>>109807936
>xcancel is back?
No. Look for alternatives here
https://igwiki.lyci.de/wiki/Privacy_friendly_frontends
specifically
https://codeberg.org/mv12star/shitter/wiki/Instances

>>109856759
>>109859221
bot

>>109858684
>>109859221
I got an updated one: https://pastebin.com/NrthvPas
Please add it to the next OP list

>>109860331
Thanks! Will do

>>109860331
OK, BUT WHAT DOES IT DO!

>>109858728
I was also surprised, it didn't do that until this query. I thought we were over this emoji garbage. Apparently not.

>>109858712
>>109858812
The original alphafold was not an LLM. The newer versions (with AF2 and later) do use LLMs. However, AF family (including AF3) are total trash and unusable in real life. Why do you think there are a bazillion other 3d structure models around, and why do you think there still aren't any ai-generated drugs anywhere? No the schrodinger thing is not ai-generated, even schrodinger had to call out the bullshit PR. It's just ordinary design tools from the 90's with no ai involved.
You will never guess what their greatest 2 flaws are. That's right, they can't generalize and have 0% accuracy on things like antibodies. If you ask it to model a gpcr, which changes conformation if it's bound or not bound to its ligand, you will find that it will "randomly" choose whether to model the bound or unbound conformation, despite no ligand in the input you provide it.
What is the second problem, you ask? Well, it performs worse than homology modeling and other pre-AF approaches when you remove MSAs.

And no, it's not a folding model, it's a 3d structure model. We don't really know how proteins fold and there are a few, rare, basically unfunded attempts to build folding models though.

>>109858712
The nobel prize was 100% political, by the way. Nobody has found a way to make af usable for actual science. It's just a cute tool you use to show stakeholders your molecule instead of just showing them the sequence, knowing the prediction is completely off and not even in the right ballpark.
Go try to predict Claudin-18 right now for example. Hilarious.

No human ever has or will do "protein structure prediction", but homology modeling by humans at the freshman level is still lightyears ahead of anything AF ever produces today.
The real point of competition is AF vs biologically determined structures, such as by crystallography or cryoEM (not NMR, everyone knows that's a scam).

>>109858814
No, and that's not how MoE works at all anyway, in the LLM sense.

>>109860771
Yes they are and if you read any papers on the topic they will basically explicitly state so because that is the definition of how LLMs work, cretin. Nobody's onus but yours to prove that 1+1 is not = 2, inbred.

>>109860916
>things that everyone can see plain as day
that amd tranny and the original pedo who posted the pedoblacked webm are two peas in a pod? yeah we can see that gpu preference has nothing to do with degeneracy

Ryzen 5 9600 for £120 or
Ryzen 7 7700 for £140

what does /pcbg/ think

>>109860857
>Brand fags are so anno -ACK >>109844877
i guess they weren't so annoying in the other thread (i wonder why)

hmmm. I can't help but notice the lack of a 9950X3D2 and Blackwell 6000 in the OP.

NVIDIA BAD.
AMD GOOD.

>>109860019
based

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>>109859875
bring her back instead

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>os-tan era
>wataten era
>satania era
>momoka era
>new game era
>shamiko era
>yuru camp era
>sophie era
>dagashi kashi era
>uni era
>blue archive era

where Sophie?

>>109861198
>>109861202
In the middle of a raging housefire.
Run in and see her. Stay there at least 20 minutes.

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>>109859465
>CRTs are locked to 60Hz

>>109859465
And what resolution will your CRT display at this mythical 200Hz?

>>109860605
1600x1200i

>>109859465
>IPS display for high refresh rate gaming
That's a cherrypick if I've ever seen one.

If you don't mind 4:3 and very low resolutions, but still wank Quake at 300FPS, then CRT is for you

>>109860230
Yeah, it's redundant bingbing wahoo. I mean, I like docker and podman a lot, but I don't see the point in running a whole containerized Linux environment for one souped up new tab page.

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Fonts looked fine on Fedora KDE but I'm having a lot of issues on Debian KDE. Calibri here for instance just loses anti-aliasing at certain sizes.

