Gruffudd met Alice Evans in 1999 during the production of 102 Dalmatians. They moved to Los Angeles together in 2003.[21] On 14 September 2007, they married in Mexico.[22] His best man was fellow Welsh actor Matthew Rhys, a long-time friend. Both are patrons of Trust PA, a UK spinal injuries charity.[23] Evans and Gruffudd have two daughters, born in 2009 and 2013.[24]In an interview in 2020, Gruffudd said that working away from home meant that he and his wife had struggled to spend time with each other in the previous four years.[25] Evans announced the couple's separation in January 2021.[26] On 1 March 2021, Gruffudd filed for divorce.[27] On 14 February 2022, Gruffudd filed for a domestic violence restraining order against Evans. This included protection of his girlfriend Bianca Wallace.[28] On 2 August 2022, Gruffudd was granted a three-year permanent domestic violence restraining order against Evans.[29] On 3 July 2023, an LA judge declared Gruffudd and Evans legally divorced.[30] In 2024, Evans, who has full custody of their two children, took Gruffudd to court to demand child and spousal support which she won.[31] In July 2025, Evans took Gruffudd to court for more child payment support.[31]I was never going to watch 102 Dalmatians again, but if i did i'd never be able to watch it the same way now.