutual happiness because our lives suck too much on their own.
>>
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>>42214711
i've been doing fine for the past few years, but recently i've been noticing myself getting hard more often and that my semen was no longer clear. blood tests say my testosterone is at 60ng/dl, so i'm not quite sure what's going on. i've started taking bica just in case, but is this something that i should be worried about?
>>
>>42215009
im currently using planned parenthood. its nice to be able to get immediate access to HRT and supplies, but their care is kind of ass.

you basically have to go in with the mindset you're going to be doing DIY cause they will try to start you on everything else except for injecitons, only to waste your time and money.

im mostly doing DIY based on what i find works for my body but obtaining estrogen and supplies through official means.

currently doing 8mg a week, splt into 4mg every 4 days. finasteride 2.5mg.
>>
>>42229139
dose might be too low or too high, or not frequent enough.
>>
>>42229027
My body has more curves and soft squishy bits now. I was wiggling to myself in the mirror just to see all the new squishy bits wobble up and down.
>>
>>42230752
I hope I get my DIY HRT in the mail soon--I can't wait to get softer!
>>
>>42228980
>Every seven is what is typically recommended
*Every seven days

>Those of those seem
*Some of those

I need to proofread more...
>>
@Grok is this true?
https://mungeribabu.substack.com/p/estrogen-is-really-bad-for-men
>>
>>42214711
Hey, it's been 5 months 4 weeks on E and my sweaty masculine smell came back along with very mild libido related issues. I ordered bica and it'll take a week or so to get here, but i'm just really confused as to how T creeping back is possible considering i inject myself with E at a higher dose.
I don't have any blood work yet...
>>
>>42233670
Very true. And make sure you never ever read anything about population health, that would be very embarrassing for you.
>>
>>42234363
I'm dumb can you explain what you're saying without any sarcasm or obfuscation
>>
>>42234430
>I'm dumb can you explain what you're saying without any sarcasm or obfuscation
Ditto; I am confused too.
>>
>>42234310
blood work would tell u if its T or not. what is your dose oomf
>>
>>42234640
.12 - .13

Sorry about late reply, oomf
>>
>>42235499
0.12 ml of what

mg density and type of estradiol and frequency oomfie
>>
Does the administration method even matter if I have good levels?

>200pg/mL
>>
>>42235508
.12 e valorate mono, 5 day freq (although these past 2 times i've injected early), 40mg/mL, oomf
>>
>>42235584
>Does the administration method even matter if I have good levels?
Certain methods are safer and what not (such as oral/pills being harder on liver/kidneys or something) but not in any way worth worrying about.
>>
>>42235606
5mg shouldnt be low but it could be you need labs

>>42235584
yes. oral 200pg/ml is not the same as injection is not the same as sublingual
>>
>>42235645
>yes. oral 200pg/ml is not the same as injection is not the same as sublingual
Oh...I thought they were asking about blood levels in my reply >>42235626
>>
>been on injections for years
>always injected with the same needle I used to draw, never had any issues
>new clinic gave me these gigantic 18GA needles for drawing and 25GA needles for injecting
>never bothered to use the 18GA needles, just draw and inject with the 25GA
>decide to actually use the 18GA to draw and 25GA to inject like the clinic recommended on a whim today
>Draw with the 18GA
>wtf, the syringe filled up to the proper dose instantly, normally it would take several minutes of messing with it
>change to the 25GA, didn't lose as much medication as I thought
>get ready to inject, spot marked and swabbed, bandaid ready, hold the needle up to the spot
>wtf, needle is already halfway in without me ever noticing??
>finish the injection with no issues

I might be a moron. Turns out using a larger gauge needle for drawing is actually super helpful, and using a fresh needle for injecting makes a huge difference
>>
>>42235645
>yes. oral 200pg/ml is not the same as injection is not the same as sublingual

I'm taking sublingual 6mg daily how would that be different from injections if I have the same levels?
>>
>>42234430
>>42234444
this article claims that estrogen, when taken by men, causes a bunch of things that are either known to be more common in women as a population (auto-immune disorders, breast cancers, VTE, alzheimers) or are more common in the lgbt population due to minority stress (depression, mental health disorders). This article is blatant scaremongering over the effects of estrogen in men when it is a perfectly expected result that transwomen on estrogen would have an increased chance of health issues that majorly affect women as a population and a decreased chance of getting those that effect men, and also higher rates of depression, substance abuse, and stuff like that which are common across lots of minority/disadvantaged populations and not at all related to taking estrogen per se.
>>
>>42236166
So women are more likely to get alzheimers than men?
>>
>>42236394
>So women are more likely to get alzheimers than men?
yes? at least all research suggests that they do, although it's not known why. You can very easily search something like that.
>>
>>42235694
not injecting with a fresh needle is crazy anon
>>
>>42238700
lotsa people use the same really high gauge one for drawing and injecting but i heard its harder with pharma cause the oil is v thick
>>
>>42238700
i kind of have an used needle fetish
>>
>>42239213

also you are dulling the needle each time you push it through something
>>
>>42239226
oh well i cant feel it anyway at 29G



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