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>>109860613
I fixed the aliasing by putting this in ~/.config/fontconfig/conf.d/25-no-bitmap.conf:

<?xml version="1.0"?>
<!DOCTYPE fontconfig SYSTEM "urn:fontconfig:fonts.dtd">
<fontconfig>
  <match target="font">
    <test name="scalable" compare="eq">
      <bool>true</bool>
    </test>
    <edit name="embeddedbitmap" mode="assign">
      <bool>false</bool>
    </edit>
  </match>
</fontconfig>

Comment too long. Click here to view the full text.

wincuck here (I promise this pertains to linux)
a program I'd really like to find an alternative to is the windows alarm application that I use for timers, specifically the part where it ducks the volume in other programs to make sure I don't miss it ringing
Even if I had to use a script that fires in terminal I don't mind something like that, but has anyone heard of something like this already so I don't reinvent the wheel?

>>109861125
KClock and KAlarm are probably what you're looking for. KClock even has the ability to wake your computer up from sleep which is insane to me

>>109861125
I use xfce4-timer-plugin on my panel and set a command to play a sound upon timer finish. Obviously only Xfce desktop only.

>>109861219
if your agent is designing the tests of its own accord they're pretty worthless anyway. chatgpt models in particular, had it using a test harness with src.lastIndexOf('})();') more or less injecting data it needed to pass the test.

>>109860680
i think only glm is allowed. qwen is censored.

>>109861219
AI can generate good patterns and bad patterns, and will follow existing patterns, so any issues compound. The question is, can you identify the patterns, can you tell when the focus is on all the wrong spots, do you know if the tests are really testing anything, or simply put, are the vibes good enough to continue?

>>109860090
I let it control my cursor. I trust adstra-chan with my life

New thread:

>>109861344
>>109861344
>>109861344

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yes. it's pretty great. a friendly reminder that fontconfig exists and you SHOULD read the documentation. https://fontconfig.pages.freedesktop.org/fontconfig/fontconfig-user.html

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>TrueType patents expired in 2010
>ClearType patents expired in 2019
didn't used to be the case.

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>>109861087
Eric Lengyel put the patent for the slug algorithm in the public domain a few months ago too.

>>109856785
yeah we know anything other than big cocks are of no interest to you faggot

>>109854600
>lets make preprocessor arguments look identical to runtime branches except more ugly.
WOW what a FANTASTIC idea! (sarcasm)

Starting to become like zig. Not a good look, Drew.

Odin is a better C replacement

>>109854600
Buy an ad, Drew.

>>109857261
>Meanwhile rtorrent reigns supreme.
nobody uses it

>>109854932
This

>>109857261
rtorrent has abysmal performance.

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I use transmission

>>109861051
>TRANSmission
Sorry I'm not gay or faggot, I'll not use that shit.

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>unused memory isn't fucking wasted memory
yeah it is. just like unused time is wasted time.

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>>109857987
Unused memory = wasted memory applies ONLY when we talk about filling it up with cache.
In any other context it's just lazy "developers" spreading fake and gay "opinions".

>>109857987
>Why does Windows think it understand me memory usage needs better than I do?
Because it almost certainly does, unless you're an expert at systems programming and you're doing something very niche (in which case you'd probably be using Linux instead).
That "cached" memory will become available very quickly if it's required for an application.

>>109857987
My gen 5 drive and ddr5…sitting idle

Just kidding I’m generating porn videos overnight

"Unused memory is wasted memory" is developers arrogantly assuming you will be using their app alone on your computer and nothing else

>>109859919
bumping real thread

>Daily Programming Thread
>Game and Engine Development General
>Operating System Development General
>Lisp General
If anything, I think a Compilers & Interpreters Development General would be a good addition

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>>109860714
Be the change you want to see

>>109859919
use case? No seriously.
Even memes like scala has a usecase being used in big data but that is already being captured by python.

>>109859707
>CI
you mean IQ negro?

>>109854158
>Systemd is right.
Only thing I agree with you on. How can you possibly talk shit on DRY principles?

>>109854183
fpbp

I agree with the first two but not the third. Instead of separate programs sending text streams to each other, your OS should be a Lisp environment, and programs just Lisp functions.

>>109854158
UNIX philosophy was never good - it was just all we could do on machines with 8 kilowords of core memory and reel-to-reel tapes.
Since we have infinitely surpassed that, "UNIX philosophy" is literally a red flag (the original Locomotives Act 1865 meaning).

>>109858674
If you need an accessibility tool in order to operate your computer, that makes you either disabled or retarded. So which are you, anon?

>>109860827
What if he's both? Think outside the box for once.

>>109860845
I'm thinking that's pretty likely actually

>>109860862
>not using your feet to control mice
>not turning your old clunky dance dance revolution mat into a giant trackpad
NGMI

>>109860869
I actually got a pair of chink pedals for emacs but it's way too slow. I only use it to operate my wm now.